Results 91 to 100 of about 2,572 (182)

Enhancing eMSOT with nonlinear mixed model approaches for precise blood oxygenation imaging in tissues

APL Photonics
Multispectral optoacoustic tomography (MSOT) utilizes multiple wavelengths to illuminate tissue, producing a series of optoacoustic images rich in spectral information.
Pengwei Han, Yiping Lv, Binxue Zhang, Shuang Wu, Jiayue Wang, Hao Zhang, Feng Gao, Jiao Li   +7 more
doaj   +1 more source

Multispectral Optoacoustic Tomography of Benign and Malignant Thyroid Disorders: A Pilot Study. [PDF]

J Nucl Med, 2019
This study aimed at evaluating hybrid multispectral optoacoustic tomography/ultrasound for imaging of thyroid disorders, including Graves' disease and thyroid nodules. Methods: The functional biomarkers and tissue parameters deoxygenated hemoglobin, oxygenated hemoglobin, total hemoglobin, saturation of hemoglobin, fat content, and water content were ...
Roll W, Markwardt NA, Masthoff M, Helfen A, Claussen J, Eisenblätter M, Hasenbach A, Hermann S, Karlas A, Wildgruber M, Ntziachristos V, Schäfers M.   +11 more
europepmc   +5 more sources

Thermosensitive Biodegradable Copper Sulfide Nanoparticles for Real-Time Multispectral Optoacoustic Tomography. [PDF]

ACS Appl Bio Mater, 2019
Although multifunctional inorganic nanoparticles have been extensively explored for effective cancer diagnosis and therapy, their clinical translation has been greatly impeded because of significant uptake in the reticuloendothelial system and concerns about potential toxicity.
Shi S, Wen X, Li T, Wen X, Cao Q, Liu X, Liu Y, Pagel MD, Li C.   +8 more
europepmc   +4 more sources

Multiview Hilbert transformation in full-ring transducer array-based photoacoustic computed tomography [PDF]

, 2017
Based on the photoacoustic (PA) effect, PA tomography directly measures specific optical absorption, i.e., absorbed optical energy per unit volume. We recently developed a full-ring ultrasonic transducer array-based photoacoustic computed tomography ...
Li, Lei, Shen, Yuecheng, Wang, Lihong V., Zhu, Liren   +3 more
core   +1 more source

Real‐Time Monitoring of Atherosclerotic Plaque Using β‐Galactosidase‐Activated Photoacoustic Tomography

Small, Volume 21, Issue 44, November 6, 2025.
Detecting Vascular Senescence: Novel Enzyme‐Responsive Photoacoustic Nanoprobes for Atherosclerotic Plaque Imaging. A lipid nanoprobe is developed that detects senescence‐associated β‐galactosidase in plaques via enzyme‐triggered spectral shifts. This platform enables dynamic tracking of atherosclerotic progression, 3D visualization on the extent and ...
Yifan Zhou, Hang Yang, Handi Deng, Feng Zhang, Junjie Jiang, Sibo Yang, Xiaodi Sun, Jiehong Wu, Yanan Li, Huijuan Jin, Hao Wang, Cheng Ma, Li‐Li Li, Bo Hu   +13 more
wiley   +1 more source

Breaking (Light) Barriers: Photoacoustics in Atherosclerotic Diseases

Journal of Cellular and Molecular Medicine, Volume 29, Issue 21, November 2025.
ABSTRACT Photoacoustic imaging (PAI) is an emerging imaging modality that provides high‐resolution, spatiotemporal insights into anatomical structures, functional parameters and molecular characteristics of tissues. By leveraging both endogenous absorbers, such as lipids and collagen, and exogenous contrast agents like nanoparticles and molecular dyes,
Kayleigh van Dijk, Margreet R. de Vries
wiley   +1 more source

Detection of intramyocardially injected DiR-labeled mesenchymal stem cells by optical and optoacoustic tomography

