Results 31 to 40 of about 2,440,721 (342)

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Optimization of multivariate analysis for IACT stereoscopic systems

open access: yes, 2010
Multivariate methods have been recently introduced and successfully applied for the discrimination of signal from background in the selection of genuine very-high energy gamma-ray events with the H.E.S.S. Imaging Atmospheric Cerenkov Telescope.
Dubois, F.   +4 more
core   +3 more sources

Tumor mutational burden as a determinant of metastatic dissemination patterns

open access: yesMolecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal   +4 more
wiley   +1 more source

Multivariate analysis of soybean genotypes

open access: yesJournal of Agriculture and Natural Resources, 2020
The experiments were conducted using randomized complete block design with three replications at the research field of Agriculture Botany Division, Khumaltar, Lalitpur, Nepal in 2016 and 2017 to evaluate sixteen soybean genotypes using multivariate ...
Pallavi Kumari Singh   +2 more
doaj   +1 more source

Permutation inference methods for multivariate meta-analysis

open access: yes, 2019
Multivariate meta-analysis is gaining prominence in evidence synthesis research because it enables simultaneous synthesis of multiple correlated outcome data, and random-effects models have generally been used for addressing between-studies ...
Furukawa, Toshi A.   +2 more
core   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

open access: yesMolecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta   +10 more
wiley   +1 more source

Multivariate Analysis Applications in X-ray Diffraction

open access: yesCrystals, 2020
Multivariate analysis (MA) is becoming a fundamental tool for processing in an efficient way the large amount of data collected in X-ray diffraction experiments. Multi-wedge data collections can increase the data quality in case of tiny protein crystals;
Pietro Guccione   +3 more
doaj   +1 more source

Multivariate analysis of the globular clusters in M87

open access: yes, 2015
An objective classification of 147 globular clusters in the inner region of the giant elliptical galaxy M87 is carried out with the help of two methods of multivariate analysis.
Chattopadhyay, Tanuka   +2 more
core   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Discriminant analysis of multivariate spatial regressions

open access: yesLietuvos Matematikos Rinkinys, 2001
There is not abstract.
Kęstutis Dučinskas, Jūratė Šaltytė
doaj   +3 more sources

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