Results 181 to 190 of about 6,255 (235)

Inflammatory and Immunological Basis of Periodontal Diseases

Journal of Periodontal Research, EarlyView.
The periodontal lesion emerges as an evolving immunological battlefield, where host–microbiome interactions, dysregulated immune responses, fragile resolution mechanisms, and inflammophilic dysbiosis converge to shift the balance from homeostasis to unrestrained tissue destruction.
Giacomo Baima, Marion Arce, Mario Romandini, Thomas Van Dyke   +3 more
wiley   +1 more source

The Unique Capability of Endolysin to Tackle Antibiotic Resistance: Cracking the Barrier. [PDF]

J Xenobiot
Sabur A, Khan A, Borphukan B, Razzak A, Salimullah M, Khatun M.   +5 more
europepmc   +1 more source

The Keystone‐Pathogen Hypothesis Updated: The Role of Porphyromonas gingivalis in Periodontitis

Journal of Periodontal Research, EarlyView.
Porphyromonas gingivalis orchestrates a coordinated manipulation of immune and inflammatory responses in periodontal tissues which leads to the generation of a dysbiotic, subgingival biofilm community, and progression of periodontitis. The type 9 secretion system, lipid A modification, and the formation of outer membrane vesicles are important ...
Mike A. Curtis, James A. Garnett, Richard P. Darveau   +2 more
wiley   +1 more source

The Hemoprotein Hhy1 Promotes Heme‐Dependent Catalase Activity of Ctt1

Molecular Microbiology, EarlyView.
A Schizosaccharomyces pombe strain deficient in heme (hem1Δ) and siderophore (Fc) biosynthesis, as well as high‐affinity iron (Fe) uptake (blue), was used to uncover the hemoprotein Hhy1 that promotes the heme‐dependent activity of the catalase Ctt1. In contrast, hhy1Δ cells exhibit reduced Ctt1 activity and increased sensitivity to oxidative stress ...
Tobias Vahsen, Samuel Plante, Berthy Mbuya, Simon Labbé   +3 more
wiley   +1 more source

Macromolecular dimensions of a synthetic polyelectrolyte as a factor in its interactions with protein and cells: desirability for longer chains.

J Mater Chem B
Hlushko R, Marin A, Chowdhury A, Andrianov AK.   +3 more
europepmc   +1 more source

Structural and Biochemical Characterization of a New Phage-Encoded Muramidase, KTN6 Gp46. [PDF]

Phage (New Rochelle)
Sanz-Gaitero M, De Maesschalck V, Patel A, Longin H, Van Noort V, Rodriguez-Rubio L, van Ryne M, Danis-Wlodarczyk K, Drulis-Kawa Z, Mesnage S, van Raaij M, Lavigne R.   +11 more
europepmc   +1 more source

Metacaspases contribute to the cellular response to heat stress in a marine diatom

New Phytologist, EarlyView.
Summary Climate‐driven marine heatwaves (HW) are extreme, large‐scale events characterized by elevated ocean temperatures lasting from days to months. Despite their importance, little is known about the molecular mechanisms of algal response to marine HW. Recent studies suggest that metacaspases play an important role in thermotolerance.
Mai Sadeh, Daniella Schatz, Shifra Ben‐Dor, Avia Mizrachi, Shiri Graff van Creveld, Amichai Zafrin, Assaf Vardi   +6 more
wiley   +1 more source

Development of the HTRF assay to evaluate the auxin‐induced binding between TIR1 and IAA7

New Phytologist, EarlyView.
Summary Auxin plays diverse roles in plant growth and development, including sensing environmental changes. Quantifying the interaction between auxin coreceptors provides the molecular basis for cells to sense and adapt to environmental cues. Although several assays are available, a more high‐throughput method is necessary to efficiently evaluate the ...
Jekson Robertlee, Shinya Hagihara
wiley   +1 more source

Using CEST NMR to discover previously unobserved states on the free energy surface of proteins: Application to the L99A cavity mutant of T4 lysozyme. [PDF]

J Biol Chem
Tiwari VP, Khandave NP, Hansen DF, Bouvignies G, Kay LE, Vallurupalli P.   +5 more
europepmc   +1 more source

Salivary Proteomic Signatures in Pregnant Women With Excessive Gingival Bleeding

Oral Diseases, EarlyView.
ABSTRACT Objective This observational, cross‐sectional, and analytical study aimed to explore the pathophysiological mechanisms of gingivitis in pregnancy by analyzing the salivary proteomic profile according to gingival bleeding status. Materials and Methods Pregnant women at the 27th week of gestation or beyond were categorized into two groups: those
Gerson Aparecido Foratori‐Junior, Clovis Bergamin Griso, Amanda Borges Pirondi, Laura Teodoro de Marchi, Talita Mendes Oliveira Ventura, Larissa Tercilia Grizzo, Roosevelt da Silva Bastos, Alejandra Chaparro, Nagihan Bostanci, Marília Afonso Rabelo Buzalaf   +9 more
wiley   +1 more source