Results 201 to 210 of about 73,884 (236)

The many faces of the GID/CTLH E3 ligase complex. [PDF]

Biochem Soc Trans
Alpi AF, Chrustowicz J, Sherpa D, Schulman BA.   +3 more
europepmc   +1 more source

The Allosteric Regulator Inositol Phosphate Dramatically Affects the Efficacy and Selectivity of Inhibitors for Different HDAC Complexes. [PDF]

J Am Chem Soc
Pytel WA, Patel U, Smalley JP, Millard CJ, Brown EA, Pavan AR, Wang S, Kalin JH, Dos Santos JL, Cole PA, Hodgkinson JT, Schwabe JWR.   +11 more
europepmc   +1 more source

Cellular Target Engagement and Dissociation Kinetics of Class I-Selective Histone Deacetylase (HDAC) Inhibitors. [PDF]

Int J Mol Sci
Honin I, Novakova Z, Feller F, Schneider S, Schäker-Hübner L, Barinka C, K Hansen F.   +6 more
europepmc   +1 more source

Subcellular targeting of survivin peptides: A multi-axis approach to cancer therapy. [PDF]

Mol Ther Oncol
Pathania AS.
europepmc   +1 more source

FcR γ-chain and platelet hyperactivity. [PDF]

Blood Adv
Silverstein RL.
europepmc   +1 more source

[Rearrangement of chromatin structure by multiprotein complexes].

Postepy biochemii, 2002
openaire   +1 more source

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ACEMBLing a Multiprotein Transmembrane Complex

Nature Methods, 2015
Structural and functional studies of many multiprotein complexes depend on recombinant-protein overexpression. Rapid revision of expression experiments and diversification of the complexes are often crucial for success of these projects; therefore, automation is increasingly indispensable.
Joanna Komar, Mathieu Botte, Ian Collinson, Christiane Schaffitzel, Imre Berger   +4 more
openaire   +4 more sources

Multiprotein complexes governing Wnt signal transduction

Current Opinion in Cell Biology, 2018
Three multiprotein complexes have key roles in transducing Wnt signals from the plasma membrane to the cell nucleus - the β-catenin destruction complex, or Axin degradasome, which targets the Wnt effector β-catenin for proteasomal degradation in the absence of Wnt; the Wnt signalosome, assembled by polymerization of Dishevelled upon Wnt engaging its ...
Melissa, Gammons, Mariann, Bienz
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Multiprotein complex signaling and the plasticity problem

Current Opinion in Neurobiology, 2001
Synaptic transmission of distinct patterns of spikes, or 'neural code', leads to plastic changes in synapses and other parts of the neuron, as well as learning in animals. Recent findings indicate that specialized multiprotein structures associated with neurotransmitter receptors and cell-adhesion proteins function as molecular devices that both read ...
S G, Grant, T J, O'Dell
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Baculovirus expression system for heterologous multiprotein complexes

Nature Biotechnology, 2004
The discovery of large multiprotein complexes in cells has increased the demand for improved heterologous protein production techniques to study their molecular structure and function. Here we describe MultiBac, a simple and versatile system for generating recombinant baculovirus DNA to express protein complexes comprising many subunits.
Imre, Berger, Daniel J, Fitzgerald, Timothy J, Richmond   +2 more
openaire   +2 more sources