Results 41 to 50 of about 1,574 (155)
Dual stimuli-responsive self-assembled supramolecular nanoparticles [PDF]
, 2014 Supramolecular nanoparticles (SNPs) encompass multiple copies of different building blocks brought together by specific noncovalent interactions. The inherently multivalent nature of these systems allows control of their size as well as their assembly ...
Stoffelen, C. +3 more
core +1 more source
Intelligent design of artificial biocatalyst for biomedical diseases
Journal of Intelligent Medicine, EarlyView.This review summarizes recent advances in the intelligent design of artificial biocatalysts for biomedical diseases. By leveraging tailored design strategies, including environment‐responsive engineering and rational/artificial intelligence‐aided optimization, these biocatalysts enable precise modulation of pathological microenvironments and targeted ...
Lijie Zhang +3 more
wiley +1 more source
Nature CommunicationsGephyrin, the principal scaffolding protein of inhibitory postsynaptic densities, clusters glycine and GABAA receptors via multivalent interactions. It features structured N and C terminal domains connected by an intrinsically disordered linker. Although
Diego Ortiz-López +12 more
doaj +1 more source
Applying concepts of fuzzy cognitive mapping to model IT/IS investment evaluation factors [PDF]
, 2002 The justification process is a major concern for many organisations that are considering the adoption of Information Technology (IT) and Information Systems (IS), and is a barrier to its implementation.
Sharif, AM +3 more
core
Peptide‐based responsive molecular fluorescent probes for precision oncology
Responsive Materials, EarlyView.Peptide‐based responsive fluorescent probes have emerged as adaptive functional materials for precision tumor theranostics, combining tumor‐selective recognition, programmable stimulus responsiveness, and modular tunability. They enable high‐contrast imaging, intraoperative guidance, real‐time monitoring, and multimodal applications, while next ...
Xing Wang +6 more
wiley +1 more source
Existence Assumptions and Logical Principles: Choice Operators in Intuitionistic Logic [PDF]
, 2015 Hilbert’s choice operators τ and ε, when added to intuitionistic logic, strengthen it. In the presence of certain extensionality axioms they produce classical logic, while in the presence of weaker decidability conditions for terms they produce various ...
Mulvihill, Corey Edward
core
Recent Advances in Photocatalyst‐Driven Protein Labeling and Proximity Mapping
The Chemical Record, EarlyView.Photocatalyst‐driven protein labeling and proximity mapping have rapidly advanced as powerful strategies for spatiotemporal control in complex biological environments. This review integrates recent developments across single‐electron transfer and energy transfer‐based mechanisms and highlights how catalyst design, reactive intermediates, and diffusion ...
Shinichi Sato +3 more
wiley +1 more source
VIEW, EarlyView.This study systematically organizes the evolution of diagnostic antibodies from discovery platforms to design‐oriented engineering and analyzes the strengths and limitations of each approach. Meanwhile, it provides a critical, literature‐driven synthesis of current challenges, proposing integrated strategies for assay‐aware and function‐driven antibody
Qitao Song +14 more
wiley +1 more source
Journal of Analytical Science and TechnologyUrinary tract infections involving methicillin-resistant Staphylococcus aureus (MRSA) pose significant clinical challenges, necessitating timely diagnosis and appropriate therapeutic intervention.
Shaojiang Li +3 more
doaj +1 more source