Implantable drug delivery system: Frontiers of medicine‐engineering interdisciplinary
Interdisciplinary Medicine, EarlyView.This review systematically summarizes the driving mechanisms of implantable on‐demand drug delivery systems (IDDS), including endogenous, exogenous, and closed‐loop strategies. It highlights the pivotal roles of flexible electronics and miniaturization in enhancing the tissue conformity and spatial adaptability.
Yu Zeng +9 more
wiley +1 more source
<b>Self-aggregating</b> <i><b>Lactiplantibacillus plantarum</b></i> <b>enhances type-I interferon responses via the cytosolic sensors NOD2 and cGAS</b>. [PDF]
Gut MicrobesSolis S +6 more
europepmc +1 more source
Artificial cell: An emerging bioactive material with advanced applications in cancer theranostics
Interdisciplinary Medicine, EarlyView.Artificial cells are emerging as attractive biomimetic bioactive materials that recapitulate key structures and functions of natural cells. This review systematically summarizes their major types, versatile fabrication strategies, tuneable properties and programmable biomimetic behaviours, highlights their cutting‐edge integrated applications in cancer
Daikun Wu, Shuo Yang, Hongjing Dou
wiley +1 more source
Peptidoglycan recycling is critical for cell division, cell wall integrity, and β-lactam resistance in <i>Caulobacter crescentus</i>. [PDF]
ElifeRichter P +7 more
europepmc +1 more source
Mapping the subgingival HerBiome and HisBiome over the human healthspan
Journal of Periodontology, EarlyView.Abstract Background Understanding the intricate relationship between sex, age, and the oral microbiome is crucial for deciphering the onset and progression of numerous age‐related oral and systemic diseases. Methods Subgingival plaque was collected from 781 periodontally and systemically healthy females and 160 males spanning 0 to 80 years.
Rahul Nikam +3 more
wiley +1 more source
Beyond Direct Fibrinolysis: Novel Approaches to Thrombolysis. [PDF]
Pharmaceuticals (Basel)Shibeko AM +4 more
europepmc +1 more source
Maintaining egg freshness in the absence of refrigeration: The potential of zero‐energy cooling pots
JSFA reports, EarlyView.Abstract Background Egg storage in regions with unreliable electricity is challenging, leading to rapid quality deterioration and postharvest losses. This study evaluated the efficacy of a Zero‐Energy Cooling (ZEC) pot, an evaporative cooling technology, for preserving table egg quality in comparison to conventional refrigeration and ambient storage ...
Thomas Ansong Agyei +4 more
wiley +1 more source
Bio‐Inspired, Zwitterionic Copolymers with Amphiphilic Character
Macromolecular Rapid Communications, EarlyView.Zwitterionic copolymers based on arginine‐derived monomers are produced by xanthate‐supported photo‐iniferter reversible‐addition‐fragmentation chain‐transfer polymerization. Experiments in relevant conditions show that the designed (co)polymers hardly interact with biologically relevant proteins and enzymes such as bovine serum albumine (BSA), fetal ...
Theresa M. Lutz +4 more
wiley +1 more source
Phage endolysins as alternative antimicrobials: mechanisms, clinical progress, and emerging resistance frameworks. [PDF]
Front MicrobiolQian H, Zheng Y.
europepmc +1 more source
Ion Activation Methods for Top‐Down Proteomics
Mass Spectrometry Reviews, EarlyView.ABSTRACT Mass spectrometry (MS) has emerged as a premier method used to characterize the sequences of proteins. Top‐down proteomics aims to capture the multiple sources of structural diversity reflected in proteins, such as those that arise from alternative RNA splicing events or the addition of post‐translational modifications. Tandem MS (i.e., MS/MS)
Jada N. Walker, Jennifer S. Brodbelt
wiley +1 more source