Results 61 to 70 of about 543,794 (329)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, Volume 20, Issue 6, Page 1556-1590, June 2026.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Lagrange multiplier based transport theory for quantum wires

open access: yes, 2004
We discuss how a Lagrange multiplier method of non-equilibrium steady state statistical mechanics can be applied to describe the electronic transport in a quantum wire. We describe a theoretical scheme using tight-binding model.
Kosov, D. S.
core   +1 more source

VLSI Architecture of Efficient Hybrid Multiplier Using Hybrid Adder [PDF]

open access: hybrid, 2023
Bala Sindhuri Kandula   +3 more
openalex   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, Volume 20, Issue 6, Page 1643-1660, June 2026.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

An extension of Helson-Edwards theorem to Banach Modules

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 1991
An extension of the Helson-Edwards theorem for the group algebras to Banach modules over commutative Banach algebras is given. This extension can be viewed as a generalization of Liu-Rooij-Wang's result for Banach modules over the group algebras.
Sin-Ei Takahasi
doaj   +1 more source

FPGA-Based Multi-Level Approximate Multipliers for High-Performance Error-Resilient Applications

open access: yesIEEE Access, 2020
This paper presents approximate multipliers which are efficiently deployed on Field Programmable Gate Arrays (FPGAs) by using newly proposed approximate logic compressors at different levels of accuracy.
Nguyen Van Toan, Jeong-Gun Lee
doaj   +1 more source

Experimental Demonstrations of Native Implementation of Boolean Logic Hamiltonian in a Superconducting Quantum Annealer

open access: yesIEEE Transactions on Quantum Engineering, 2021
Experimental demonstrations of quantum annealing with “native” implementation of Boolean logic Hamiltonians are reported. As a superconducting integrated circuit, a problem Hamiltonian whose set of ground states is consistent with a given ...
Daisuke Saida   +6 more
doaj   +1 more source

A Spectral Multiplier Theorem associated with a Schr\"odinger Operator [PDF]

open access: yes, 2015
We establish a spectral multiplier theorem associated with a Schr\"odinger operator H=-\Delta+V(x) in \mathbb{R}^3. We present a new approach employing the Born series expansion for the resolvent.
Hong, Younghun
core  

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

open access: yesFEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim   +11 more
wiley   +1 more source

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