Results 211 to 220 of about 6,945 (269)

The Effects of pH on Orientations of Adsorbed Lysozyme on Negatively Charged Surfaces. [PDF]

J Phys Chem B
Anhesini DA, de Souza Júnior RB, Caetano DLZ, Caruso IP, Cherstvy AG, de Carvalho SJ.   +5 more
europepmc   +1 more source

In silico prediction of novel effective combinational treatment of chronic pain in individual patients: A joint white paper of the H2020 QSPainRelief consortium

British Journal of Pharmacology, EarlyView.
Abstract Opioids are prescribed widely for chronic pain despite well‐recognised risks and variable long‐term benefit, reflecting the lack of effective alternatives for many patients. Combination therapies offer a promising strategy to enhance efficacy whilst reducing side effects.
André Mouraux, Solenn Gousset, Beltrán Alvarez, Monica Baiula, Wouter Bakker, Andrea Bedini, Monir Bertayli, Divakar Budda, Robert Carr, Elisabetta Cuna, Óscar Díaz, Nina Donner, Jesús Giraldo, Geert‐Jan Groeneveld, Berfin Gülave, David Guydan, Hemme Hijma, Rafael Maldonado, Pedro Renault, Carlos Rinaudo, Jeroen Elaissaiss‐Schaap, Athan Spiros, Sara Stoeber, Petri Takkala, Daan van Valkengoed, Coen van Hasselt, Elizabeth (Liesbeth) C.M. de Lange   +26 more
wiley   +1 more source

Proteomic identification of Acanthamoeba castellanii excretory-secretory proteins associated with Klebsiella pneumoniae capsule enlargement: a candidate role for C-type lysozyme. [PDF]

Parasite
Chen CH, Huang JM, Lin WC, Tsai CM, Hsieh HY, Wang YJ.   +5 more
europepmc   +1 more source

Gut microbiota as a novel therapeutic target for eating disorders and obesity

British Journal of Pharmacology, EarlyView.
The graphical abstract highlights the bidirectional interaction between the gut microbiota and central homeostatic and hedonic mechanisms regulating food intake, which contributes to overweight and obesity. It also illustrates emerging microbiota‐based biomarkers and therapeutic strategies (including prebiotics, probiotics, postbiotics, synbiotics and ...
Solveiga Samulėnaitė, Victor Mathis, Emmanuel Darcq, Aurelijus Burokas, Elena Martín‐García, Rafael Maldonado   +5 more
wiley   +1 more source

Thermodynamic characterisation of covalent ligand binding

British Journal of Pharmacology, EarlyView.
Background and Purpose Differential scanning fluorimetry (DSF) is a common and straightforward method to evaluate the thermal stability of proteins and has been heavily used for ligand binding characterisation as well as for screening. One class of compounds that is less typically evaluated by DSF are covalent binders.
Rebecca Hertzman, Maayan Lavie, Almog Nadir, Ronen Gabizon, Nir London   +4 more
wiley   +1 more source

A novel peptidoglycan deacetylase modulates daughter cell separation in E. coli. [PDF]

PLoS Genet
Hernández-Rocamora VM, Martorana AM, Belloso A, Ballesteros D, Zaccaria M, Perez AJ, Iorga BI, Abia D, Gray J, Breukink E, Xiao J, Pazos M, Polissi A, Vollmer W.   +13 more
europepmc   +1 more source

Targetoid ulcerating eruption in a previously healthy man. [PDF]

JAAD Case Rep
Giordano JA, Cohen OG, Flowers RH, Moore ME.   +3 more
europepmc   +1 more source

Combined effects of thermal stress and benzene or toluene exposure on the immune and reproductive disruption in Nile tilapia (Oreochromis niloticus). [PDF]

Sci Rep
AboElkhair HA, Amra EA, Elshaer FM, Soliman HAM, Sayed AEH.   +4 more
europepmc   +1 more source

Recombinant Extracellular Factor Protein of <i>Streptococcus suis</i> as Potential Candidate Protein for Antibodies Against <i>S. suis</i> Detection and Subunit Vaccine Development: <i>In Silico</i> and <i>In Vitro</i> Approaches. [PDF]

Vaccines (Basel)
Mitsuwan W, Saengsawang P, Boripun R, Rodríguez-Ortega MJ, Nwabor OF.   +4 more
europepmc   +1 more source

How phagocytic cells kill bacteria: Lessons from a professional killer. [PDF]

FEBS Open Bio
Lamrabet O, Cosson P.
europepmc   +1 more source