Results 91 to 100 of about 13,574 (319)
Multivalent Ligands for Siglecs [PDF]
Siglecs have emerged as an important family of immunomodulatory glycan-binding proteins that can bind sialoside ligands both on the same cell surface, in cis, and on other cells, in trans. Expression of siglecs varies among a variety of immune cells, and tools to probe siglecs on these cells are crucial to understanding their function.
Mary K, O'Reilly, James C, Paulson
openaire +2 more sources
Terminal domains of recombinant collagen‐like silk regulate hierarchical self‐assembly across molecular and material scales. We show that terminal domains of collagen‐like silk enhance triple‐helix stability and drive liquid–liquid phase separation, enabling reversible formation of fibers and self‐healing films.
Mengjie Shen +5 more
wiley +1 more source
Short peptides in minimalistic biocatalyst design [PDF]
We review recent developments in the use of short peptides in the design of minimalistic biocatalysts focusing on ester hydrolysis. A number of designed peptide nanostructures are shown to have (modest) catalytic activity. Five features are discussed and
Duncan, Krystyna, Ulijn, Rein V.
core +2 more sources
Biocompatible but Antibacterial Mechanism of Graphene Oxide for Sustainable Antibiotics
Graphene oxide (GO) exhibits selective antibacterial activity through specific interactions between its oxygen functional groups and bacterial membrane phospholipid POPG, causing membrane destabilization while maintaining biocompatibility. Model membrane studies and infected wound models in mice and pigs demonstrate effective bacterial suppression and ...
Sujin Cha +15 more
wiley +1 more source
Bioprinting Organs—Science or Fiction?—A Review From Students to Students
Bioprinting artificial organs has the potential to revolutionize the medical field. This is a comprehensive review of the bioprinting workflow delving into the latest advancements in bioinks, materials and bioprinting techniques, exploring the critical stages of tissue maturation and functionality.
Nicoletta Murenu +18 more
wiley +1 more source
Conjugates of Porphyrins and Hyperbranched Polyglycerol for an Application in Photodynamic Therapy [PDF]
This thesis consists of four different parts of the synthesis and investigation of various porphyrins containing different types of linkers for the connection to substrates, conjugates of these porphyrins with hyperbranched polyglycerol (hPG) in ...
Staegemann, Michael Holger
core +1 more source
Antimicrobial peptide (AMP)‐loaded nanocarriers provide a multifunctional strategy to combat drug‐resistant Mycobacterium tuberculosis. By enhancing intracellular delivery, bypassing efflux pumps, and disrupting bacterial membranes, this platform restores phagolysosome fusion and macrophage function.
Christian S. Carnero Canales +11 more
wiley +1 more source
Carbohydrate inhibitors of cholera toxin
Cholera is a diarrheal disease caused by a protein toxin released by Vibrio cholera in the host’s intestine. The toxin enters intestinal epithelial cells after binding to specific carbohydrates on the cell surface.
Vajinder Kumar, W. Bruce Turnbull
doaj +1 more source
Harmonized tuning of nucleic acid and lectin binding properties with multivalent cyclodextrins for macrophage-selective gene delivery [PDF]
Polycationic amphiphilic cyclodextrins (paCDs) have been shown to behave as efficient non-viral gene carriers paralleling the efficacy of commercial vectors towards a variety of cell lines.
Benito, Juan M. +6 more
core +1 more source
Multivalency, autoinhibition, and protein disorder in the regulation of interactions of dynein intermediate chain with dynactin and the nuclear distribution protein [PDF]
Kayla A. Jara +7 more
openalex +2 more sources

