Results 81 to 90 of about 653,490 (294)

Biomimetic Copper‐Doped Nano‐Aluminum Adjuvant Potentiates Therapy in Chemoresistant Acute Myeloid Leukemia

open access: yesAdvanced Healthcare Materials, EarlyView.
We developed a novel copper‐doped aluminum nano‐adjuvant (CuNA) to overcome cytarabine resistance in acute myeloid leukemia (AML). CuNA effectively sensitizes drug‐resistant AML cells to cytarabine by inducing mitochondrial dysfunction and inhibiting HMGCR/GPX4 to amplify ferroptosis.
Chao He   +10 more
wiley   +1 more source

Liquidity Values in Municipal Accounting in the Czech Republic

open access: yesJournal of Competitiveness, 2019
The aim of this paper is to present the results of a study which analyzes the use of liquidity management among municipalities within the Czech Republic.
Milana Otrusinova, Alena Kulleova
doaj   +1 more source

Interfacial Bioengineering of Dynamic Networks Hybrid Hydrogel for Programmed Intervention in Oral Precancerous Epithelial States

open access: yesAdvanced Healthcare Materials, EarlyView.
This study develops a dual‐bioinspired hydrogel, MSA@PGel (macrophage membrane‐coated and salvianolic acid B/5‐aminolevulinic acid co‐loaded liposomes embedded in a polydopamine‐based gel), that integrates macrophage membrane‐mediated active targeting and mussel‐inspired wet adhesion for programmed intervention in oral precancerous lesions.
Xiaoxian Zhao   +8 more
wiley   +1 more source

Too many municipalities? [PDF]

open access: yesRevista Brasileira de Economia, 2011
Does democracy lead to the creation of too many municipalities? We analyze this issue within the context of the Alesina e Spolaore (1997) model where the quality of municipal services deteriorates with the distance from the center of a municipality. Individuals can vote in a referendum to split an existing municipality. We show that social welfare will
openaire   +4 more sources

Macrophage Membrane‐Cloaked, ROS‐Triggered Quercetin Nanocarriers Target Ovarian Lesions to Treat Polycystic Ovary Syndrome

open access: yesAdvanced Healthcare Materials, EarlyView.
The synthesis process of MM@PCD@QNPs and its potential mechanism for treating PCOS. (A) Assembly steps of MM@PCD@QNPs. (B) Synthesis and decomposition of MM@PCD@QNPs. (C) Potential therapeutic mechanisms of MM@PCD@QNPs for PCOS. PCD, PABP conjugated with DEX polymer; QUR, quercetin; CDI, N, N′‐carbonyldiimidazole; DEX, dextran; PABP, 4‐(hydroxymethyl ...
Wenzhu Li   +9 more
wiley   +1 more source

Hybrid energy harvesting using piezoelectric footsteps and solar panels to ensure clarity

open access: yesResults in Engineering
Renewable energy sources significantly influence urban growth and mitigate global warming. These systems have the capability to achieve complete development of the region and function to mitigate carbon oxide emissions from power producing facilities ...
O. Hussein   +4 more
doaj   +1 more source

Local Governments in the Wake of Demographic Change: Efficiency and Economies of Scale in German Municipalities [PDF]

open access: yes
German municipalities are expected to suffer from (often significant) population losses in the upcoming decades. We assess these local governments? vulnerability to the fiscal consequences of this demographic decline through two means (using a sample of ...
Geys, Benny   +2 more
core  

Wound Geometry Determines Whether Aligned‐Fiber Scaffolds Accelerate or Impede Diabetic Wound Healing: A Biased Random Walk Analysis

open access: yesAdvanced Healthcare Materials, EarlyView.
Wound closure is governed by geometry‐orientation coupling: aligned fibers speed migration along their axis but hinder perpendicular advance. In vivo diabetic wound experiments with composition‐matched fibrin, combined with an anisotropic diffusion (biased random‐walk) model, quantify this trade‐off and generate a healing landscape.
Yin‐Yuan Huang   +13 more
wiley   +1 more source

Explaining Sunday shop policies [PDF]

open access: yes
Dutch municipalities have the right to decide on Sunday shop opening hours since 1996. Despite positive effects on economic growth and employment, many municipalities restrict Sunday trading in one way or another.
Elbert Dijkgraaf, Raymond Gradus
core  

Organic school meals in three Danish municipalities [PDF]

open access: yes, 2008
In order to prevent children and young people from becoming overweight or obese, it is imperative to promote healthier eating patterns. So it is necessary to develop and implement effective strategies that can influence the eating and lifestyle habits of
He, Chen
core  

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