Ecologically‐Valid Emotion Signatures Enhance Mood Disorder Diagnostics
Advanced Science, EarlyView.This study identifies ecologically‐valid Divergent Emotional Functional Networks (DEFN), derived from dynamic functional connectivity during naturalistic movie watching. The DEFN reliably enhances diagnostic accuracy for mood disorders, including major depressive and bipolar disorders, demonstrating strong reproducibility across demographic factors and
Shuyue Xu +6 more
wiley +1 more source
Ecological Transition and Sustainable Development, A Multivariate Statistical Analysis to Guide the Policies of the National Recovery and Resilience Plan. [PDF]
Soc Indic Res, 2023 Perchinunno P +3 more
europepmc +1 more source
Advanced Science, EarlyView.PFOA exposure induces pregnancy loss by promoting glutaminolysis, which further causes ammonia accumulation in macrophages. Cellular ammonia retention results in damage to mitochondria and lysosomes, which leads to cell death eventually. Impaired lysosomes also decrease the secretion of the Cathepsin B (CTSB), and attenuate macrophage infiltration and ...
Yongbo Zhao +6 more
wiley +1 more source
Identification of late-life depression and mild cognitive impairment via serum surface-enhanced Raman spectroscopy and multivariate statistical analysis. [PDF]
Biomed Opt Express, 2023 Yan D +6 more
europepmc +1 more source
Advanced Science, EarlyView.PDAC has a poor prognosis due to chemoresistance. We revealed that MCU upregulation is associated with chemoresistance and stemness in PDAC. MCU‐mediated Ca2+ influx induced ER stress, activating the PERK‐ATF4/NRF2 axis to enhance PSAT1/SLC711 expression and glutathione synthesis, reducing ROS and maintaining stemness.
Zekun Li +17 more
wiley +1 more source
Evaluation of raw and processed Phellodendri Chinensis Cortex using the quality marker analysis strategy by UHPLC-Q-Orbitrap MS and multivariate statistical analysis. [PDF]
Front Chem, 2023 Wang W, Shi X, Zhu G.
europepmc +1 more source
Classification of the EU countries labour markets [PDF]
The objective of the paper is to classify the labour markets of the EU member states on the basis of selected employment and unemployment indicators. In order to achieve the study target, the adequate multivariate exploration procedures have been chosen.
Kaba, Bohumil
core +1 more source
Advanced Science, EarlyView.A predictive model for 3D printability is developed by integrating rheological analysis, including the Large Amplitude Oscillatory Shear (LAOS) test, with machine learning. With prediction errors under 10%, the model shows that post‐extrusion recovery controls horizontal printability, while high‐strain‐rate nozzle flow dictates vertical printability ...
Eun Hui Jeong +7 more
wiley +1 more source
Multivariate Statistical Analysis for the Detection of Air Pollution Episodes in Chemical Industry Parks. [PDF]
Int J Environ Res Public Health, 2022 Zhao X, Cheng K, Zhou W, Cao Y, Yang SH.
europepmc +1 more source
PD‐1 Inhibits CD4+ TRM‐Mediated cDC1 Mobilization via Suppressing JAML in Human NSCLC
Advanced Science, EarlyView.CD4+ tissue‐resident memory T cells (TRMs) in non‐small cell lung cancer recruit conventional type 1 dendritic cells via XCL1‐XCR1 signaling, orchestrating antitumor immunity. The costimulatory molecule JAML is essential for this process. PD‐1 blockade restores JAML expression and cDC1 mobilization, while JAML agonists synergize with anti‐PD‐1 therapy,
Zheyu Shao +16 more
wiley +1 more source