Results 101 to 110 of about 8,976 (288)

Discovery of chlamydial peptidoglycan reveals bacteria with murein sacculi but without FtsZ [PDF]

, 2013
Chlamydiae are important pathogens and symbionts with unique cell biological features. They lack the cell-division protein FtsZ, and the existence of peptidoglycan (PG) in their cell wall has been highly controversial.
Aistleitner, Karin, Biboy, Jacob, Brun, Yves V., Gray, Joe, Hall, Edward, Horn, Matthias, Jensen, Grant J., Kuru, Erkin, Pilhofer, Martin, VanNieuwenhze, Michael S., Vollmer, Waldemar   +10 more
core   +2 more sources

Endocytic Control of Cell‐Autonomous and Non‐Cell‐Autonomous Functions of p53

Advanced Science, EarlyView.
NUMB Ex3‐containing isoforms localize to the plasma membrane, where they recruit p53 through SNX9 and direct it to multivesicular bodies and exosomes. Exported p53 is taken up by neighboring cells and activates nuclear programs, revealing an intercellular, exosome‐based pathway that might help establish a tumor‐suppressive microenvironment.
Roberta Cacciatore, Andrea Basile, Stefano Freddi, Irene Schiano Lomoriello, Carlo Ribelle Zucca, Giuseppe Ciossani, Luigi Scietti, Alessandro Cuomo, Simona Ronzoni, Simone Pelicci, Mario Faretta, Elena Zaccheroni, Giuliana Pelicci, Vittoria Matafora, Angela Bachi, Rosalind Helen Gunby, Salvatore Pece, Sara Sigismund, Letizia Lanzetti, Ivan Nicola Colaluca, Pier Paolo Di Fiore   +20 more
wiley   +1 more source

Enhanced antibacterial activity of Acinetobacter baumannii bacteriophage ØABP-01 endolysin (LysABP-01) in combination with colistin

Frontiers in Microbiology, 2016
Endolysins are lytic enzymes produced by bacteriophages with their ability to degrade the cell wall of bacterial hosts. Endolysin (LysABP-01) from A. baumannii bacteriophage ØABP-01 was cloned, overexpressed and characterized.
Rapee Thummeepak, Thawatchai Kitti, Duangkamol Kunthalert, Duangkamol Kunthalert, Sutthirat Sitthisak, Sutthirat Sitthisak   +5 more
doaj   +1 more source

Changes in physiological and immunological parameters during the peripartum period in Zwerasca sheep [PDF]

, 2014
The aim of this study was to provide the picture of the dynamics of some blood parameters in the native Zerasca sheep breed during the peripartum period.
Alfieri, L., Benvenuti, M.N., Cavallina, R., Giuliotti, L., Lai, O., Rabusca, G.   +5 more
core   +1 more source

Differentiation of Muramidase and  -Lysin

Experimental Biology and Medicine, 1966
SummaryAlthough β-lysin and muramidase are similar in their bacterial spectrum, heat stability, and adsorption by bentonite on an asbestos-cellulose filter pad of the Seitz type, they differ in other respects. β-lysin is relatively more effective as a bactericidal agent for Bacillus subtilis than for Micrococ-cus lysodeikticus.
D. M. Donaldson, J. G. Tew
openaire   +1 more source

De Novo Multi‐Mechanism Antimicrobial Peptide Design via Multimodal Deep Learning

Advanced Science, EarlyView.
Current AI‐driven peptide discovery often overlooks complex structural data. This study presents M3‐CAD, a generative pipeline that leverages 3D voxel coloring and a massive database of over 12 000 peptides to capture nuanced physicochemical contexts.
Xiaojuan Li, Haifan Gong, Yue Wang, Yinuo Zhao, Lixiang Li, Peijing Bao, Qingzhou Kong, Jialu Fu, Boyao Wan, Yumeng Zhang, Jinghui Zhang, Jiekun Ni, Zhongxue Han, Xueping Nan, Kunping Ju, Longfei Sun, Yuerui Ma, Huijun Chang, Mengqi Zheng, Yanbo Yu, Xiaoyun Yang, Xiuli Zuo, Haina Wang, Yanqing Li   +23 more
wiley   +1 more source

Methods for microbiological and immunological studies of space flight crews [PDF]

Systematic laboratory procedures compiled as an outgrowth of a joint U.S./U.S.S.R. microbiological-immunological experiment performed during the Apollo-Soyuz Test Project space flight are presented.
Taylor, G. R., Zaloguev, S. N.
core   +1 more source

ZDHHC9‐Mediated Palmitoylation of ACSL4 Drives Ferroptosis in Diabetes Mellitus–Induced Erectile Dysfunction

Advanced Science, EarlyView.
ABSTRACT Diabetes mellitus‐induced erectile dysfunction (DMED) is a highly prevalent complication among diabetic patients; however, its underlying pathogenic mechanisms remain incompletely understood. Metabolic disorder is a hallmark of diabetes, yet its precise contribution to DMED progression is not well defined.
Wanyang Guo, Ming Xiao, Mengjun Huang, Dongzi Peng, Ruijiang Zeng, Ruilin Liu, Yuanqiao Zhao, Zhihan Ouyang, Yulong Hong, Zexian Ding, Zhuo Xing, Hao Su, Jinxiang Wang, Wenjun Mao, Xin Jin   +14 more
wiley   +1 more source

Autolysin N617 Deamidation as a Molecular Target of Chelerythrine in Methicillin-Resistant

Natural Product Communications
Objective Methicillin-resistant Staphylococcus aureus (MRSA) is a major clinical challenge due to its resistance to multiple antibiotics. Chelerythrine, a natural benzophenanthridine alkaloid, shows antibacterial activity against MRSA, but its precise ...
Jianhua Liao, Chunyan Meng, Baoqing Liu, Yuechun Wang, Jun Cheng   +4 more
doaj   +1 more source

Bifidobacterium Pseudolongum‐Derived Acetate Attenuates Acute Pancreatitis Through GPR43‐Mediated Suppression of M1 Macrophage Polarization

Advanced Science, EarlyView.
The severity of acute pancreatitis (AP) is linked to reduced abundance of Bifidobacterium pseudolongum (B. pseudolongum). Administration of B. pseudolongum or its key metabolite acetate alleviates pancreatic and systemic inflammation by suppressing M1 macrophage polarization.
Langyi Guan, Xueyang Li, Cong He, Pan Zheng, Yaoyu Zou, Qi Zhu, Xin Li, Jie Liang, Junmin Yang, Li Zhang, Yuman Ye, Jianhua Wan, Huajing Ke, Jianping Liu, Nonghua Lu, Nianshuang Li, Yin Zhu   +16 more
wiley   +1 more source