Results 31 to 40 of about 1,095 (141)

Croconaine-based nanoparticles enable efficient optoacoustic imaging of murine brain tumors

Photoacoustics, 2021
Contrast enhancement in optoacoustic (photoacoustic) imaging can be achieved with agents that exhibit high absorption cross-sections, high photostability, low quantum yield, low toxicity, and preferential bio-distribution and clearance profiles. Based on
Nian Liu, Vipul Gujrati, Jaber Malekzadeh-Najafabadi, Juan Pablo Fuenzalida Werner, Uwe Klemm, Longguang Tang, Zhenyue Chen, Jaya Prakash, Yuanhui Huang, Andre Stiel, Gabriele Mettenleiter, Michaela Aichler, Andreas Blutke, Axel Walch, Karin Kleigrewe, Daniel Razansky, Michael Sattler, Vasilis Ntziachristos   +17 more
doaj   +1 more source

Constrained Inversion and Spectral Unmixing in Multispectral Optoacoustic Tomography [PDF]

IEEE Transactions on Medical Imaging, 2017
Accurate extraction of physical and biochemical parameters from optoacoustic images is often impeded due to the use of unrigorous inversion schemes, incomplete tomographic detection coverage, or other experimental factors that cannot be readily accounted for during the image acquisition and reconstruction process.
Lu Ding, X. Luís Dean-Ben, Neal C. Burton, Robert W. Sobol, Vasilis Ntziachristos, Daniel Razansky   +5 more
openaire   +4 more sources

Intravascular multispectral optoacoustic tomography of atherosclerosis: prospects and challenges [PDF]

Imaging in Medicine, 2012
The progression of atherosclerosis involves complex changes in the structure, composition and biology of the artery wall. Currently, only anatomical plaque burden is routinely characterized in living patients, whereas compositional and biological changes are mostly inaccessible.
Amir Rosenthal, Farouc A Jaffer, Vasilis Ntziachristos   +2 more
openaire   +2 more sources

Photoacoustic temperature imaging based on multi-wavelength excitation

Photoacoustics, 2019
Building further upon the high spatial resolution offered by ultrasonic imaging and the high optical contrast yielded by laser excitation of photoacoustic imaging, and exploiting the temperature dependence of photoacoustic signal amplitudes, this paper ...
Lei Meng, Olivier Deschaume, Lionel Larbanoix, Eduard Fron, Carmen Bartic, Sophie Laurent, Mark Van der Auweraer, Christ Glorieux   +7 more
doaj   +1 more source

Spatial and Spectral Mapping and Decomposition of Neural Dynamics and Organization of the Mouse Brain with Multispectral Optoacoustic Tomography

Cell Reports, 2019
Summary: In traditional optical imaging, limited light penetration constrains high-resolution interrogation to tissue surfaces. Optoacoustic imaging combines the superb contrast of optical imaging with deep penetration of ultrasound, enabling a range of ...
Ivan Olefir, Ara Ghazaryan, Hong Yang, Jaber Malekzadeh-Najafabadi, Sarah Glasl, Panagiotis Symvoulidis, Valerie B. O’Leary, George Sergiadis, Vasilis Ntziachristos, Saak V. Ovsepian   +9 more
doaj   +1 more source

Multispectral optoacoustic tomography of myocardial infarction

Photoacoustics, 2013
To investigate the feasibility of a high resolution optical imaging strategy for myocardial infarction.Near-infrared approaches to imaging cardiovascular disease enable visualization of disease-associated biological processes in vivo. However, even at the scale of small animals, the strong scattering of light prevents high resolution imaging after the ...
Taruttis, Adrian, Wildgruber, Moritz, Kosanke, Katja, Beziere, Nicolas, Licha, Kai, Haag, Rainer, Aichler, Michaela, Walch, Axel, Rummeny, Ernst, Ntziachristos, Vasilis   +9 more
openaire   +2 more sources

Optical Imaging of Cancer Heterogeneity with Multispectral Optoacoustic Tomography [PDF]

Radiology, 2012
To investigate whether multispectral optoacoustic tomography (MSOT) can reveal the heterogeneous distributions of exogenous agents of interest and vascular characteristics through tumors of several millimeters in diameter in vivo.Procedures involving animals were approved by the government of Upper Bavaria.
Eva Herzog, Adrian Taruttis, Nicolas Beziere, Andrey A. Lutich, Daniel Razansky, Vasilis Ntziachristos   +5 more
openaire   +2 more sources

Hand-held optoacoustic imaging: A review

Photoacoustics, 2018
Optoacoustic imaging is a medical imaging modality that uses optical excitation and acoustic detection to generate images of tissue structures based up optical absorption within a tissue sample.
Mason W. Schellenberg, Heather K. Hunt
doaj   +1 more source

Noninvasive Imaging of Colitis Using Multispectral Optoacoustic Tomography [PDF]

Journal of Nuclear Medicine, 2016
Currently, several noninvasive modalities, including MRI and PET, are being investigated to identify early intestinal inflammation, longitudinally monitor disease status, or detect dysplastic changes in patients with inflammatory bowel disease. Here, we assess the applicability and utility of multispectral optoacoustic tomography (MSOT) in evaluating ...
Neal, Bhutiani, William E, Grizzle, Susan, Galandiuk, Denis, Otali, Gerald W, Dryden, Nejat K, Egilmez, Lacey R, McNally   +6 more
openaire   +2 more sources

Eigenspectra optoacoustic tomography achieves quantitative blood oxygenation imaging deep in tissues

Nature Communications, 2016
Spectral corruption impedes imaging of blood oxygen saturation. Here Tzoumas et al.describe light fluence in the spectral domain and introduce eigenspectra Multispectral Optoacoustic Tomography to account for wavelength-dependent light attenuation and ...
Stratis Tzoumas, Antonio Nunes, Ivan Olefir, Stefan Stangl, Panagiotis Symvoulidis, Sarah Glasl, Christine Bayer, Gabriele Multhoff, Vasilis Ntziachristos   +8 more
doaj   +1 more source