Repeated introductions and intensive community transmission fueled a mumps virus outbreak in Washington State. [PDF]
In 2016/2017, Washington State experienced a mumps outbreak despite high childhood vaccination rates, with cases more frequently detected among school-aged children and members of the Marshallese community.
Moncla LH+9 more
europepmc +3 more sources
Establishing a small animal model for evaluating protective immunity against mumps virus. [PDF]
Although mumps vaccines have been used for several decades, protective immune correlates have not been defined. Recently, mumps outbreaks have occurred in vaccinated populations.
Adrian Pickar+6 more
doaj +2 more sources
Recombinant mumps virus as a cancer therapeutic agent
Mumps virus belongs to the family of Paramyxoviridae and has the potential to be an oncolytic agent. Mumps virus Urabe strain had been tested in the clinical setting as a treatment for human cancer four decades ago in Japan.
Arun Ammayappan+2 more
doaj +2 more sources
Easy and Rapid Detection of Mumps Virus by Live Fluorescent Visualization of Virus-Infected Cells. [PDF]
Mumps viruses show diverse cytopathic effects (CPEs) of infected cells and viral plaque formation (no CPE or no plaque formation in some cases) depending on the viral strain, highlighting the difficulty in mumps laboratory studies. In our previous study,
Tadanobu Takahashi+13 more
doaj +2 more sources
Emergent lineages of mumps virus suggest the need for a polyvalent vaccine
Mumps outbreaks among vaccinated patients have become increasingly common in recent years. While there are multiple conditions driving this re-emergence, convention has suggested that these outbreaks are associated with waning immunity rather than ...
Meghan May+2 more
doaj +2 more sources
Mumps Virus: Modification of the Identify-Isolate-Inform Tool for Frontline Healthcare Providers
Mumps is a highly contagious viral infection that became rare in most industrialized countries following the introduction of measles-mumps-rubella (MMR) vaccine in 1967.
Kristi L. Koenig+4 more
doaj +2 more sources
Molecular mechanisms of stress-induced reactivation in mumps virus condensates.
Zhang X+12 more
europepmc +2 more sources
Deep sequencing reveals persistence of cell-associated mumps vaccine virus in chronic encephalitis. [PDF]
Routine childhood vaccination against measles, mumps and rubella has virtually abolished virus-related morbidity and mortality. Notwithstanding this, we describe here devastating neurological complications associated with the detection of live-attenuated
Breuer, J+20 more
core +3 more sources
Genetic characteristic of mumps virus from 2012 to 2016 and its serum antibody level among general healthy population during 2018-2020 in Jiangsu Province, China. [PDF]
Mumps is a vaccine-preventable disease with high contagious capability. Its incidence declined rapidly since one dose of mumps vaccine was introduced into Expanded Program of Immunization (EPI) in 2008 in China. Nonetheless, the outbreaks of mumps remain
Deng X, Hu Y, Lu P, Wang Z, Guo H.
europepmc +2 more sources
Current Status of Mumps Virus Infection: Epidemiology, Pathogenesis, and Vaccine. [PDF]
Mumps is an important childhood infectious disease caused by mumps virus (MuV). We reviewed the epidemiology, pathogenesis, and vaccine development of mumps.
Su SB, Chang HL, Chen AK.
europepmc +2 more sources