Results 131 to 140 of about 282,371 (382)
Substituent‐Based Modulation of Self‐Assembly and Immunogenicity of Amphipathic Peptides
Advanced Science, EarlyView.This study systematically investigates how positional and subtle changes, such as substituents on the phenyl ring attached to short amphipathic peptides, influence their self‐assembly, fibril morphology, and immunogenic responses. ABSTRACT Self‐assembled peptide‐based biomaterials provide versatile platforms for biomedical uses, featuring customizable ...
Anirban Das +13 more
wiley +1 more source
Advanced Science, EarlyView.This study demonstrates that inflammatory stimuli induce the acetylation‐triggered, chaperone‐mediated autophagic degradation of ubiquitin‐specific peptidase 9 X‐linked (USP9X) in macrophages. USP9X acts as a macrophage “inflammation switch” after myocardial infarction (MI). USP9X loss destabilizes tumor necrosis factor receptor‐associated factor (TRAF)
Biqing Wang +7 more
wiley +1 more source
Records of the Australian Museum, 2020 Elucidation of the evolutionary history of the subgenus Mus, including the House Mouse Mus musculus, is essential to understanding species diversification mechanisms in the Indomalayan region, which is a global biodiversity hotspot.
Hitoshi Suzuki
doaj +1 more source
Advanced Science, EarlyView.This work introduces a study that identifies HMGCR as a novel target in TNBC and develops a light‐gated PROTAC nanomedicine. Upon irradiation, this agent selectively degrades HMGCR, reprogramming lipid metabolism to induce ferroptosis and potent antitumor immunity, thereby significantly enhancing photoimmunotherapy efficacy.
Tong Su +18 more
wiley +1 more source
The main indicators of biosecurity and presence of house mouse (Mus musculus L.) in animal husbandry facilities [PDF]
Biotechnology in Animal Husbandry, 2014 Analysis of biosecurity indicators at critical control points intend to prevent undesirable infections in technological chains of production. Product quality is the basis for defining a biosecurity plan under the HACCP concept.
Đedović Suzana +4 more
doaj
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT TSPEAR (chr. 21q22.3) encodes a protein involved in tooth development and is predominantly expressed in the enamel knot. Biallelic loss of function variants in TSPEAR cause ectodermal dysplasia, tooth agenesis and sensorineural hearing loss. However, the role of TSPEAR in auditory processes is unclear.
Debora Vergani +17 more
wiley +1 more source
UJI INFUSA DAUN MALAKA (PHYLLANTHUS EMBLICA) TERHADAP KADAR KOLESTEROL DARAH MENCIT (MUS MUSCULUS) YANG HIPERKOLESTEROLEMIA [PDF]
, 2015 UJI INFUSA DAUN MALAKA (Phyllanthus emblica) TERHADAP KADAR KOLESTEROL DARAH MENCIT (Mus musculus) YANG HIPERKOLESTEROLEMIAABSTRAKPenelitian ini bertujuan mengetahui uji infusa daun malaka (Phyllanthus emblica) terhadap kadar kolesterol darah mencit (Mus
Sartika Silvana
core
Pengaruh Ekstrak Kangkung Air (Ipomoea Aquatica) Terhadap Efek Sedasi pada Mencit (Mus Musculus)
, 2022 Rizka Aldhayanti Suni +4 more
openalex +2 more sources
Generating golden Syrian hamsters with conditional alleles via zygote microinjection of CRISPR/Cas9
Animal Models and Experimental Medicine, EarlyView.We established the first conditional knockout (cKO) model in the golden Syrian hamster by CRISPR/Cas9‐mediated genome editing. Cas9 protein, two sgRNAs, and a donor plasmid carrying loxP‐flanked exon 2 of the ApoF gene were microinjected into one‐cell embryos. The floxed allele was efficiently generated (up to 27%) and transmitted through the germline.
Wei Chen +16 more
wiley +1 more source