Results 61 to 70 of about 602,867 (155)

Multi‐omics–driven precision medicine

iMeta, EarlyView.
Multi‐omics‐driven precision medicine (MODPM) provides a multiscale, continuously learnable framework that integrates genomics, epigenomics, transcriptomics, proteomics, metabolomics, microbiome profiles, and clinical data. Powered by artificial intelligence and foundation models, MODPM enables cross‐modal representation learning, contextual modeling ...
Huibo Li, Zhe Zhao, Yifan Zhang, Yao Ma, Gaofei Hu, Min Zeng, Zhanqun Yang, Zixuan Zhao, Xin Zhou, Wei Hu, Yuxuan Sun, Meng Su, Jun Li, Matthew Whiteman, Wei Fu, Chao Zhong, Lemin Zheng, Long Chen, Hairong Lv, Rongsheng Zhao, Yi Zhun Zhu   +20 more
wiley   +1 more source

Reversing brain aging: Targeting energy metabolism in endogenous neural stem cells

Interdisciplinary Medicine, EarlyView.
Mechanism of endogenous neural stem cells (eNSCs) energy metabolism disorder leading to brain aging and targeted eNSCs intervention strategies (By biorender). The disorder of energy metabolism of eNSCs can lead to their resting and aging, and eventually lead to brain aging.
Chong Chen, Jiayi Wang, Jimin Yu, Yiran Zhou, Lihai Liu, Jing Liu, Liang Wang   +6 more
wiley   +1 more source

Tracking sperm whales using passive acoustics and particle filters

, 2011
Passive acoustics provides a powerful tool for marine mammal research and mitigation of the risk posed by high energy anthropogenic acoustic activities through monitoring animal positions.
Hadley, Mark Lyndon, Hadley, M.
core   +1 more source

Tracking 'bunching' multitarget correlations

, 2015
© 2015 IEEE. In point process theory, permanental processes are used to model statistical populations whose members tend to be attracted to each other ('bunch').
Mahler, Ronald, Ronald Mahler
core   +2 more sources

Multi-Target Tracking Algorithm Combined with High-Precision Map

Sensors, 2022
On high-speed roads, there are certain blind areas within the radar coverage, especially when the blind zone is in curved road sections; because the radar does not have the measurement point information in multiple frames, it is easy to have a large ...
Qingru An, Yawen Cai, Juan Zhu, Sijia Wang, Fengxia Han   +4 more
doaj   +1 more source

Toxicity Differences Between Microplastics and Nanoplastics in Organs: From Molecular Mechanisms to Potential Therapeutic Strategies

Med Research, EarlyView.
This review systematically compares the size‐dependent toxicity of microplastics and nanoplastics in the intestine, liver, kidney, lung, and brain. Particle size determines bioavailability, barrier penetration, and injury mechanisms. Because of their small size and high surface reactivity, NPs readily cross the intestinal epithelium and blood–brain ...
Yixian Cheng, Junjie Chen, Rui Fu, Jiawei Zhang, Jianguang Jia, Wei Wang, Zheng Zhang, Peng Zhang, Haosong Chen, Huake Cao, Gang Li, Weiwei Sheng, Ting Li, Bo Chen, Guodong Cao   +14 more
wiley   +1 more source

Phytochemicals as Multitarget Therapeutics in Pancreatic Cancer: Mechanisms, Clinical Evidence, and Translational Challenges

Phytotherapy Research, EarlyView.
Pancreatic cancer, particularly pancreatic ductal adenocarcinoma, is aggressive and often diagnosed late, making treatment challenging. This review highlights the potential of phytochemicals, such as curcumin and quercetin, as multitarget agents that influence key carcinogenic pathways. These compounds exhibit anticancer effects by inhibiting processes
Md. Rezaul Islam, Abdur Rauf, F. M. Shourav, Hanan A. Ogaly, Abdullah S. M. Aljohani, Waleed Al Abdulmonem, Kamala Badalova, Marcello Iriti   +7 more
wiley   +1 more source

MULTITARGET TRACKING MENGGUNAKAN MULTIPLE HYPOTHESIS TRACKING DENGAN CLUSTERING TIME WINDOW DATA RADAR

JUTI: Jurnal Ilmiah Teknologi Informasi, 2015
Sistem radar dibagi menjadi dua jenis yaitu sistem radar sipil dan sistem radar militer. Kedua jenis sistem radar tersebut memiliki kesamaan yaitu telah digunakan untuk pemantauan lalu lintas udara.
Gigih P. Cahyono, Handayani Tjandrasa
doaj   +1 more source

Poisson multi‐Bernoulli mixture filters with coloured measurement noise

IET Radar, Sonar & Navigation, 2022
To solve multitarget tracking (MTT) problems with coloured measurement noise, this study proposes a Poisson multi‐Bernoulli mixture filter with coloured measurement noise (PMBM‐CMN) and a robust PMBM‐CMN filter.
Wenjuan Li, Xingyu Lu, Aihong Lu, Hong Gu, Weimin Su   +4 more
doaj   +1 more source

Carbon dots as a smart nanoplatform for the blood‐brain barrier penetration and ischemic stroke therapy

Responsive Materials, EarlyView.
This review presents the structure and transport routes of the blood‐brain barrier, summarizes the ischemic stroke pathophysiological cascade, and discusses the BBB‐crossing mechanisms and multitarget therapeutic effects of carbon dots, demonstrating their promising theranostic potential for ischemic stroke.
Yanhan Huang, Xuan Hou, Haiping Zhao, Qi Kong, Xiayan Wang, Xiaokun Geng, Zaicheng Sun   +6 more
wiley   +1 more source