Results 21 to 30 of about 1,095 (141)

Use of Multispectral Optoacoustic Tomography to Diagnose Vascular Malformations

JAMA Dermatology, 2018
Differential diagnosis of congenital vascular anomalies is challenging, and misdiagnosis is frequent. Vascular malformations are considered one of the most difficult vascular diseases to treat. A new imaging approach that visualizes anatomical features and quantitatively assesses molecular biomarkers noninvasively would aid diagnosis and monitoring of ...
Masthoff, M., Helfen, A., Claussen, J., Karlas, A., Markwardt, N.A., Ntziachristos, V., Eisenblätter, M., Wildgruber, M.   +7 more
openaire   +5 more sources

VEGF-Targeted Multispectral Optoacoustic Tomography and Fluorescence Molecular Imaging in Human Carotid Atherosclerotic Plaques [PDF]

Diagnostics, 2021
Vulnerable atherosclerotic carotid plaques are prone to rupture, resulting in ischemic strokes. In contrast to radiological imaging techniques, molecular imaging techniques have the potential to assess plaque vulnerability by visualizing diseases ...
Pieter J. Steinkamp, Jasper Vonk, Lydian A. Huisman, Gert-Jan Meersma, Gilles F. H. Diercks, Jan-Luuk Hillebrands, Wouter B. Nagengast, Clark J. Zeebregts, Riemer H. J. A. Slart, Hendrikus H. Boersma, Gooitzen M. van Dam   +10 more
doaj   +2 more sources

Multispectral Optoacoustic Tomography of Benign and Malignant Thyroid Disorders: A Pilot Study [PDF]

Journal of Nuclear Medicine, 2019
This study aimed at evaluating hybrid multispectral optoacoustic tomography/ultrasound for imaging of thyroid disorders, including Graves' disease and thyroid nodules. Methods: The functional biomarkers and tissue parameters deoxygenated hemoglobin, oxygenated hemoglobin, total hemoglobin, saturation of hemoglobin, fat content, and water content were ...
Roll, W., Markwardt, N.A., Masthoff, M., Helfen, A., Claussen, J., Eisenblätter, M., Hasenbach, A., Hermann, S., Karlas, A., Wildgruber, M., Ntziachristos, V., Schäfers, M.   +11 more
openaire   +4 more sources

Application of multispectral optoacoustic tomography for lower limb musculoskeletal sports injuries in adults [PDF]

Photoacoustics
Compositional changes in relation to musculoskeletal injuries are difficult to measure non-invasively. This study aims to use non-invasive label-free imaging with Multispectral Optoacoustic Tomography (MSOT) to evaluate compositional changes with injury.
Rene B. Svensson, Anne-Sofie Agergaard, Thomas Sardella, Charlène Reichl, Mikkel H. Hjortshoej, Monika L. Bayer, Rikke Hoeffner, Christian Couppé, Michael Kjaer, S. Peter Magnusson   +9 more
doaj   +2 more sources

Assessment of Breast Tumors Using Multispectral Optoacoustic Tomography in a Surgical Setting [PDF]

Journal of Nuclear Medicine
In breast-conserving surgery, wire or seed localization and ultrasound are limited by lack of margin detection and contrast imaging, respectively. Handheld multispectral optoacoustic tomography (MSOT) allows for contrast imaging using endogenous or exogenous agents.
McNally, Lacey R., Claros-Sorto, Juan Carlos, Bynum, Ryan C., Grizzle, William E., Han, Zheng, Squires, Ronald, Tippetts, Jacob D., Brannen, Andrew, Garwe, Tabitha, Cohoon, Andrew, Edil, Barish H., Holter-Chakrabarty, Jennifer, Jain, Ajay   +12 more
openaire   +3 more sources

Multispectral Optoacoustic Tomography Enables In Vivo Anatomical and Functional Assessment of Human Tendons [PDF]

Advanced Science
Tendon injuries resulting from accidents and aging are increasing globally. However, key tendon functional parameters such as microvascularity and oxygen perfusion remain inaccessible via the currently available clinical diagnostic tools, resulting in ...
Ivana Ivankovic, Hsiao‐Chun Amy Lin, Ali Özbek, Ana Orive, Xosé Luís Deán‐Ben, Daniel Razansky   +5 more
doaj   +2 more sources

Unmixing Molecular Agents From Absorbing Tissue in Multispectral Optoacoustic Tomography

IEEE Transactions on Medical Imaging, 2014
Detection of intrinsic or extrinsically administered chromophores and photo-absorbing nanoparticles has been achieved by multi-spectral optoacoustic tomography (MSOT). The detection sensitivity of MSOT depends not only on the signal to noise ratio considerations, as in conventional optoacoustic (photoacoustic) tomography implementations, but also on ...
Stratis Tzoumas, Nikolaos Deliolanis, Stefan Morscher   +2 more
exaly   +3 more sources

Multispectral optoacoustic tomography of benign parotid tumors in vivo: a prospective observational pilot study [PDF]

Scientific Reports
Parotid lumps are a heterogeneous group of mainly benign but also malignant tumors. Preoperative imaging does not allow a differentiation between tumor types. Multispectral optoacoustic tomography (MSOT) may improve the preoperative diagnostics.
Mussab Kouka, Maximilian Waldner, Orlando Guntinas-Lichius   +2 more
doaj   +2 more sources

A sparse deep learning approach for automatic segmentation of human vasculature in multispectral optoacoustic tomography [PDF]

Photoacoustics, 2020
Multispectral Optoacoustic Tomography (MSOT) resolves oxy- (HbO2) and deoxy-hemoglobin (Hb) to perform vascular imaging. MSOT suffers from gradual signal attenuation with depth due to light-tissue interactions: an effect that hinders the precise manual ...
Nikolaos-Kosmas Chlis, Angelos Karlas, Nikolina-Alexia Fasoula, Michael Kallmayer, Hans-Henning Eckstein, Fabian J. Theis, Vasilis Ntziachristos, Carsten Marr   +7 more
doaj   +2 more sources

Spotlight on Nerves: Portable Multispectral Optoacoustic Imaging of Peripheral Nerve Vascularization and Morphology

Advanced Science, 2023
Various morphological and functional parameters of peripheral nerves and their vascular supply are indicative of pathological changes due to injury or disease.
Dominik Jüstel, Hedwig Irl, Florian Hinterwimmer, Christoph Dehner, Walter Simson, Nassir Navab, Gerhard Schneider, Vasilis Ntziachristos   +7 more
doaj   +1 more source