Results 51 to 60 of about 126,194 (261)

Enhanced Glycolysis‐Driven Histone H3K18 Lactylation Regulates Epileptogenesis by Modulating the E3 Ubiquitin Ligase COP1

Advanced Science, EarlyView.
Neuronal PKM2‐driven glycolysis generates excess lactate that triggers histone H3K18 lactylation (H3K18la), establishing a pathogenic metabolic‐epigenetic axis in epilepsy. Elevated H3K18la enriches the Cop1 promoter, transcriptionally upregulating the E3 ubiquitin ligase COP1, which subsequently drives proteasomal degradation of GABAARβ2 and impairs ...
Yuan Meng, Yanlin Guo, Liumi Jiang, Jing Luo, Yan Liu, Ziwei Yuan, Pingyang Ke, Ran Duan, Fei Xiao   +8 more
wiley   +1 more source

Mate choice in Mus musculus is relative and dependent on the estrous state. [PDF]

PLoS ONE, 2013
Mate choice is a critical behavioral decision process with profound impact on evolution. However, the mechanistic basis of mate choice is poorly understood.
Léa Zinck, Susana Q Lima
doaj   +1 more source

Palmitic Acid Promotes Antiviral Innate Immunity via ZDHHC20‐Mediated CMPK2 Palmitoylation

Advanced Science, EarlyView.
Metabolites have important functions in innate immune activation and regulation. Wang et al. uncover metabolic regulation of antiviral immunity through CMPK2 palmitoylation, which regulates CMPK2 mitochondrial localization and is promoted by ZDHHC20 but reversed by PPT1, inhibition of which antagonizes viral infection in mice.
Yujia Wang, Zenghui Cui, Yunkai Zhang, Zhiqing Li, Xuetao Cao   +4 more
wiley   +1 more source

Combining Spatial Multi‐Omics Data to Decipher Spatial Domains and Elucidate Cell Heterogeneity Based on Self‐Supervised Graph Learning

Advanced Science, EarlyView.
A self‐supervised multi‐view graph fusion framework integrates spatial multi‐omics, excelling in domain identification and denoising. It reconstructs spatial pseudo‐expression, jointly analyzes multi‐omics data, infers RNA velocity, predicts spatial omics features from single‐cell multi‐omics, and detects spatially dark genes and transcription factors,
Yuejing Lu, Rui Qiao, Ying Li, Junhong Li, Nuoya Yue, Jing Ge, Jiao Wang, Luonan Chen, Peiluan Li   +8 more
wiley   +1 more source

The RNA‐Binding Protein PARN Remodeled 3′ UTR Structure Defines Poly(A)‐Loading Sites to Mediate Immunoglobulin Homeostasis

Advanced Science, EarlyView.
ABSTRACT Class Switch Recombination (CSR) is essential for generating high‐affinity antibody isotypes from IgM during adaptive humoral responses. Despite well‐established roles for various transcription factors, whether CSR is subject to dedicated post‐transcriptional control represents a significant gap in knowledge.
Siyuan Sun, Chen Yang, Xiaoyu Wang, Naijing Hu, Shengyao Zhang, Xinchun Li, Yu Chen, Jianan Zhai, Xiangfeng Tang, Wei Lu, Chenxu Lu, Changchang Cao, Weiru Yu, Wenhao Wu, Xiaonan Nie, Fengchao Wang, Bing Fang, Fazheng Ren, Yixuan Li, Juan Chen   +19 more
wiley   +1 more source

PENGARUH PEMBERIAN PROPOLIS LEBAH TERHADAP GAMBARAN HISTOPATOLOGI HEPAR MENCIT (Mus musculus) BETINA YANG DIPAPAR LOGAM BERAT PB ASETAT [Pb(C2H3O2)2]

Journal of Basic Medical Veterinary, 2020
Lead acetate in the hepatobiliary system may cause peroxidation catalysis of unsaturated fatty acids, reduce nitrogenoxide and increase hydroxyl radical.
Sartika Dewi Rachmani, Erma Safitri, Roesno Darsono, Eka Pramyrtha Hestianah, Hani Plumeriastuti, Kuncoro Puguh Santoso   +5 more
doaj   +1 more source

Absolute protein quantitation of the mouse macrophage Toll-like receptor and chemotaxis pathways

Scientific Data, 2022
Measurement(s) molecules per cell Technology Type(s) nanoflow high-performance liquid chromatography-electrospray ionisation tandem mass spectrometry Sample Characteristic - Organism Mus ...
Nathan P. Manes, Jessica M. Calzola, Pauline R. Kaplan, Iain D. C. Fraser, Ronald N. Germain, Martin Meier-Schellersheim, Aleksandra Nita-Lazar   +6 more
doaj   +1 more source

NFYB Integrates Hormonal Signals into Tissue Allometry by Promoting Protein Biosynthesis

Advanced Science, EarlyView.
In the American cockroach, NFYB acts as a spatiotemporin that translates distinct hormonal cues into tissue‐specific allometry. Juvenile hormone activates NFYB in the early fat body, while 20‐hydroxyecdysone induces it in late wing pads. NFYB then promotes protein biosynthesis via core translational machinery, driving differential growth across the ...
Fangfang Liu, Shiming Zhu, Sishi Xia, Xiaoshuai Zhang, Qin Li, Zhanquan Zeng, Yuqing Liu, Wanyin Liang, Guanyu Zhou, Erxia Du, Suning Liu, Sheng Li   +11 more
wiley   +1 more source

Farklı Omurgalı Türlerinde Bazı Sindirim Kanalı Bölgelerinin Histolojik ve Histokimyasal Yapısı

Süleyman Demirel Üniversitesi Fen-Edebiyat Fakültesi Fen Dergisi, 2014
Özet: Bu çalışmanın amacı, farklı omurgalı türlerinin (Mus musculus, Coturnix coturnix ve Salmo trutta) sindirim kanalının bazı bölgelerinin histolojik yapısı ve mukus hücrelerindeki glikoproteinlerinin histokimyasal tekniklerle belirlemektir. Çalışmada,
Nurgül ŞENOL, Dilek BAYRAM, Özlem YEŞİL   +2 more
doaj  

Mus (Mus) musculus Linnaeus 1758

Published as part of Aidek, Ahmad E., Ibrahim, Amir, Amr, Zuhair, Hutterer, Rainer, Kryštufek, Boris, Serra, Gianluca, Benda, Petr, Shkaky, Yesra, Barbanera, Filippo & Al-Sheikhly, Omar F., 2025, Checklist of Mammals of Syria, pp.
Aidek, Ahmad E., Ibrahim, Amir, Amr, Zuhair, Hutterer, Rainer, Kryštufek, Boris, Serra, Gianluca, Benda, Petr, Shkaky, Yesra, Barbanera, Filippo, Al-Sheikhly, Omar F.   +9 more
openaire   +2 more sources