Results 61 to 70 of about 1,309 (169)

Combining radiotherapy with CAR‐T cell therapy for solid tumors: Challenges, mechanisms, and future directions

open access: yesPrecision Radiation Oncology, EarlyView.
Radiotherapy enhances CAR‐Tcell therapy by increasing antigenicity, improving trafficking, and reshaping the tumor microenvironment. Despite its dual effects, including potential immune suppression, understanding these mechanisms enables the development of strategies to maximize synergy in solid tumors.
Leran Qiu   +4 more
wiley   +1 more source

Multi-Target Tracking Algorithm Combined with High-Precision Map

open access: yesSensors, 2022
On high-speed roads, there are certain blind areas within the radar coverage, especially when the blind zone is in curved road sections; because the radar does not have the measurement point information in multiple frames, it is easy to have a large ...
Qingru An   +4 more
doaj   +1 more source

Nanobodies as next‐generation targeting platforms: From discovery technologies to translational biomedicine

open access: yesVIEW, EarlyView.
Nanobodies, derived from the variable domains of camelid heavy‐chain‐only antibodies, have emerged as transformative biomedical tools due to their nanoscale size, exceptional stability, and unique capacity to recognize cryptic epitopes. This review provides a comprehensive overview of the field, outlining the structural and biochemical features of ...
Zhenrui Ye, Xianyang Li, Meixiao Zhan
wiley   +1 more source

Tracking 'bunching' multitarget correlations

open access: yes, 2015
© 2015 IEEE. In point process theory, permanental processes are used to model statistical populations whose members tend to be attracted to each other ('bunch').
Mahler, Ronald, Ronald Mahler
core   +1 more source

Ecology of reintroduced Rocky Mountain bighorn sheep in Dinosaur National Monument La Ecología de Borrego Cimarron de las Montañas Rocosas Reintroducido en el Monumento Nacional de Dinosaurio

open access: yesWildlife Monographs, EarlyView.
We synthesized GPS telemetry, genetic, and pathogen data to evaluate metapopulation processes in a reintroduced Rocky Mountain bighorn sheep (Ovis canadensis canadensis) population in Dinosaur National Monument. We estimated subpopulation‐specific abundances and found 4 small subpopulations with high genetic diversity, partial connectivity, and ...
Sarah L. Carroll   +8 more
wiley   +1 more source

MULTITARGET TRACKING MENGGUNAKAN MULTIPLE HYPOTHESIS TRACKING DENGAN CLUSTERING TIME WINDOW DATA RADAR

open access: yesJUTI: Jurnal Ilmiah Teknologi Informasi, 2015
Sistem radar dibagi menjadi dua jenis yaitu sistem radar sipil dan sistem radar militer. Kedua jenis sistem radar tersebut memiliki kesamaan yaitu telah digunakan untuk pemantauan lalu lintas udara.
Gigih P. Cahyono, Handayani Tjandrasa
doaj   +1 more source

Poisson multi‐Bernoulli mixture filters with coloured measurement noise

open access: yesIET Radar, Sonar & Navigation, 2022
To solve multitarget tracking (MTT) problems with coloured measurement noise, this study proposes a Poisson multi‐Bernoulli mixture filter with coloured measurement noise (PMBM‐CMN) and a robust PMBM‐CMN filter.
Wenjuan Li   +4 more
doaj   +1 more source

Computational modelling of the pro‐ and antiarrhythmic effects of atrial high rate‐dependent trafficking of small‐conductance calcium‐activated potassium channels

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Small‐conductance calcium‐activated potassium (SK) channels are important for atrial repolarization and can be targeted for atrial‐specific antiarrhythmic treatments. We developed a computational model with a calcium sensor to study the effects of increased pacing rate (5 Hz), which enhances SK‐channel gating and forward ...
Stefan Meier   +3 more
wiley   +1 more source

Retrodiction for Multitarget Tracking [PDF]

open access: yes, 2009
Multi-Target Tracking (MTT), where the number of targets as well as their states are time-varying, concerns with the estimation of both the number of targets and the individual states from noisy sensor measurements, whose origins are unknown.
Nadarajah, N.
core  

Drugst.One DREAM—Drug repurposing through expert annotation and modification

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 13, Page 3503-3516, July 2026.
Background and Purpose Complex diseases often lack an actionable understanding of their underlying causal biological mechanisms, which leads to treating symptoms rather than causes. Network and systems medicine define disease mechanisms through disease‐associated genes, their encoded proteins and their protein–protein interactions (PPIs), thus forming ...
Lisa M. Spindler   +8 more
wiley   +1 more source

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