Results 121 to 130 of about 1,668 (284)

Closed‐Loop Decoding and Intervention of Pain: A Novel BMI Strategy Integrating θ‐Band Detection and Mechano‐Electro‐Biological Coupled Hydrogels

open access: yesAdvanced Science, EarlyView.
A closed‐loop brain–machine interface with a PFAPT hydrogel electrode identifies prefrontal θ‐band as a neuropathic pain biomarker. The hydrogel enables stable 28 d ECoG recording and delivers θ‐triggered cortical stimulation, alleviating pain and affective behaviors in rats via bidirectional regulation of inflammation and central sensitization ...
Yun Ji   +17 more
wiley   +1 more source

Ovarian Cancer Diagnosis and Chemoresistance Prediction Model Based on cfRNA Molecular Signature

open access: yesAdvanced Science, EarlyView.
A deep learning model analyzes cfRNA profiles extracted from the blood of OVCA patients. This innovative approach distinguishes OVCA from healthy controls with high accuracy. Crucially, it reliably predicts patient response to chemotherapy (sensitive versus resistant subgroups).
Qinhao Guo   +14 more
wiley   +1 more source

Reimagining ownership and governance for carbon dioxide removal (CDR): exploring existing alternative models to advance equity and justice

open access: yesCarbon Management
Carbon dioxide removal (CDR) technologies are rapidly transitioning from research to real-world application. At present, private-sector oriented logics for CDR deployment dominate—a primacy that poses several risks for just and equitable outcomes.
Giulia Belotti   +3 more
doaj   +1 more source

REGγ Suppresses Ferroptosis and Induces Drug Resistance by Degrading WDR6 in Chondrosarcoma

open access: yesAdvanced Science, EarlyView.
Here, we identified REGγ as a susceptibility factor in chondrosarcoma. Our study demonstrates that abnormally activated REGγ‐20S proteasome promotes chondrosarcoma development and progression. Further validation in animal models revealed that blocking REGγ function induced ferroptosis, suppressed malignant progression of chondrosarcoma, and uncovered a
Fanrong Liu   +20 more
wiley   +1 more source

Adoção de “Sistema Privado de Ensino”: análise de dois municípios paulistas

open access: yesEducação: Teoria e Prática, 2013
This article aims to analyze the process of adopting the "private system of education" in two counties, with a view to teaching autonomy against the curriculum standards.
Rosilene Rodrigues da Silva Souza   +1 more
doaj  

Provincial dances theatre: From a local project to a flagship of contemporary choreography in 35 years

open access: yesУправление культурой
The article is devoted to the consideration of the phenomenon of the domestic dance theater, which appeared in Russia in the early 1990s, and one of the iconic representatives of which is the Yekaterinburg troupe "Provincial Dances".
Natalia V. Kuryumova
doaj   +1 more source

An Anterior Cingulate Cortex‐Anterior Insular Cortex Glutamatergic Circuit Gates Stress‐Induced Visceral Hypersensitivity and Anxiety via Ionotropic Glutamate Receptors Trafficking

open access: yesAdvanced Science, EarlyView.
This study identifies an anterior cingulate cortex (ACC) to anterior insular cortex (AIC) glutamatergic (Glu) circuit that gates stress induced visceral hypersensitivity and anxiety. Circuit activation induces both phenotypes, whereas inhibition relieves them.
Junwen Wang   +8 more
wiley   +1 more source

Adoption of a Photocopied Course Packet Teaching System in Ipeuna, Sao Paulo, Brazil

open access: yesEducação: Teoria e Prática, 2011
This work investigated and analyzed the adoption the consequences of the publicprivate partnership the town of Ipeuna, in the state of Sao Paulo, with regard to the adoption of a photocopied course packet teaching system.
Alessandra Aparecida Cain
doaj  

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