Results 41 to 50 of about 1,095 (141)

In vivo tracking of orally-administered particles within the gastrointestinal tract of murine models using multispectral optoacoustic tomography

Photoacoustics, 2019
While particle carriers have potential to revolutionize disease treatment, using these carriers requires knowledge of spatial and temporal biodistribution.
Neal Bhutiani, Abhilash Samykutty, Kelly M. McMasters, Nejat K. Egilmez, Lacey R. McNally   +4 more
doaj   +1 more source

Multispectral Optoacoustic Tomography (MSOT) of Human Breast Cancer [PDF]

Clinical Cancer Research, 2017
Abstract Purpose: In a pilot study, we introduce fast handheld multispectral optoacoustic tomography (MSOT) of the breast at 28 wavelengths, aiming to identify high-resolution optoacoustic (photoacoustic) patterns of breast cancer and noncancerous breast tissue.
Diot, G., Metz, S., Noske, A., Liapis, E., Schroeder, B., Ovsepian, S.V., Meier, R., Rummeny, E.J., Ntziachristos, V.   +8 more
openaire   +3 more sources

Multispectral Optoacoustic Tomography of Brown Adipose Tissue

, 2018
MSOT has revolutionized biomedical imaging because it allows anatomical, functional, and molecular imaging of deep tissues in vivo in an entirely noninvasive, label-free, and real-time manner. This imaging modality works by pulsing light onto tissue, triggering the production of acoustic waves, which can be collected and reconstructed to provide high ...
Karlas, A., Reber, J., Liapis, E., Paul-Yuan, K., Ntziachristos, V.   +4 more
openaire   +4 more sources

Teachability of multispectral optoacoustic tomography

Journal of Biophotonics
AbstractTo date, the appropriate training required for the reproducible operation of multispectral optoacoustic tomography (MSOT) is poorly discussed. Therefore, the aim of this study was to assess the teachability of MSOT imaging. Five operators (two experienced and three inexperienced) performed repositioning imaging experiments.
Yi Li, Janek Gröhl, Briain Haney, Milenko Caranovic, Eva Lorenz‐Meyer, Nikolaos Papatheodorou, Julius Kempf, Adrian P. Regensburger, Emmanuel Nedoschill, Adrian Buehler, Gregor Siebenlist, Werner Lang, Michael Uder, Markus F. Neurath, Maximilian Waldner, Ferdinand Knieling, Ulrich Rother   +16 more
openaire   +3 more sources

Development of amyloid beta gold nanorod aggregates as optoacoustic probes.

PLoS ONE, 2022
Propagation of small amyloid beta (Aβ) aggregates (or seeds) has been suggested as a potential mechanism of Alzheimer's disease progression. Monitoring the propagation of Aβ seeds in an organism would enable testing of this hypothesis and, if confirmed ...
Mahmoud G Soliman, Hannah A Davies, Jack Sharkey, Raphaël Lévy, Jillian Madine   +4 more
doaj   +1 more source

Multimodal cell tracking from systemic administration to tumour growth by combining gold nanorods and reporter genes

eLife, 2018
Understanding the fate of exogenous cells after implantation is important for clinical applications. Preclinical studies allow imaging of cell location and survival.
Joan Comenge, Jack Sharkey, Oihane Fragueiro, Bettina Wilm, Mathias Brust, Patricia Murray, Raphael Levy, Antonius Plagge   +7 more
doaj   +1 more source

Longitudinal Assessment of Muscle Involvement in Late‐Onset Pompe Disease Using Quantitative MRI: A Prospective Cohort Study

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 3, June 2026.
ABSTRACT Background Late‐onset Pompe disease (LOPD) is a progressive metabolic myopathy characterised by lysosomal glycogen accumulation and leading to secondary disruptions in autophagy and cellular energy metabolism. While enzyme replacement therapy (ERT) has improved outcomes, early detection remains critical, because irreversible muscle damage ...
Alice De Lorenzo, Johannes Forsting, Martijn Froeling, Anne‐Katrin Güttsches, Elena Enax‐Krumova, Felix Kleefeld, Menekse Öztürk, Ferdinand Knieling, Matthias Vorgerd, Robert Rehmann, Tobias Ruck, Lara Schlaffke   +11 more
wiley   +1 more source

Fluorescent proteins: A journey from the cell to extreme environments in material science

Photochemistry and Photobiology, Volume 102, Issue 2, Page 290-302, March/April 2026.
Applications of proteins and microorganisms as tools or effectors in material science. Abstract This review presents the progression from the use of fluorescent proteins (FPs) and chromoproteins as bioimaging labels and sensors to the strategic engineering of their properties for robust functionality in synthetic and non‐biological environments ...
Bianca Menchicchi, Andre C. Stiel, Mattia Nieddu, J. P. Fuenzalida‐Werner   +3 more
wiley   +1 more source

Multispectral optoacoustic tomography at 64, 128, and 256 channels

Journal of Biomedical Optics, 2014
Optoacoustic (photoacoustic) imaging has already showcased the capacity to offer high-resolution small animal visualization in vivo in a variety of cancer, cardiovascular, or neuroimaging applications. In particular, multispectral optoacoustic tomography (MSOT) has shown imaging along the spectral and the time dimensions, enabling sensing of multiple ...
Dima A, Burton NC, Ntziachristos V.
openaire   +3 more sources

Cold Quad‐Modal Nanocomplex for Precise and Quantitative In Vivo Stem Cell Tracking

Advanced Functional Materials, Volume 36, Issue 17, 26 February 2026.
Multimodal albumin–bismuth sulfide–superparamagnetic iron oxide (ABS) nanocomplexes are developed for stem cell tracking across four different imaging modalities: MRI, MPI, MSOT, and CT. Combining its flexibility with high sensitivity, this quad‐modal imaging agent enables a robust quantification of ABS‐labeled stem cells in vivo.
Ali Shakeri‐Zadeh, Chao Wang, Shreyas Kuddannaya, Saleem Yousf, Jeff W. M. Bulte   +4 more
wiley   +1 more source