Results 41 to 50 of about 1,484 (137)

Artificial intelligence empowers targeted protein degradation: Core technological innovations, multi‐scenario applications, and translational prospects

Smart Molecules, EarlyView.
AI is transforming TPD by improving the design, prediction, and optimization of degraders such as PROTACs, molecular glues, and LYTACs. This review summarizes key AI‐driven advances, highlights applications across drug discovery stages, and discusses remaining challenges and future directions for accelerating the development of therapies against ...
Shuanglin Qin, Rui Peng, Guangshuai Zhang, Si Yan, Jin Xiao, Zishu Liu, Ziyu Tan, Qingqing Xie, Shangjie Li, Wei Luo, Xiaohe Xiao   +10 more
wiley   +1 more source

Recent Advances in Photocatalyst‐Driven Protein Labeling and Proximity Mapping

The Chemical Record, EarlyView.
Photocatalyst‐driven protein labeling and proximity mapping have rapidly advanced as powerful strategies for spatiotemporal control in complex biological environments. This review integrates recent developments across single‐electron transfer and energy transfer‐based mechanisms and highlights how catalyst design, reactive intermediates, and diffusion ...
Shinichi Sato, Kazuki Miura, Juki Nakao, Hiroyuki Nakamura   +3 more
wiley   +1 more source

Diagnostic antibodies at an inflection point: From discovery platforms to design‐oriented engineering

VIEW, EarlyView.
This study systematically organizes the evolution of diagnostic antibodies from discovery platforms to design‐oriented engineering and analyzes the strengths and limitations of each approach. Meanwhile, it provides a critical, literature‐driven synthesis of current challenges, proposing integrated strategies for assay‐aware and function‐driven antibody
Qitao Song, Lulai Xu, Weilin Wu, Fei Xie, Yantong Pan, Tiantian Yang, Xiaoxia Xu, Yanyin Lin, Lihua Zhang, Jiahui Zhou, Junyou Zhou, Linping Li, Zhanhui Wang, Weijing Yi, Jing Wang   +14 more
wiley   +1 more source

‘Everything is a signal’: speaking circuits and noisy signs in the making of language‐oriented AI « Tout est signal » : circuits parlants et signes bruyants dans la création de l'IA orientée langage

Journal of the Royal Anthropological Institute, EarlyView.
Contemporary artificial intelligence (AI) technologies are often presumed to be capable of revealing unmediated truths about the world, including the truths language might hold, echoing the long‐standing assertion that language's primary function is to directly translate reality.
Beth M. Semel
wiley   +1 more source

THE URBANOLOGISTS COME TO TOWN: Professional Life and Work in the Urban Solutions Industry

International Journal of Urban and Regional Research, EarlyView.
Abstract This article charts the upsurge of an eclectic global community of professionals new to the field of urban policy and governance, animated by playful and celebratory attitudes towards cities and urbanization: the urbanologists. It contributes to debates in critical urban theory and critical ethnographies of technology to problematize ...
Rachel Bok
wiley   +1 more source

Privileged Precarity: How the Mobile Middle Class Leverage Housing Insecurity as Labour Market Strategy

The British Journal of Sociology, EarlyView.
ABSTRACT How does the ability to weather insecurity give some an upper‐hand over others? This paper examines the interrelationship between housing and labour market precarity among middle class young professionals. Drawing on interviews with residents of co‐living schemes—for‐profit shared housing where tenants are on temporary rental contracts—it ...
Tim White
wiley   +1 more source

Religio‐Racial Lines, Intimate Ties: Christian–Muslim Couples, Birth Rituals, and the Bounds of Belonging

Journal for the Scientific Study of Religion, EarlyView.
ABSTRACT Building on scholarship that conceptualizes race and religion as co‐constitutive forces within a “race‐religion constellation,” this article explores how this entanglement—profoundly infused and structured by secularity—is lived and negotiated in everyday life.
Deniz Aktaş
wiley   +1 more source

Intelligent design of artificial biocatalyst for biomedical diseases

Journal of Intelligent Medicine, Volume 3, Issue 3, Page 220-249, September 2026.
This review summarizes recent advances in the intelligent design of artificial biocatalysts for biomedical diseases. By leveraging tailored design strategies, including environment‐responsive engineering and rational/artificial intelligence‐aided optimization, these biocatalysts enable precise modulation of pathological microenvironments and targeted ...
Lijie Zhang, Nan Song, Huanhuan Qiao, Si Sun   +3 more
wiley   +1 more source

Human Capital 4.0: Readiness of Initial Vocational Education Programmes in Italy and Germany

International Journal of Training and Development, Volume 30, Issue 3, Page 320-333, September 2026.
ABSTRACT The rapid pace of technological innovation and the advent of Industry 4.0 have profoundly transformed labour markets and the nature of work. This paper examines the preparedness of Initial Vocational Education and Training (IVET) programmes in Germany and Italy to meet the demands of Human Capital 4.0. Utilising a comparative analysis of three
Luca Antonazzo, Susanne Peters
wiley   +1 more source

National Relics: Secular Sacrality, Museums, and Heritage‐Making in Nineteenth‐Century Chile

Museum Anthropology, Volume 49, Issue 2, Fall 2026.
ABSTRACT This article examines how objects and bodily remains are transformed and ritualized into national relics through collecting and exhibiting practices in museums. Focusing on nineteenth‐century Chile, it draws on archival sources, material culture theory, and the anthropology of religion to argue that objects associated with Chile's nation‐state
Hugo Rueda Ramírez
wiley   +1 more source