Results 81 to 90 of about 668,228 (165)

Performance of a Multispectral Optoacoustic Tomography (MSOT) System equipped with 2D vs. 3D Handheld Probes for Potential Clinical Translation

Photoacoustics, 2016
A handheld approach to optoacoustic imaging is essential for the clinical translation. The first 2- and 3-dimensional handheld multispectral optoacoustic tomography (MSOT) probes featuring real-time unmixing have recently been developed.
Volker Neuschmelting, Neal C. Burton, Hannah Lockau, Alexander Urich, Stefan Harmsen, Vasilis Ntziachristos, Moritz F. Kircher   +6 more
doaj   +1 more source

Surface‐Enhanced Raman Scattering‐Based Multimodal Medical Imaging in Cancer Diagnosis and Therapy Monitoring

Rare Metals, Volume 45, Issue 10, October 2026.
ABSTRACT Surface‐enhanced Raman scattering (SERS) has emerged as a highly sensitive and specific technique for tumor imaging, owing to its narrow spectral features, resistance to photobleaching, and capability for multiplexed detection. However, its clinical translation remains limited by poor tissue penetration and the absence of intrinsic anatomical ...
Xinyu Miao, Yujiao Xie, Aochi Liu, Shishuai Zheng, Dong Xu, Aiguo Wu, Jie Lin, Xiaoxia Wu   +7 more
wiley   +1 more source

Volumetric optoacoustic tomography of deep tissue morphology and function in real time.

, 2013
In this work we demonstrate a multispectral optoacoustic tomography system capable of real-time three-dimensional optoacoustic imaging of intrinsic anatomical and functional contrast as well as extrinsically-administered bio-markers in deep ...
Bühler, A., X Luis Dean-Ben, Vasilis Ntziachristos, Razansky, D., Dean-Ben, X.L., Daniel Razansky, Andreas Buehler, Ntziachristos, V.   +7 more
core   +1 more source

MSOT-RAFT: A Reconstruction, Analysis, and Filtering Toolbox for Multispectral Optoacoustic Tomography data.

, 2021
This is the alpha upload of the MSOT Reconstruction, Analysis, and Filtering Toolbox. Please cite us if you use or refer to this software. O’Kelly, D., Campbell, J., Gerberich, J.L. et al.
Devin O'Kelly
core   +1 more source

Non‐invasive Imaging Modalities for Breslow Thickness Estimation in Melanoma: A Scoping Review

Skin Research and Technology, Volume 32, Issue 10, October 2026.
ABSTRACT Background Breslow thickness (BT) is the most important prognostic biomarker in cutaneous melanoma and directly influences surgical management, sentinel lymph node biopsy decisions and survival outcomes. Several non‐invasive imaging modalities have been investigated for preoperative BT estimation; however, their relative performance and ...
Biagio Scotti, Martina Lambertini, Leonardo Veneziano, Federico Venturi, Elisabetta Magnaterra, Carlotta Baraldi, Emi Dika   +6 more
wiley   +1 more source

Hybrid multispectral optoacoustic and ultrasound tomography for morphological and physiological brain imaging [PDF]

Journal of Biomedical Optics, 2016
Expanding usage of small animal models in biomedical research necessitates development of technologies for structural, functional, or molecular imaging that can be readily integrated in the biological laboratory. Herein, we consider dual multispectral optoacoustic (OA) and ultrasound tomography based on curved ultrasound detector arrays and describe ...
Olefir, Ivan, Mercep, Elena, Burton, Neal C., Ovsepian, Saak V., Ntziachristos, Vasilis   +4 more
openaire   +3 more sources

Longitudinal Assessment of Muscle Involvement in Late‐Onset Pompe Disease Using Quantitative MRI: A Prospective Cohort Study

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 3, June 2026.
ABSTRACT Background Late‐onset Pompe disease (LOPD) is a progressive metabolic myopathy characterised by lysosomal glycogen accumulation and leading to secondary disruptions in autophagy and cellular energy metabolism. While enzyme replacement therapy (ERT) has improved outcomes, early detection remains critical, because irreversible muscle damage ...
Alice De Lorenzo, Johannes Forsting, Martijn Froeling, Anne‐Katrin Güttsches, Elena Enax‐Krumova, Felix Kleefeld, Menekse Öztürk, Ferdinand Knieling, Matthias Vorgerd, Robert Rehmann, Tobias Ruck, Lara Schlaffke   +11 more
wiley   +1 more source

High-contrast imaging of reversibly switchable fluorescent proteins via temporally unmixed multispectral optoacoustic tomography.

, 2015
Photocontrol of reversibly switchable fluorescent proteins (RSFPs) was used to program optoacoustic signal time courses that were temporally unmixed to increase the proteins' contrast-to-noise-ratios (CNRs) in optoacoustic imaging.
Stiel, Andre C;Deán-Ben, Xosé Luís;Jiang, Yuanyuan;Ntziachristos, Vasilis;Razansky, Daniel;Westmeyer, Gil G
core   +3 more sources

Fluorescent proteins: A journey from the cell to extreme environments in material science

Photochemistry and Photobiology, Volume 102, Issue 2, Page 290-302, March/April 2026.
Applications of proteins and microorganisms as tools or effectors in material science. Abstract This review presents the progression from the use of fluorescent proteins (FPs) and chromoproteins as bioimaging labels and sensors to the strategic engineering of their properties for robust functionality in synthetic and non‐biological environments ...
Bianca Menchicchi, Andre C. Stiel, Mattia Nieddu, J. P. Fuenzalida‐Werner   +3 more
wiley   +1 more source

Multispectral optoacoustic tomography resolves smart probe activation in vulnerable plaques.

, 2011
In this work, we show, for the first time to our knowledge, that multispectral optoacoustic tomography (MSOT) can deliver high resolution images of activatable molecular probe's distribution, sensitive to matrix metalloproteinases (MMP), deep within ...
Razansky, Daniel, Jan-Luuk Hillebrands, Hillebrands, J.-L., van Dam, G.M., Harlaar, Niels J., Zeebregts, C.J., Clark Zeebregts, Hillebrands, Jan Luuk; id_orcid, Taruttis, A., Harlaar, N.J., Taruttis, Adrian, Goitzen van Dam, Zeebregts, Clark, Ntziachristos, V., Van Dam, Goitzen, Ntziachristos, Vasilis, Adrian Taruttis, Herzog, E., Niels J. Harlaar, Vasilis Ntziachristos, Herzog, Eva, Razansky, D., Daniel Razansky, Eva Herzog   +23 more
core   +1 more source