To optimise sensory representations based on environmental demands, the activity of cortical neurons is regulated by neuromodulators such as Acetylcholine (ACh).
Wricha Mishra+2 more
doaj +1 more source
Muscarinic acetylcholine receptor M1 mutations causing neurodevelopmental disorder and epilepsy [PDF]
Anna Marcé‐Grau+7 more
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Structure of the m1 Muscarinic Acetylcholine Receptor Gene and Its Promoter [PDF]
S. Pepitoni, Noel J. Buckley, Ian Wood
openalex +1 more source
Single nucleotide polymorphisms of the human M1 muscarinic acetylcholine receptor gene [PDF]
Julie L. Lucas+2 more
openalex +1 more source
Hyperactivity, elevated dopaminergic transmission, and response to amphetamine in M1 muscarinic acetylcholine receptor-deficient mice [PDF]
David J. Gerber+5 more
openalex +1 more source
RGS2 Binds Directly and Selectively to the M1 Muscarinic Acetylcholine Receptor Third Intracellular Loop to Modulate Gq/11α Signaling [PDF]
Leah S. Bernstein+6 more
openalex +1 more source
DYT-TOR1A or DYT1 early-onset generalized dystonia is an inherited movement disorder characterized by sustained muscle contractions causing twisting, repetitive movements, or abnormal postures.
Fumiaki Yokoi+10 more
doaj
Roles of Phosphorylation-dependent and -independent Mechanisms in the Regulation of M1 Muscarinic Acetylcholine Receptors by G Protein-coupled Receptor Kinase 2 in Hippocampal Neurons [PDF]
Jonathon M. Willets+2 more
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A fast genetically encoded fluorescent sensor for faithful in vivo acetylcholine detection in mice, fish, worms and flies [PDF]
Here we design and optimize a genetically encoded fluorescent indicator, iAChSnFR, for the ubiquitous neurotransmitter acetylcholine, based on a bacterial periplasmic binding protein.
Borden, Philip M.+4 more
core
Functional Analysis of Transmembrane Domain 2 of the M1 Muscarinic Acetylcholine Receptor [PDF]
Mark S. Bee, Edward C. Hulme
openalex +1 more source