Photoacoustics, 2017
The distribution of intramyocardially injected rabbit MSCs, labeled with the near-infrared dye 1,1′-dioctadecyl-3,3,3′,3′-tetramethylindotricarbo-cyanine-iodide (DiR) using hybrid Fluorescence Molecular Tomography-X-ray Computed Tomography (FMT-XCT) and ...
Markus T. Berninger, Pouyan Mohajerani, Moritz Wildgruber, Nicolas Beziere, Melanie A. Kimm, Xiaopeng Ma, Bernhard Haller, Megan J. Fleming, Stephan Vogt, Martina Anton, Andreas B. Imhoff, Vasilis Ntziachristos, Reinhard Meier, Tobias D. Henning   +13 more
doaj   +1 more source

A practical guide to photoacoustic tomography in the life sciences [PDF]

, 2016
The life sciences can benefit greatly from imaging technologies that connect microscopic discoveries with macroscopic observations. One technology uniquely positioned to provide such benefits is photoacoustic tomography (PAT), a sensitive modality for ...
A Danielli, A De la Zerda, A de la Zerda, A Krumholz, A Ray, A Taruttis, A Taruttis, AG Bell, AP Jathoul, AS Goy, B Cox, BE Treeby, C Zhang, CGA Hoelen, D Razansky, DA Nedosekin, DK Yao, E Herzog, E Zhang, EI Galanzha, EI Galanzha, EM Strohm, EM Strohm, EM Strohm, G He, GP Luke, GS Filonov, H Li, HF Zhang, HP Brecht, HW Wang, J Jo, J Kim, J Laufer, J Laufer, J Laufer, J Levi, J Levi, J Staley, J Weber, J Xia, J Yao, J Yao, J Yao, J Yao, J Yao, J Yao, JB Tang, JJ Yao, JJ Yao, JM Yang, Junjie Yao, JW Kim, JY Kim, JY Liang, K Daoudi, K Jansen, KE Wilson, L Brannon-Peppas, L Vionnet, L Wang, LD Liao, LD Wang, LD Wang, Lihong V Wang, LV Wang, LV Wang, M Jeon, M Lamont, M Nasiriavanaki, M-L Li, MC Pilatou, MH Xu, NC Burton, NC Deliolanis, P Burgholzer, Q Shao, R Horstmeyer, R Nuster, RA Kruger, RA Kruger, RA Kruger, RA Kruger, S Mallidi, S Tzoumas, S Zackrisson, S-Y Lee, T Mitcham, TJ Allen, TN Erpelding, V Tsytsarev, VV Yakovlev, W Bost, W Song, WJ Akers, XD Wang, XL Deán-Ben, XS Bai, Y Cho, Z Xu, ZL Deng   +100 more
core   +2 more sources

Non‐invasive characterization of melanoma depth at single‐cell resolution

Journal of the European Academy of Dermatology and Venereology, Volume 39, Issue 11, Page 1945-1954, November 2025.
Non‐invasive determination of Breslow depth would be beneficial for the clinical management of melanoma. We demonstrate that RSOM can achieve non‐invasive imaging of single melanocytes up to several millimetres in tissue. A pilot clinical study showed a high degree of correlation between RSOM and the standard for Breslow depth determination.
Juan Aguirre, Christine Gasteiger, Benedikt Hindelang, Markus Seeger, Andrei Bereznhoi, Ina Weidenfeld, Ulf Darsow, Andre C. Stiel, Susanne Annette Steimle‐Grauer, Christian Posch, Tilo Biedermann, Vasilis Ntziachristos   +11 more
wiley   +1 more source

Seeing Through the Surface: Non-invasive Characterization of Biomaterial-Tissue Interactions Using Photoacoustic Microscopy [PDF]

, 2016
At the intersection of life sciences, materials science, engineering, and medicine, regenerative medicine stands out as a rapidly progressing field that aims at retaining, restoring, or augmenting tissue/organ functions to promote the human welfare ...
Wang, Lihong V., Xia, Younan, Zhang, Yu Shrike   +2 more
core   +1 more source