Multispectral Optoacoustic Tomography (MSOT) Characterization in Resolving Molecular Biomarkers
Fluorochromes are essential biological reporters in many areas of biomedical research and, in particular, molecular imaging applications. We demonstrate the basic performance characteristics of multispectral optoacoustic tomography in resolving fluorochromes in tissue-mimicking phantoms.
Taruttis, A. +4 more
openaire +3 more sources
Multispectral Optoacoustic Tomography Enables In Vivo Anatomical and Functional Assessment of Human Tendons [PDF]
Tendon injuries resulting from accidents and aging are increasing globally. However, key tendon functional parameters such as microvascularity and oxygen perfusion remain inaccessible via the currently available clinical diagnostic tools, resulting in ...
Ivana Ivankovic +5 more
doaj +2 more sources
Volumetric real-time multispectral optoacoustic tomography of biomarkers
Multispectral optoacoustic tomography (MSOT) has recently been developed to enable visualization of optical contrast and tissue biomarkers, with resolution and speed representative of ultrasound. In the implementation described here, MSOT enables operation in real-time mode by capturing single cross-sectional images in
Daniel Razansky +2 more
openaire +3 more sources
Multispectral optoacoustic tomography at 64, 128, and 256 channels
Optoacoustic (photoacoustic) imaging has already showcased the capacity to offer high-resolution small animal visualization in vivo in a variety of cancer, cardiovascular, or neuroimaging applications. In particular, multispectral optoacoustic tomography (MSOT) has shown imaging along the spectral and the time dimensions, enabling sensing of multiple ...
Dima A, Burton NC, Ntziachristos V.
core +5 more sources
Multispectral Optoacoustic Tomography of Skeletal Muscle Unveils Microcirculation and Oxygen Metabolism Alterations in Sarcopenia [PDF]
Background Sarcopenia, a significant geriatric syndrome, faces challenges in accurate diagnosis due to limitations of current imaging techniques. This study explores the novel application of multispectral optoacoustic tomography (MSOT) in evaluating ...
Ying Yang +18 more
doaj +2 more sources
Multispectral optoacoustic tomography of benign parotid tumors in vivo: a prospective observational pilot study [PDF]
Parotid lumps are a heterogeneous group of mainly benign but also malignant tumors. Preoperative imaging does not allow a differentiation between tumor types. Multispectral optoacoustic tomography (MSOT) may improve the preoperative diagnostics.
Mussab Kouka +2 more
doaj +2 more sources
Evaluation of cervical lymph nodes using multispectral optoacoustic tomography: a proof-of-concept study. [PDF]
ObjectivesExamination of lymph nodes is one of the most common indications for imaging in the head and neck region. The purpose of this study is to evaluate whether multispectral optoacoustic tomography can be used to observe chromophore differences ...
Becker C +9 more
europepmc +2 more sources
Various morphological and functional parameters of peripheral nerves and their vascular supply are indicative of pathological changes due to injury or disease.
Dominik Jüstel +7 more
doaj +1 more source
Croconaine-based nanoparticles enable efficient optoacoustic imaging of murine brain tumors
Contrast enhancement in optoacoustic (photoacoustic) imaging can be achieved with agents that exhibit high absorption cross-sections, high photostability, low quantum yield, low toxicity, and preferential bio-distribution and clearance profiles. Based on
Nian Liu +17 more
doaj +1 more source
Optical Imaging of Cancer Heterogeneity with Multispectral Optoacoustic Tomography [PDF]
To investigate whether multispectral optoacoustic tomography (MSOT) can reveal the heterogeneous distributions of exogenous agents of interest and vascular characteristics through tumors of several millimeters in diameter in vivo.Procedures involving animals were approved by the government of Upper Bavaria.
Eva Herzog +5 more
openaire +2 more sources

