Results 31 to 40 of about 23,268,891 (291)

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa   +7 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Multivariate analysis of soybean genotypes

open access: yesJournal of Agriculture and Natural Resources, 2020
The experiments were conducted using randomized complete block design with three replications at the research field of Agriculture Botany Division, Khumaltar, Lalitpur, Nepal in 2016 and 2017 to evaluate sixteen soybean genotypes using multivariate ...
Pallavi Kumari Singh   +2 more
doaj   +1 more source

COSIMA data analysis using multivariate techniques [PDF]

open access: yesGeoscientific Instrumentation, Methods and Data Systems, 2015
We describe how to use multivariate analysis of complex TOF-SIMS (time-of-flight secondary ion mass spectrometry) spectra by introducing the method of random projections.
J. Silén   +6 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Applied Multivariate Research, v.12 no.3 (complete version)

open access: yes, 2007
The third issue of Applied Multivariate Research edited by Dennis L. JacksonThe article "Cluster analysis and rankings of Canadian universities: Misadventures with rank-based data and implications for the welfare of students" by Kenneth M.

core   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

PC&CA - Tool for Polyphenols Content Monitoring at the End of Spring Depending on Organic and/or Mineral Fertilization of Perennial Grassland

open access: yesBulletin of University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca: Agriculture, 2018
The present research proposed to use Principal Components & Classification Analysis (PC&CA) as tool for the polyphenols content monitoring of perennial forages, at the end of May 2008, from a Romanian grassland fertilized since 2003.
Monica HARMANESCU
doaj   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

open access: yesMolecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen   +19 more
wiley   +1 more source

A quimiometria nos cursos de graduação em química: proposta do uso da análise multivariada na determinação de pkª

open access: yesQuímica Nova, 2014
An experiment was proposed applying the Chemometric approach of Multivariate Analysis for inclusion in undergraduate Chemistry courses to promote and expand the use of this analytical-statistical tool. The experiment entails the determination of the acid
Paulo Cesar de Souza Pereira   +9 more
doaj   +1 more source

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