Results 161 to 170 of about 20,135,100 (276)

Time-space multiscale model for viscoelastic construction materials using the initial stress method. [PDF]

iScience
Wang X, Wang Y, Qiang H, Bai J, Zhao Z, Hou X.   +5 more
europepmc   +1 more source

GlycoMAC: A Multiscale Metabolic‐Glycosylation Framework for Predicting Glycosylation Across Conditions in Mammalian Cell Cultures

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Antibody productivity and glycosylation quality in CHO cell cultures emerge from a dynamically evolving metabolic environment, yet existing models often work in isolation or at a single scale. Here, we present a multiscale mechanistic framework linking molecular, cellular, and macroscopic scales to predict how inputs shape bioprocess ...
Yuming Zeng, Sarah W. Harcum, Jinxiang Pei, Wei Xie   +3 more
wiley   +1 more source

A multiscale confocal-finite element method to relate single-osteocyte Wnt/β-catenin activation to lacunar wall strain in murine cortical bone. [PDF]

JBMR Plus
Laughrey LE, Lara-Castillo N, Xie Y, Scott J, Moore D, Dallas MR, Dallas SL, Johnson ML, Ganesh T.   +8 more
europepmc   +1 more source

Nacre‐inspired layered composite with excellent mechanical support and osteogenic potential for cervical interbody cage

BMEMat, EarlyView.
The cervical interbody cage needs to take both biomechanical and biological requirements into account. Here, a new‐style degradable, multicomponent, and bioinspired nacre‐like cervical interbody cage composite, which exhibits promising mechanical‐support‐related behavior and osteogenesis‐related potential, is designed and prepared.
Xiu‐Wu Guo, Shao‐Meng Wen, Tian‐Yu Xing, Yang Zhou, Chun‐Xin Wang, Chang Ge, Si‐Ming Chen, Wen‐Zhi Zhang, Shu‐Hong Yu   +8 more
wiley   +1 more source

Acoustic-Emission-Based Multiscale Tensile Constitutive Model for Ultra-High-Performance Concrete Considering Steel-Fiber Parameters and Beam-Scale Validation. [PDF]

Materials (Basel)
Bao Z, Wang Q, Deng J, Zhang M.
europepmc   +1 more source

Restoring joint homeostasis: A dynamically adaptive meniscal scaffold prevents osteoarthritis by replicating native biomechanics

BMEMat, EarlyView.
This work establishes a paradigm shift from static structural mimicry to dynamic functional replication. By restoring the native “compression‐to‐tension” mechanism, the scaffold ensures robust mechanical stability and superior chondroprotection.
Wan Li, Moran Huang, Dongsen Jia, Yongjie Jiao, Jize Dong, Fujun Wang, Xinhou Wang, Jiwu Chen, Malcolm Xing, Lu Wang, Chaojing Li   +10 more
wiley   +1 more source

Recent Advances in Performance-Driven Multiscale Strategies for Epoxy-Based Underfill Materials for Advanced Packaging. [PDF]

Polymers (Basel)
Wang Y, Wang Y, Wu Y, Yan Y, Li Y, Sun D, Xie A.   +6 more
europepmc   +1 more source

From muscle fibres to muscle gears: how dynamic fascicle orientation and shape change impact skeletal muscle function

Biological Reviews, EarlyView.
ABSTRACT Skeletal muscle architectural design strongly affects force‐generating capacity and excursion range, and its functional importance to animal and human movement is well founded. Traditionally, this ‘structure–function relation’ has been inferred from architecture measurements with muscles at rest (from anatomical dissections or medical imaging ...
Matheus D. Pinto, James M. Wakeling, Javier A. Almonacid, Anthony J. Blazevich   +3 more
wiley   +1 more source

Strong acoustic meta-aerogels enabled by nanoconfined directional freezing and in-situ polymerization. [PDF]

Nat Commun
Wang J, Wu Z, Huang W, Zhou A, Zhuo J, Yu Y, Miao C, Lu MH, She W.   +8 more
europepmc   +1 more source

Electrospun Porous Materials for the Next‐Generation Proton Exchange Membrane Fuel Cells: Progress, Challenges, and AI‐Optimized Perspectives

Carbon Energy, EarlyView.
Incorporating AI to optimize solution, process, and environment enables efficient prediction of structural properties and performance, allowing tailoring of GDL, CL, and PEM fabrication to guide PEMFC toward 9.0 kW L‒1 by 2040. ABSTRACT The performance and commercial viability of proton exchange membrane fuel cells (PEMFCs) are constrained by key ...
Shangfeng Jiang, Panfeng Wang, You Gong, Zeyu Sun, Huatan Chen, Geng Wang, Ting Tao, Chuang Zhai, Xi Wang, Ruixin Chen, Jiaxin Jiang, Bingrong Zhang   +11 more
wiley   +1 more source