Results 41 to 50 of about 1,306,676 (292)

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Multivariate analysis of soybean genotypes

Journal of Agriculture and Natural Resources, 2020
The experiments were conducted using randomized complete block design with three replications at the research field of Agriculture Botany Division, Khumaltar, Lalitpur, Nepal in 2016 and 2017 to evaluate sixteen soybean genotypes using multivariate ...
Pallavi Kumari Singh, Jiban Shrestha, Ujjawal Kumar Singh Kushwaha   +2 more
doaj   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

Proceedings of the Society Multivariate Experimental Psychology (SMEP), European Branch

, 1975
Proceedings editor introduction and abstracts of papers presented at the 6th conference of the European branch of the Society of Multivariate Experimental Psychology held in Germany on September 12-13, 1974.Research problems in multivariate experimental ...
Sarris, Viktor
core   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

PC&CA - Tool for Polyphenols Content Monitoring at the End of Spring Depending on Organic and/or Mineral Fertilization of Perennial Grassland

Bulletin of University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca: Agriculture, 2018
The present research proposed to use Principal Components & Classification Analysis (PC&CA) as tool for the polyphenols content monitoring of perennial forages, at the end of May 2008, from a Romanian grassland fertilized since 2003.
Monica HARMANESCU
doaj   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

FEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta, Nidhi Yadav, Subhasmita Das, R. Rajendra Kumar Reddy, Nupur Sharma, Amol Ratnakar Suryawanshi, Jaswinder Singh Maras, Ranjan Kumar Nanda   +7 more
wiley   +1 more source

A quimiometria nos cursos de graduação em química: proposta do uso da análise multivariada na determinação de pkª

Química Nova, 2014
An experiment was proposed applying the Chemometric approach of Multivariate Analysis for inclusion in undergraduate Chemistry courses to promote and expand the use of this analytical-statistical tool. The experiment entails the determination of the acid
Paulo Cesar de Souza Pereira, Camila Fabiano de Freitas, Cristiane Santi Chaves, Bianca Martins Estevão, Diogo Silva Pellosi, André Luiz Tessaro, Vagner Roberto Batistela, Ieda Spacino Scarminio, Wilker Caetano, Noboru Hioka   +9 more
doaj   +1 more source

Multivariate Analysis Applications in X-ray Diffraction

Crystals, 2020
Multivariate analysis (MA) is becoming a fundamental tool for processing in an efficient way the large amount of data collected in X-ray diffraction experiments. Multi-wedge data collections can increase the data quality in case of tiny protein crystals;
Pietro Guccione, Mattia Lopresti, Marco Milanesio, Rocco Caliandro   +3 more
doaj   +1 more source

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

FEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source