Results 231 to 240 of about 739,378 (304)

Socioeconomic Determinants of Diabetes Self-Care and Health Literacy Among Adults in Southern Riyadh. [PDF]

Healthcare (Basel)
Almutairi M, Alshehri WM, Alodhailah AM, Almutairy BM.   +3 more
europepmc   +1 more source

A Blood‐Derived Factor Rescues ALS: Platelet Factor 4 Activates OPTN‐Dependent Autophagy to Clear SOD1 Aggregates Independently of PINK1

Advanced Science, EarlyView.
Systemic platelet factor 4 (PF4) is significantly depleted in amyotrophic lateral sclerosis (ALS). Peripheral PF4 replenishment restores central proteostasis by driving OPTN‐dependent, PINK1‐independent selective autophagy in motor neurons. This intervention effectively clears toxic SOD1 aggregates, blunts glial activation, and preserves neuromuscular ...
Qingjian Xie, Yanbo Zhu, Wenhua Jiang, Haobo Xie, Yaojia Li, Mengjie Hu, Kezheng Li, Huan Yu, Yixuan Pan, Chaoyi Jiang, Xueqin Song, Dongsheng Fan, Binbin Deng   +12 more
wiley   +1 more source

Development and external validation of a nomogram for overall survival in oral tongue squamous cell carcinoma using machine learning-assisted feature selection. [PDF]

Sci Rep
Zhang Y, Liao Y, Su Z, Song L, Ma Z, Liu H, Li J, Jiang L.   +7 more
europepmc   +1 more source

Review of Gastrointestinal Capsule Robots: Materials, Actuation, Diagnostics, and Therapeutics

Advanced Science, EarlyView.
This review examines gastrointestinal capsule robots through a systems engineering lens, covering shell materials, actuation and localization strategies, diagnostic modalities, therapeutic interventions, and commercialization status. By mapping the complete technological chain from fabrication to clinical deployment, this work identifies critical gaps ...
Zengsheng Li, Zhongguo Ren, Yiliang Lin, Xianfeng Xia, Tianlong Li, Kai Fung Chan, Philip Wai Yan Chiu, Wei Peng Yong, Mengmeng Sun   +8 more
wiley   +1 more source

Predicting Pregnancy After Fixed-Time Artificial Insemination in Goats: Comparative Performance of Multivariable Logistic Regression and Random Forest Models. [PDF]

Animals (Basel)
Rodríguez-Vargas A, Rivas-Flores J, Ruiz-Chamorro J, Galván-Cavero G, Mendoza-Ordoñez G, Ortiz-Morera N, Cruz-Luis J.   +6 more
europepmc   +1 more source

Data‐Driven Design of Self‐Adhesive Epidermal Electrodes and Sensors

Advanced Science, EarlyView.
This work presents self‐adhesive, stretchable epidermal electrodes and sensors developed through a data‐driven design framework that integrates artificial neural networks with genetic algorithms. By tailoring optimization objectives, either maximizing electrical conductivity and adhesion or enhancing piezoresistive sensitivity, the study enables the ...
Xuan Li, Shilei Wang, Milad Razbin, Danish Tahir, Chen Sang, Shuhua Peng, Markus Müllner, Wenlong Cheng, Wei Chen, Chun Hui Wang, Shuying Wu   +10 more
wiley   +1 more source

Multi-parametric quantitative MRI for characterizing of lumbar intervertebral disc high-intensity zones in patients with chronic low back pain. [PDF]

J Orthop Surg Res
Meng L, Liu X, Jiang K, Huang L, Ma G, Sheng M, Zhao W, Zhong H.   +7 more
europepmc   +1 more source

Systematic Multi‐Level Analyses Decode the Arthritis‐Neurodegeneration Axis With In Vivo Validation

Advanced Science, EarlyView.
Arthritis and neurodegeneration are usually studied as separate disorders, but this study connects them through population evidence, genetic inference, transcriptomic mapping, and mouse models. It highlights RNF40 as a context‐dependent joint‐brain candidate, induced in inflammatory joints yet functionally linked to dopamine‐neuron vulnerability ...
Jinwen Wang, Wenhui Xie, Lei Yang, Zhengrong Wang, Yi Huang, Peng Huang, Yuan Liu, Jun Hu   +7 more
wiley   +1 more source

Predictors of Exclusive Breastfeeding Amongst Mothers Living With HIV in Sub-Saharan Africa: A Scoping Review. [PDF]

Health Sci Rep
Ives L, Ji X, Kupolati MD, Khoza AM, Tshiambara P.   +4 more
europepmc   +1 more source