pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
HISTOLOGICAL STUDY OF THE EFFECT OF THE PARASITE Trichomonas vaginalis ON SOME ORGANS OF THE WHITE SWISS MICE STRAIN BALB/C [PDF]
مجلة جامعة الانبار للعلوم الصرفة, 2013 The study showed that the effect of experimental Trichomonasis caused histological change to some of organs under investigation (prostate and testes and penis) in albino rats .In our study, albino rats were divided into three groups [Group I (Single ...
AYSIR S. MOHAMMAD +2 more
doaj +1 more source
Food Habits of Introduced Rodents in High-Elevation Shrubland of Haleakala National Park, Maui, Hawai'i [PDF]
, 2000 Mus musculus and Rattus rattus are ubiquitous consumers in the high-elevation shrubland of Haleakala National Park. Food habits of these two rodent species were determined from stomach samples obtained by snap-trapping along transects located at four ...
Anderson, Laurel J. +4 more
core
Preparasi Kulit Ekstrak Kulit Buah Manggis untuk Penangkal Diabetes [PDF]
, 2015 Buah manggis yang merupakan buah tropis mengandung antioksidan yang tinggi terutama pada kulitnya. Antioksidan dapat bereaksi dengan radikal bebas dan mencegah kapasitas radikal bebas menimbulkan kerusakan pada sel, jaringan dan atau ...
Darmawansyih, D. (Darmawansyih)
core +2 more sources
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Morphological abnormalities and histopathological lesions of ethyl alcohol During the embryonic development of the Swiss white mouse Mus Musculus [PDF]
مجلة التربية والعلم, 2007 The present study aims at investigating the effects of ethyl alcohol to induce morphological malformation and histological defects during the embryological eye development of the Swiss albino mice Mus musculus at the level of light microscope.
Hani hammodi, Raghad Abbas
doaj +1 more source
PENGARUH PEMBERIAN EKSTRAK ETANOL KULIT BUAH MANGGIS (GARCINIA MAGOSTANA L.) TERHADAP PENURUNAN KADAR GULA DARAH MENCIT (MUS MUSCULUS) YANG DIINDUKSI ALOKSAN [PDF]
, 2015 ABSTRAKDiabetes melitus (DM) adalah suatu keadaan dimana tubuh tidak mampu untuk menghasilkan atau menggunakan insulin. Peningkatan kadar gula dalam darah sangat berisiko untuk menimbulkan komplikasi yang nantinya akan menurunkan kualitas hidup dan ...
INDRA ANAS SULAIMAN
core
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Penurunan Progesterone-Induced Blocking Factor (PIBF) Sebagai Penanda Preeklampsia [PDF]
, 2016 Tujuan: Membandingkan kadar PIBF serum dan berat plasenta pada model preeklampsia.Bahan dan Metode: Penelitian cross sectional yang dilakukan pada 16 Mus musculus bunting normal dan 16 Mus musculus bunting yang diberikan anti Qa-2 untuk membentuk suatu ...
Dachlan, E. G. (Erry) +3 more
core
An HMM-based Comparative Genomic Framework for Detecting Introgression in Eukaryotes [PDF]
, 2013 One outcome of interspecific hybridization and subsequent effects of evolutionary forces is introgression, which is the integration of genetic material from one species into the genome of an individual in another species.
Dai, Jingxuan +5 more
core +2 more sources