Fungal lysozyme leverages the gut microbiota to curb DSS-induced colitis
Colitis is characterized by colonic inflammation and impaired gut health. Both features aggravate obesity and insulin resistance. Host defense peptides (HDPs) are key regulators of gut homeostasis and generally malfunctioning in above-mentioned ...
Ida Søgaard Larsen+13 more
doaj +1 more source
Applications of Lysozyme, an Innate Immune Defense Factor, as an Alternative Antibiotic
Lysozyme is a ~14 kDa protein present in many mucosal secretions (tears, saliva, and mucus) and tissues of animals and plants, and plays an important role in the innate immunity, providing protection against bacteria, viruses, and fungi.
Patrizia Ferraboschi+2 more
doaj +1 more source
Pesticin displays muramidase activity [PDF]
Pesticin of Yersinia pestis is the only bacteriocin that converts sensitive cells to stable spheroplasts. The amino acid sequence of pesticin as derived from the nucleotide sequence shows no similarity to those of any of the bacteriocins. The unique properties of pesticin prompted an investigation of its mode of action.
Vollmer W+4 more
openaire +3 more sources
Role of glucose and CcpA in capsule expression and virulence of Streptococcus suis [PDF]
Streptococcus suis is one of the most important pathogens in pigs and is also an emerging zoonotic agent. After crossing the epithelial barrier, S. suis causes bacteraemia, resulting in meningitis, endocarditis and bronchopneumonia.
A. de Greeff+14 more
core +9 more sources
Rearing system, utility type and hens’ age as a factor modifying lysozyme's hydrolytic activity [PDF]
The aim of study was to analyze the impact of the utility type, age and rearing system of hens on egg quality traits and the enzymatic activity of egg albumen lysozyme (LA). The material consisted of 120 eggs from two genotypes of hens: Hy-Line Brown and
Karolina Wengerska+4 more
doaj +1 more source
This study evaluates peptidoglycan hydrolysis by a microbial muramidase from the fungus Acremonium alcalophilum in vitro and in the gastrointestinal tract of broiler chickens.
Carsten Østergaard Frederiksen+10 more
semanticscholar +1 more source
Evaluation of a microbial muramidase supplementation on growth performance, apparent ileal digestibility, and intestinal histology of broiler chickens [PDF]
The current study evaluated the effects of different inclusion levels of microbial muramidase (Muramidase 007, DSM Nutritional Products) on gastrointestinal functionality by determination of apparent ileal digestibility (AID) of nutrients, investigation ...
Goodarzi Boroojeni, F.+4 more
core +1 more source
Protection of pigs against challenge with virulent Streptococcus suis serotype 2 strains by a muramidase-released protein and extracellular factor vaccine [PDF]
The efficacy of a muramidase-released protein (MRP) and extracellular factor (EF) vaccine in preventing infection and disease in pigs challenged either with a homologous or a heterologous Streptococcus suis serotype 2 strain (MRP EF ) was compared with ...
Smith, H.E.+3 more
core +2 more sources
Physical Studies of Muramidase (Lysozyme)
A.J. Sophianopoulos+3 more
openaire +3 more sources
A lysozyme-like protein in Brucella abortus is involved in the early stages of intracellular replication [PDF]
Secretion of proteins in Gram-negative bacteria is a high-energy consuming process that requires the translocation across two membranes and a periplasmic space composed of a mesh like layer, the peptidoglycan.
Czibener, Cecilia+2 more
core +1 more source