Type III flagellar protein export and flagellar assembly [PDF]
Bacterial flagella, unlike eukaryotic flagella, are largely external to the cell and therefore many of their subunits have to be exported. Export is ATP-driven. In Salmonella, the bacterium on which this chapter largely focuses, the apparatus responsible
Macnab, Robert M.
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Enhanced Epithelial Cell Uptake of Glycol Chitosan‐Coated PLGA Nanoparticles for Oral Drug Delivery
Here, glycol chitosan (GC)‐coated PLGA NPs are developed to enhance oral drug delivery by enabling dual‐pathway endocytosis via clathrin‐ and caveolae‐mediated mechanisms. Alginate layering coating on GC‐PLGA further improves oral insulin delivery, achieving sustained glucose reduction in diabetic mice.
Huiwen Pang+7 more
wiley +1 more source
Interleukin‐18 signaling promotes activation of hepatic stellate cells in mouse liver fibrosis
Interleukin‐18 signaling promotes activation of hepatic stellate cells in mouse liver fibrosis. Abstract Background and Aims Nucleotide‐binding oligomerization domain‐like receptor‐family pyrin domain‐containing 3 (NLRP3) inflammasome activation has been shown to result in liver fibrosis.
Jana Knorr+19 more
wiley +1 more source
Apocrine glands in the eyelid of primates contribute to the ocular host defense [PDF]
Apocrine glands of Moll are regular components of primate eyelids. We studied the distribution and localization of these glands in three different primate species, the common marmoset, the rhesus monkey, and the hamadryas baboon.
Stoeckelhuber, B. M.+2 more
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FUS Selectively Facilitates circRNAs Packing into Small Extracellular Vesicles within Hypoxia Neuron
This study aimed to unravel the role of FUS in the loading of functional circRNAs into neuronal sEVs under hypoxic conditions, which involves their aggregations in SGs and specific interaction between the FUS Zf_RanBP domain to regulate circRNA sorting in sEVs.
Jiankun Zang+14 more
wiley +1 more source
Distribution and composition of the lysis cassette of Lactococcus lactis phages and functional analysis of bacteriophage ul36 holin [PDF]
The bacteriophage lysis cassette, which comprises a lysin and a holin gene, was analyzed in 18 Lactococcus lactis phages. A muramidase motif was found in the lysins of c2-like phages, while an amidase motif was observed in the lysins of 936-like phages ...
Labrie, Steve+3 more
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Inducing persistent flow disturbances accelerates atherogenesis and promotes thin cap fibroatheroma development in D374Y-PCSK9 hypercholesterolemic minipigs [PDF]
BACKGROUND: -Although disturbed flow is thought to play a central role in the development of advanced coronary atherosclerotic plaques, no causal relationship has been established.
Andersen, NP+21 more
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Microbiome Single Cell Atlases Generated with a Commercial Instrument
Single cell sequencing is valuable for dissecting complex systems and uncovering unique features in individual cell types. However, tools for single cell microbial analysis are limited. Easily Accessible Single microbe sequencing (EASi‐seq), which adapts a commercially available single cell platform for efficient sequencing of single microbial genomes ...
Xiangpeng Li+8 more
wiley +1 more source
An investigation to observe the effect of DMSO and glycerol on the aggregation of lysozyme [PDF]
Huntington’s disease, Parkinson’s disease, Alzheimer’s disease, Prions Disease are few among many diseases caused due to the aggregation of misfolded proteins, which eventually leads to the formation of amyloids.
Sahoo, A K
core
Muramidase Activity in Leukemic Rats
Summary1. Greatly elevated serum and urine muramidase levels were observed in rats with transplanted chloroleukemia. 2. In one chloroleukemic rat with ascites, the fluid had a very high muramidase content. 3. Homogenates of chloroma cells consisting of myeloblasts and promyelocytes had very high muramidase activity. 4.
William C. Moloney, David S. Rosenthal
openaire +2 more sources