Results 131 to 140 of about 653,490 (294)

Dynamics of the Mammalian Placental Metabolome in Placentogenesis and Embryonic Development

open access: yesAdvanced Science, EarlyView.
This study identifies three metabolic stages (E8.5, E9.5–10.5, E11.5–14.5) and two transition periods (E8.5–9.5, E10.5–11.5) in mouse placental development. NAD(H) emerges as a key dynamic metabolite that enhances embryonic growth through accelerated segmentation and increased proliferation of mouse embryonic stem cell (mESC)‐induced presomitic ...
Gang Chen   +11 more
wiley   +1 more source

Municipalities secession and uncertainty on public goods provision [PDF]

open access: yes
This paper investigates the causes of municipalities secession in Brazil. The theoretical modelproposes that the median voter is not fully informed about the efficiency effect of secession on publicgood provision and uses the break up decision undertaken
Arvate, Paulo Roberto   +2 more
core  

Highly Resolved Community Sewage Metagenomics Unveiling Landscape and Transmission Patterns of Antibiotic Resistome in Hong Kong Populations

open access: yesAdvanced Science, EarlyView.
A large‐scale, high‐resolution antimicrobial resistance (AMR) surveillance in Hong Kong community sewage combining short‐ and long‐read sequencing. The resistome profile is comprehensively characterized, and this upstream sampling strategy demonstrated superiority in reflecting the human gut resistome.
Jiahui Ding   +11 more
wiley   +1 more source

Using Spatial Econometrics to Analyze Local Growth in Sweden [PDF]

open access: yes
This paper investigates factors that determine the average income growth and net migration rates in Swedish municipalities during the period 1981 to 1999.
Johan Lundberg
core  

Remimazolam Ameliorates Autistic‐Like Behaviors via Suppression of Ferroptosis in VTA Dopaminergic Neurons in a Mouse Model of ASD

open access: yesAdvanced Science, EarlyView.
The ultra‐short‐acting sedative remimazolam has a sustained therapeutic effect on the core symptoms of VPA‐exposed mice. Remimazolam, a GABA agonist, exerts its therapeutic effects by protecting dopamine neurons in the VTA of VPA‐exposed mice. Meanwhile, ferroptosis is the critical mechanism by which remimazolam protects VTA dopaminergic neurons and ...
Yuxin Zhang   +7 more
wiley   +1 more source

AN ESTIMATION OF DISPOSABLE PERSONAL INCOME OF THE SPANISH MUNICIPALITIES IN 1997 [PDF]

open access: yes
Since 1992, Lawrence R. Klein Institute –Autónoma University of Madrid- estimates the disposable income of the Spanish municipalities, recently published in the ‘Anuario Comercial de España’ –Spanish Trade Yearbook- as scaled levels.
Coro Chasco-Yrigoyen
core  

The Utility of Trouble: Municipal Health Care and the GIC: Success and Limitations [PDF]

open access: yes, 2010
Reports first-year outcomes and savings from municipalities' unions and retirees joining the Group Insurance Commission, as well as barriers to progress, including negotiation requirements and lack of flexibility allowing municipalities to manage ...

core  

Tim1 Deficiency Mediates Gestational Hyperglycemia‐Related Syncytiotrophoblast Dysfunction and Fetal Growth Restriction

open access: yesAdvanced Science, EarlyView.
Hyperglycemia during pregnancy impairs the fusion of trophoblast cells into syncytiotrophoblasts, leading to fetal growth restriction. This impaired fusion is mediated by Tim1 downregulation via hyperglycemia‐induced ROS. Antioxidant therapy during pregnancy promotes syncytiotrophoblast formation by upregulating Tim1 expression, thus alleviating fetal ...
Junsen She   +14 more
wiley   +1 more source

El Proyecto Municip@ El Proyecto Municip@

open access: yesPolítica y Sociedad, 2010
Desde los años noventa del siglo pasado las administraciones públicas españolas se vieron inmersas en un proceso de transformación que no sólo afectó a sus estructuras internas sino también a su modelo de relación con los ciudadanos. Dentro de este contexto de cambio, las tecnologías de la información y comunicación (TIC) e Internet se destacaron como ...
Gema Pastor Albaladejo   +1 more
openaire   +1 more source

Reform of Financing of Municipalities in Slovenia [PDF]

open access: yes
The article presents a comparison of the Slovenian Financing of Municipalities Act, which had been in force since April 20062, and the new act, which entered into force on 1st January 20072.The main question asked is how the changed formula for ...
Franci Zohar
core  

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