Results 71 to 80 of about 543,794 (329)

Multiplying with DNA [PDF]

open access: yesNatural Computing, 2006
A functional machine is not only an assembly of parts, but also an assembly of processes. The processing of each part must obey laws that respect to the property of this part. For example, building any kind of computer entails selecting appropriate components and assembling their properties to function in computation.
Gang Wu, Nadrian C. Seeman
openaire   +2 more sources

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

open access: yesFEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho   +4 more
wiley   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

Characterization of Clinical Phenotype to Glial Fibrillary Acidic Protein Concentrations in Alexander Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine the concentration of glial fibrillary acidic protein (GFAP) in cerebrospinal fluid (CSF) and plasma in Alexander disease (AxD) and whether GFAP levels are predictive of disease phenotypes. Methods CSF and plasma were collected (longitudinally when available) from AxD participants and non‐AxD controls.
Amy T. Waldman   +9 more
wiley   +1 more source

Specifics of Project Management on Industrial Innovation

open access: yesProceedings of the International Conference on Applied Innovations in IT, 2018
The paper offers a scientific and methodological approach to assessing the efficiency of innovative projects which develops and supplements the theoretical bases of innovative projects analysis through the accounting of recursive dependence of ...
Stepan Mezhov, Leonid Mylnikov
doaj   +1 more source

Quasi-Multipliers [PDF]

open access: yesTransactions of the American Mathematical Society, 1977
A quasi-multiplier m on an algebra A is a bilinear mapping from A × A A \times A into itself such that m ( a x , y b ) = a m ( x , y ) b m(ax,yb) = am(x,y)b for all a
openaire   +2 more sources

Impact of Asymptomatic Intracranial Hemorrhage on Outcome After Endovascular Stroke Treatment

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Endovascular treatment (EVT) achieves high rates of recanalization in acute large‐vessel occlusion (LVO) stroke, but functional recovery remains heterogeneous. While symptomatic intracranial hemorrhage (sICH) has been well studied, the prognostic impact of asymptomatic intracranial hemorrhage (aICH) after EVT is less certain ...
Shihai Yang   +22 more
wiley   +1 more source

Low Voltage High Performance CMOS Current Mode Four-Quadrant Analog Multiplier Circuit [PDF]

open access: yesRadioengineering, 2022
This paper describes a new CMOS current mode four-quadrant analog multiplier circuit. The proposed design is based on a high performance squarer cell, whose main core is realized by the up–down topology trans-linear loop using flipped voltage followers ...
T. Ettaghzouti   +3 more
doaj  

Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher   +10 more
wiley   +1 more source

Design and Implementation of a New Frequency Synthesizer for Rubidium Atomic Frequency Standard

open access: yesChinese Journal of Magnetic Resonance, 2017
Progresses have been made in the development of digitalized and miniaturized rubidium atomic frequency standard (RAFS). In the traditional RAFS circuits, the 6 840 MHz microwave signal is mixed with the 5.312 5 MHz signal generated by the frequency ...
HUANG Zheng   +3 more
doaj   +1 more source

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