Results 21 to 30 of about 1,484 (137)

Engineering Antibodies into Targeted Chimeras: From Recognition Modules to Programmable Degraders

Advanced Science, EarlyView.
Antibody can be engineered into diverse lysosome‐targeting chimeras that convert target recognition into active degradation. By coupling antibody binding with recruited receptors, encoded domains, conjugated ligands, or nanoparticle scaffolds, these antibody‐associated targeted chimeras (AbTACs) platforms direct extracellular and membrane proteins ...
Kaige Chen, Quanyin Hu
wiley   +1 more source

Emerging Materials and Future Strategies for Solid Oxide Electrochemical Cells

Advanced Energy Materials, EarlyView.
Solid oxide electrochemical cells operate under strongly coupled electrochemical and thermodynamic conditions, where performance is constrained by interactions among crystal structure, defect chemistry, and interfacial evolution. This review, based on a structure‐defect‐property‐durability framework, reveals the roles of lattice symmetry and defect ...
Qiuchun Lu, Yufei Zhang, Han Zhao, Pooi See Lee, Daniel H.C. Chua   +4 more
wiley   +1 more source

Deciphering Intricacies in Directional CO2 Conversion From Electrolysis to CO2 Batteries

Advanced Energy Materials, EarlyView.
This review will delve into the inherent connections and distinctions of CO2‐directed conversion in ECO2RR and CO2 batteries, in terms of product types, catalyst selection, catalytic mechanisms, and electrochemical performances, while proposing a benchmarking framework for the evaluation of CO2 batteries and innovative CO2 battery configurations for ...
Changfan Xu, Huaping Zhao, Lizhuang Chen, Weidong Shi, Guosheng Shao, Yong Lei   +5 more
wiley   +1 more source

Colour Choice as a Strategic Instrument in Neuromarketing

Mathematics
Social relationships have been and are the basis for achieving objectives of all kinds, whether altruistic or lucrative. Among the aspects that make up non-verbal communication are physical appearance in general, clothing, and, in particular, colour ...
Andréia C. Müller, Jaime Gil-Lafuente, Joan Carles Ferrer-Comalat   +2 more
doaj   +1 more source

Molecular Logic of DNMT3A1 Recruitment: Resolving Multivalency at the Chromatin Interface

Abstract Histone modifications correlate with DNA methylation, but the underlying mechanisms remain unclear. The DNA methyltransferase DNMT3A1 engages nucleosomes through multivalent interactions with linker DNA, histone H3 tails, the acidic patch, and ubiquitinated H2A.
Drew McDonald, Emma Sachs, Talia Rapoport, Daniel Niizawa, Manxin Cao, Nataly Konechne, Elizabeth Lee, Norbert Reich   +7 more
openaire   +1 more source

The Jekyll and Hyde Nature of Tetrazoles in Polymer Science: From Intrinsic Electronic Duality to Programmable Macromolecular Function

Angewandte Chemie International Edition, EarlyView.
Tetrazoles are reframed as substitution‐programmable heterocycles rather than static functional groups in polymer chemistry. By linking electronic identity to synthetic strategy and polymer architecture, this mini‐review establishes a design framework for translating tetrazole duality into predictable macromolecular function.
Meryem S. Akdemir, Hatice Mutlu
wiley   +1 more source

BODIPY‐based J‐aggregates: From supramolecular chemistry to NIR bioimaging and phototherapies

Bulletin of the Korean Chemical Society, EarlyView.
BODIPY dyes form ordered J‐aggregates through controlled supramolecular self‐assembly, producing narrow, red‐shifted absorption bands with small Stokes shifts. This review highlights design strategies governing J‐aggregation, structure–property relationships, and applications in sensing, bioimaging, and phototherapy, guiding functional BODIPY‐based ...
Pooja Sharma, Yeonkyeong Lee, Youngmi Kim   +2 more
wiley   +1 more source

Cryo-EM structures of higher order Gephyrin oligomers reveal principles of inhibitory postsynaptic scaffold organization

Nature Communications
Gephyrin, the principal scaffolding protein of inhibitory postsynaptic densities, clusters glycine and GABAA receptors via multivalent interactions. It features structured N and C terminal domains connected by an intrinsically disordered linker. Although
Diego Ortiz-López, Tamsanqa T. Hove, Christiane Huhn, Serena Camuso, Pia M. van gen Hassend, Bodo Sander, Benjamin F. N. Campbell, Shiva K. Tyagarajan, Andreas Plückthun, Christian G. Specht, Hans M. Maric, Bettina Böttcher, Hermann Schindelin   +12 more
doaj   +1 more source

Infinite Functional Versatility, Formidable Limits: Evaluating Gallium‐Based Liquid Metals in Rechargeable Batteries

Carbon Energy, EarlyView.
Beyond the hype surrounding the self‐healing properties of gallium‐based liquid metals (Ga‐LMs), this perspective critically examines their functional roles in metal‐ion batteries, highlighting both their underlying merits and the often‐overlooked challenges, including non‐representative design and testing configurations, performance overestimations ...
Turly P. P. Sumanasekara, Petar Jovanović, Ali Zavabeti, Dan Yang, Mainak Majumder, Anthony F. Hollenkamp, Torben Daeneke, Mahdokht Shaibani   +7 more
wiley   +1 more source

Precision Chemistry for Protein Lysine Modification

Chemistry – A European Journal, EarlyView.
Selective modification of lysine residues is challenging due to their similar intrinsic reactivity. Inspired by enzymatic recognition, ligand‐guided electrophiles enable site‐selective labeling and functionalization, while ligand‐guided catalyses achieve regioselective installation of bio‐relevant post‐translational modifications.
Mayu Onoda, Motomu Kanai
wiley   +1 more source