Results 111 to 120 of about 215,693 (303)
In this study, we constructed a nanoparticle that was CD4 antibody‐mediated targeted, Fut7‐expressing plasmid‐loaded cationic liposome, namely CD4‐LDP‐Fut7. Upregulation of Fut7 expression in Tregs by using CD4‐LDP‐Fut7 can increase Treg homing to the intestine, thereby facilitating repair of the intestinal epithelial barrier and inhibiting ...
Qian Zhou +13 more
wiley +1 more source
Wedelolactone (WED), a natural TLR2 agonist, promotes neutrophil differentiation and enhances bactericidal function, offering a potential therapeutic strategy for neutropenia. Using a multi‐omics approach, this study reveals that WED activates the TLR2/MEK/ERK pathway, upregulating key transcription factors (PU.1, CEBPβ) to drive neutrophil development.
Long Wang +16 more
wiley +1 more source
Application of Internal Revenue Code Section 103(C) to Variable Rate Demand Bonds: Purging the Profiteering Potential [PDF]
This Note analyzes transactions involving VRDBs, to determine whether they comply with the strictures of IRC section 103(c) and, hence, qualify for the tax exemption. Initially, this Note provides an overview of the tax-exempt bond market by examining
Hellenbrand, Troy M.
core +1 more source
Testicular mRNA‐LNP Delivery: A Novel Therapy for Genetic Spermatogenic Disorders
In the current study, we developed a novel therapy for genetic spermatogenic disorders. It was revealed that in vivo delivery of mRNA LNP3 could restore spermatogenesis in Msh5D486Y/D486Y and Maps KO mouse models with meiotic arrest. Notably, the offspring without genomic integration was born using ICSI derived from the rescue of Msh5D486Y/D486Y mouse ...
Chenwang Zhang +22 more
wiley +1 more source
Tax Reform and the Market For Tax-Exempt Debt [PDF]
This paper provides clear evidence that the yield spread between long-term taxable and tax-exempt bonds responds to changes in expected individual tax rates, a finding that refutes theories of municipal bond pricing that focus exclusively on commercial ...
James M. Poterba
core
The Tax Provisions in the American Recovery and Reinvestment Act [PDF]
This report provides a detailed look at the tax provisions in the ARRA, noting which current laws are affected and the costs of ...
Shawn Fremstad
core
Magnetic Anisotropy Modulation via van der Waals Gap Engineering in 2D Ferromagnet Fe4GeTe2
This study demonstrates a new route to control magnetic anisotropy in 2D ferromagnets via van der Waals gap engineering. In Fe4GeTe2, an interface‐induced vdW gap expansion is found to anomalously enhance in‐plane magnetic anisotropy while suppressing the spin reorientation transition.
Weiran Xie +13 more
wiley +1 more source
Shades of green: Unveiling the impact of municipal green bonds on the environment
Green bonds allocate proceeds towards environmentally beneficial projects and sustainable development goals, distinguishing themselves from traditional bonds primarily in the use of proceeds determination.
Marta Campi +2 more
doaj +1 more source
Enhancing the Security Behind Municipal Obligations: Flushing and U.S. Trust Lead the Way [PDF]
When bond counsel\u27 render their legal opinion approving the issuance and delivery of a municipal obligation, one of the opinions traditionally expressed is that the obligation is valid and legally binding according to its terms.
Bond, Kenneth W.
core +1 more source
This study revealed how the osteoblastic microenvironment determines the fate of cancer cells disseminated in bone, with a focus on whether they colonize, reside in quiescence, or reactivate from dormancy. Targeting integrin signaling may offer promising strategies for preventing quiescent cancer cells reactivation and bone colonization.
Hong‐Li Wang +7 more
wiley +1 more source

