Results 211 to 220 of about 10,350 (333)

Dissecting Microscopic Colitis Immunopathophysiology: Insights From Basic Research

open access: yesUnited European Gastroenterology Journal, EarlyView.
ABSTRACT Microscopic colitis is an inflammatory bowel disease (IBD) comprising two clinically undiscernible entities: collagenous colitis and lymphocytic colitis. Collagenous colitis associates with HLA genes and displays a Th1/Tc1–Th17/Tc17 profile with pericryptal myofibroblast activity, water malabsorption and secondary fluid loss due to altered ...
Andreas Münch   +1 more
wiley   +1 more source

Control of bacterial cell wall autolysins by peptidoglycan crosslinking mode. [PDF]

open access: yesNat Commun
Alvarez L   +5 more
europepmc   +1 more source

Plasma POSTN Derived From Bile Proteome Is a Promising Biomarker for Cholangiocarcinoma With Efficacy Comparable and Complementary to CA19.9

open access: yesUnited European Gastroenterology Journal, EarlyView.
ABSTRACT Background Cholangiocarcinoma presents a global health challenge due to its increasing incidence and poor prognosis, primarily resulting from delayed diagnosis. There is an urgent need for a reliable biomarker to enhance early detection. Materials and Methods Patients with cholangiocarcinoma were enrolled into three cohorts: a discovery set (n 
Lichieh Julie Chu   +6 more
wiley   +1 more source

Unveiling the complex extra‐oral colonization pathways and pathogenic mechanisms of Fusobacterium nucleatum, a heterogeneous oral pathogen

open access: yesVIEW, EarlyView.
We summarize the taxonomic characteristics, capabilities to adhere to and invade host cells, extra‐oral ectopic colonization pathways, and major pathogenic mechanisms of Fusobacterium nucleatum, and explore the regulation of F. nucleatum’s pathogenesis, aiming to provide references and assistance for the development of clinical interventions and future
Zhiwei Guan, Houbao Qi, Qiang Feng
wiley   +1 more source

The mechanism of soluble peptidoglycan hydrolysis by an autolytic muramidase. A processive exodisaccharidase.

open access: hybrid, 1984
John F. Barrett   +3 more
openalex   +1 more source

Smart Temperature‐Sensitive Injectable Methylcellulose‐Based Hydrogels: Design and Optimization for Sustained Drug Release

open access: yesVIEW, EarlyView.
MC‐based thermoreversible hydrogels were prepared and characterized. The MC/PEG hydrogel demonstrated sustained release of Dox, with rapid gelation time and the feasibility of controlling the drug release rate with temperature changes. Wide‐spectrum biocompatibility of the MC/PEG hydrogel was demonstrated, along with its ability to significantly reduce
Francesca Persano   +8 more
wiley   +1 more source

Crystal structure of the engineered endolysin mtEC340M. [PDF]

open access: yesActa Crystallogr F Struct Biol Commun, 2023
Wang JM   +4 more
europepmc   +1 more source

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