Results 41 to 50 of about 1,068,731 (282)
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
A demofobia na democracia moderna
Dans cet article, on cherche à montrer l'existence de principes de démophobie dans la théorie de la démocratie moderne. On observe que des propositions théoriques libérales ont tranché sur le fait de subsumer le demos dans le gouvernement de tous, la ...
Thais Florencio de Aguiar
doaj +1 more source
Agency Fact Sheet, Department of Iowa Workforce Development, FY2007 [PDF]
This document produced by the Iowa Department of Administrative Services has been developed to provide a multitude of information about executive branch agencies/department on a single sheet of paper.
core
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Teologi Lokal dalam Konteks Global
Today in the globalization process the poor is marginalized. This reflection is based on the Indonesian context of economic dependence and marginalization of the poor and the powerless.
Johanes Baptista Giyana Banawiratma
doaj +1 more source
Agency Fact Sheet, Department of Commerce: Utilities Board, FY2009 [PDF]
This document produced by the Iowa Department of Administrative Services has been developed to provide a multitude of information about executive branch agencies/department on a single sheet of paper.
core
The Multitude of Unresolved Continuum Sources at 1.6 microns in Hubble Space Telescope images of Seyfert Galaxies [PDF]
We examine 112 Seyfert galaxies observed by the Hubble Space Telescope (HST) at 1.6 microns. We find that ~50% of the Seyfert 2.0 galaxies which are part of the Revised Shapeley-Ames (RSA) Catalog or the CfA redshift sample contain unresolved continuum ...
A. Alonso‐Herrero +18 more
core +5 more sources
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Beyond the Public and the Private : Thomas Spence and the Current Debate on Common Property
The purpose of this article is to show the concept of common property of Thomas Spence (1750-1814) as a genealogy of the current political debate about the commons. This debate is characterized by two main ways of conceiving of common property : one that
Matilde Cazzola
doaj +1 more source

