Results 71 to 80 of about 1,095 (141)

Multiscale Multispectral Optoacoustic Tomography by a Stationary Wavelet Transform Prior to Unmixing

IEEE Transactions on Medical Imaging, 2014
Multispectral optoacoustic tomography (MSOT) utilizes broadband ultrasound detection for imaging biologically-relevant optical absorption features at a range of scales. Due to the multiscale and multispectral features of the technology, MSOT comes with distinct requirements in implementation and data analysis. In this work, we investigate the interplay
Adrian Taruttis, Amir Rosenthal, Marcin Kacprowicz, Neal C. Burton, Vasilis Ntziachristos   +4 more
openaire   +3 more sources

Real‐Time Monitoring of Atherosclerotic Plaque Using β‐Galactosidase‐Activated Photoacoustic Tomography

Small, Volume 21, Issue 44, November 6, 2025.
Detecting Vascular Senescence: Novel Enzyme‐Responsive Photoacoustic Nanoprobes for Atherosclerotic Plaque Imaging. A lipid nanoprobe is developed that detects senescence‐associated β‐galactosidase in plaques via enzyme‐triggered spectral shifts. This platform enables dynamic tracking of atherosclerotic progression, 3D visualization on the extent and ...
Yifan Zhou, Hang Yang, Handi Deng, Feng Zhang, Junjie Jiang, Sibo Yang, Xiaodi Sun, Jiehong Wu, Yanan Li, Huijuan Jin, Hao Wang, Cheng Ma, Li‐Li Li, Bo Hu   +13 more
wiley   +1 more source

Hybrid multispectral optoacoustic and ultrasound tomography for morphological and physiological brain imaging [PDF]

Journal of Biomedical Optics, 2016
Expanding usage of small animal models in biomedical research necessitates development of technologies for structural, functional, or molecular imaging that can be readily integrated in the biological laboratory. Herein, we consider dual multispectral optoacoustic (OA) and ultrasound tomography based on curved ultrasound detector arrays and describe ...
Olefir, Ivan, Mercep, Elena, Burton, Neal C., Ovsepian, Saak V., Ntziachristos, Vasilis   +4 more
openaire   +3 more sources

Breaking (Light) Barriers: Photoacoustics in Atherosclerotic Diseases

Journal of Cellular and Molecular Medicine, Volume 29, Issue 21, November 2025.
ABSTRACT Photoacoustic imaging (PAI) is an emerging imaging modality that provides high‐resolution, spatiotemporal insights into anatomical structures, functional parameters and molecular characteristics of tissues. By leveraging both endogenous absorbers, such as lipids and collagen, and exogenous contrast agents like nanoparticles and molecular dyes,
Kayleigh van Dijk, Margreet R. de Vries
wiley   +1 more source

Detection of intramyocardially injected DiR-labeled mesenchymal stem cells by optical and optoacoustic tomography

Photoacoustics, 2017
The distribution of intramyocardially injected rabbit MSCs, labeled with the near-infrared dye 1,1′-dioctadecyl-3,3,3′,3′-tetramethylindotricarbo-cyanine-iodide (DiR) using hybrid Fluorescence Molecular Tomography-X-ray Computed Tomography (FMT-XCT) and ...
Markus T. Berninger, Pouyan Mohajerani, Moritz Wildgruber, Nicolas Beziere, Melanie A. Kimm, Xiaopeng Ma, Bernhard Haller, Megan J. Fleming, Stephan Vogt, Martina Anton, Andreas B. Imhoff, Vasilis Ntziachristos, Reinhard Meier, Tobias D. Henning   +13 more
doaj   +1 more source

Non‐invasive characterization of melanoma depth at single‐cell resolution

Journal of the European Academy of Dermatology and Venereology, Volume 39, Issue 11, Page 1945-1954, November 2025.
Non‐invasive determination of Breslow depth would be beneficial for the clinical management of melanoma. We demonstrate that RSOM can achieve non‐invasive imaging of single melanocytes up to several millimetres in tissue. A pilot clinical study showed a high degree of correlation between RSOM and the standard for Breslow depth determination.
Juan Aguirre, Christine Gasteiger, Benedikt Hindelang, Markus Seeger, Andrei Bereznhoi, Ina Weidenfeld, Ulf Darsow, Andre C. Stiel, Susanne Annette Steimle‐Grauer, Christian Posch, Tilo Biedermann, Vasilis Ntziachristos   +11 more
wiley   +1 more source

Boron Difluoride Formazanate Dye With Donor Planarization Engineering for 1060 nm Laser Activated Photothermal Theranostics

Advanced Science, Volume 12, Issue 37, October 6, 2025.
The donor engineering strategy enhances the planarity of the π‐conjugated molecular framework, thereby promoting stronger intramolecular charge transfer (ICT). This structural refinement in FBDFDPA leads to a pronounced bathochromic shift in absorption from the NIR‐I to the NIR‐II region, enabling effective photothermal therapy (PTT) for tumors within ...
Kang Xu, Mengchen Luo, Weili Wang, Tian Zhang, Yang Chen, Jinjun Shao, Peng Chen, Xiaochen Dong, Yu Cai   +8 more
wiley   +1 more source

Reduced Muscle Force in Dystrophic DMDΔ52 Pigs Is Incompletely Restored by Systemic Transcript Reframing (DMDΔ51–52)

Journal of Cachexia, Sarcopenia and Muscle, Volume 16, Issue 5, October 2025.
ABSTRACT Background Duchenne muscular dystrophy (DMD) is a fatal X‐linked disease caused by mutations in the DMD gene, leading to dystrophin deficiency and progressive degeneration of skeletal and cardiac muscles. Pigs lacking DMD exon 52 (DMDΔ52) are a clinically severe model for DMD, mimicking molecular, functional and pathological hallmarks of the ...
Michaela Blasi, Hristiyan Hristov, Jan B. Stöckl, Martin Kraetzl, Sonja Fiedler, Elisabeth Kemter, Mayuko Kurome, Barbara Kessler, Josep M. Cambra, Valeri Zakhartchenko, Maggie C. Walter, Christian Kupatt, Nikolai Klymiuk, Thomas Fröhlich, Andreas Blutke, Michael Stirm, Florian Jaudas, Eckhard Wolf   +17 more
wiley   +1 more source

Optoacoustic Imaging and Tomography: Reconstruction Approaches and Outstanding Challenges in Image Performance and Quantification

Sensors, 2013
This paper comprehensively reviews the emerging topic of optoacoustic imaging from the image reconstruction and quantification perspective. Optoacoustic imaging combines highly attractive features, including rich contrast and high versatility in sensing ...
Daniel Razansky, Christian Lutzweiler
doaj   +1 more source

Multispectral optoacoustic tomography (MSOT) for imaging the particle size-dependent intratumoral distribution of polymeric micelles

International Journal of Nanomedicine, 2018
Zhaoqing Cong, Feifei Yang, Li Cao, Han Wen, Taotao Fu, Siqi Ma, Chunyu Liu, Lihui Quan, Yonghong Liao Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Institute of Medicinal Plant Development, Chinese Academy
Cong ZQ, Yang FF, Cao L, Wen H, Fu TT, Ma SQ, Liu CY, Quan LH, Liao YH   +8 more
doaj