Results 71 to 80 of about 205,850 (349)

Zinc Exposure Causes Disulfidptosis to Induce Miscarriage by Up‐Regulating GATA1/METTL1/SLC7A11 Axis

Advanced Science, EarlyView.
Zn exposure up‐regulates GATA1, promoting GATA1‐mediated METTL1 and SLC7A11 transcription. It also enhances METTL1‐mediated m7G modification on SLC7A11 mRNA, increasing SLC7A11 mRNA stability. Ultimately, Zn exposure up‐regulates SLC7A11 at both transcriptional and post‐transcriptional levels, causing disulfidptosis. Knockdown of murine Slc7a11, Gata1,
Wenxin Huang, Yi Sun, Yanxin Wang, Haijun Yan, Xiaoping Yue, Weidong Wu, Xueyu Chen, Jinfang Zhang, Yanbing Lin, Qiong Lei, Nan Ji, Shuaishuai Xing, Liqin Zeng, Qingzheng Kang, Depeng Zhao, Geng Guo, Huidong Zhang   +16 more
wiley   +1 more source

Localização de Schistosoma mansoni no plexo porta de Mus musculus experimentalmente infectados por um só sexo do trematódeo Localization of Schistosoma mansoni in the portal system of Mus musculus infected experimentally by a single sex of the trematode

Revista de Saúde Pública, 1982
Foi estudado o hábito migratório de Schistosoma mansoni em infecções bissexuais e nas produzidas por um só sexo do trematódeo, tendo sido evidenciada a influência do sexo no deslocamento dos esquistossomos.
Eliana Maria Zanotti, Luiz Augusto Magalhães, Aquiles Eugenico Piedrabuena   +2 more
doaj   +1 more source

Nine-day continuous recording of EEG and 2-hour of high-density EEG under chronic sleep restriction in mice

Scientific Data, 2022
Measurement(s) electroencephalography (EEG) Technology Type(s) electroencephalography (EEG) Factor Type(s) Chronic sleep restriction Sample Characteristic - Organism Mus ...
Hio-Been Han, Bowon Kim, Youngsoo Kim, Yong Jeong, Jee Hyun Choi   +4 more
doaj   +1 more source

Neuid: A Novel Neuron‐Enriched LncRNA that Connects Epigenetic Gene Silencing to Alzheimer's Disease

Advanced Science, EarlyView.
ABSTRACT The increasing evidence that non‐coding RNAs can become deregulated during pathogenesis is dramatically expanding the space for drug discovery beyond the protein‐coding genome. Long noncoding RNAs (lncRNAs) are emerging as key regulators of cellular function, yet most remain uncharacterized.
Ranjit Pradhan, Zorica Petrovic, M. Sadman Sakib, Sophie Schröder, Dennis Manfred Krüger, Tonatiuh Pena, Eren Diniz, Susanne Burkhardt, Anna‐Lena Schütz, Verena Gisa, Iga Grzadzielewska, Karl Toischer, Thor D. Stein, Jan Krzysztof Blusztajn, Ivana Delalle, Jelena Radulovic, Farahnaz Sananbenesi, Andre Fischer   +17 more
wiley   +1 more source

Mate choice in Mus musculus is relative and dependent on the estrous state. [PDF]

PLoS ONE, 2013
Mate choice is a critical behavioral decision process with profound impact on evolution. However, the mechanistic basis of mate choice is poorly understood.
Léa Zinck, Susana Q Lima
doaj   +1 more source

EFIKASI SALEP GETAH JARAK PAGAR 10 % (JATROPHA CURCAS, LINN) DAN SALEP GENTAMISIN 0,1 % TERHADAP PENYEMBUHAN LUKA SAYAT PADA KULIT MENCIT (MUS MUSCULUS) [PDF]

, 2015
EFIKASI SALEP GETAH JARAK PAGAR 10 % (Jatropha curcas, Linn) DAN SALEP GENTAMISIN 0,1 % TERHADAP PENYEMBUHAN LUKA SAYAT PADA KULIT MENCIT (Mus musculus)ABSTRAKPenelitian ini bertujuan mengetahui tingkat efektifitas penyembuhan luka incisi dengan ...
Teuku Suriwidiar
core  

Restriction of Individual Branched‐Chain Amino Acids has Distinct Effects on the Development and Progression of Alzheimer's Disease in 3xTg Mice

Advanced Science, EarlyView.
Protein restriction (PR) slows Alzheimer's disease (AD) in mice, and other benefits of PR are due to decreased branched‐chain amino acids (BCAAs). We show that restricting any BCAA has benefits, with sex‐ and BCAA‐specific impacts on pathology, molecular signaling, and cognition.
Reji Babygirija, Cara L. Green, Michelle M. Sonsalla, Izabelle Marie F. Le, Fan Xiao, Sarah Yandell, Mariah F. Calubag, Michaela E. Trautman, Anna Tobon, Ryan Matoska, Chung‐Yang Yeh, Charles I. Opara, Isaac Grunow, Diana Vertein, Sophia Schlorf, Bailey A. Knopf, Michael J. Rigby, David A. Harris, Mark P. Keller, Alan D. Attie, Luigi Puglielli, Cholsoon Jang, Dudley W. Lamming   +22 more
wiley   +1 more source

Comparative Chromosome Maps of Neotropical Rodents Necromys lasiurus and Thaptomys nigrita (Cricetidae) Established by ZOO-FISH [PDF]

, 2011
This work presents chromosome homology maps between Mus musculus (MMU) and 2 South American rodent species from the Cricetidae group: Necromys lasiurus (NLA, 2n = 34) and Thaptomys nigrita (TNI, 2n = 52), established by ZOO-FISH using mouse chromosome ...
Diaz GB, D’Élia G, D’Élia G, Engelbrecht A, Fagundes V, Ford CE, Gallardo MH, Geise L, Hass I, I. Hass, I.J. Sbalqueiro, Matsubara K, Matsubara K, Musser GG, Nakamura T, R.F. Artoni, Rambau RV, Reig OA, Romanenko SA, S. Müller, Sbalqueiro IJ, Seabright M, Silva MJ, Smith MF, Smith MF, Stanyon R, Ventura K, Ventura K, Yang F   +28 more
core   +1 more source

A Tac1‐Expressing Brainstem Pathway Underlies the Pathogenesis of Trigeminal Neuralgia

Advanced Science, EarlyView.
A critical TG‐Sp5CTac1‐PBNTac1 pathway drives trigeminal neuropathic pain (TNP). Tac1‐expressing parabrachial nucleus (PBNTac1) neurons exhibit heightened responses to innocuous stimuli in TNP, and chemogenetic inhibition of these neurons effectively prevents TNP development.
Liting Sun, Jia‐Jia Wang, Xiang‐Yu Li, Xin‐Yi Lin, Juan Li, Qiu‐Tong Yu, Zi‐Han Wang, Xue‐Ping Gao, Lei Jin, Wei‐Ke Li, Tian‐Lin Cheng, Juan Deng   +11 more
wiley   +1 more source

The Cryptosporidium "mouse" genotype is conserved across geographic areas. [PDF]

, 1999
A 298-bp region of the Cryptosporidium parvum 18S rRNA gene and a 390-bp region of the acetyl coenzyme A synthetase gene were sequenced for a range of Cryptosporidium isolates from wild house mice (Mus domesticus), a bat (Myotus adversus), and cattle ...
Morgan, U.M., Sturdee, A.P., Singleton, G., Gomez, M.S., Gracenea, M., Torres, J., Hamilton, S.G., Woodside, D.P., Thompson, R.C.A.   +8 more
core   +1 more source