Results 141 to 150 of about 29,353 (245)

Muscarinic acetylcholine receptor M1 (CHRM1; HM1) [PDF]

Science-Business eXchange, 2009
openaire   +1 more source

Crosstalk between the M1 muscarinic acetylcholine receptor and the endocannabinoid system: A relevance for Alzheimer's disease?

Cellular Signalling, 2020
K. Thompson, A. Tobin
semanticscholar   +1 more source

Muscarinic acetylcholine receptor M1 (CHRM1; HM1) [PDF]

Science-Business eXchange, 2010
openaire   +1 more source

Corrigendum: Striatal dopamine D2-muscarinic acetylcholine M1 receptor-receptor interaction in a model of movement disorders

Frontiers in Pharmacology, 2022
René A. J. Crans, René A. J. Crans, Elise Wouters, Marta Valle-León, Marta Valle-León, Jaume Taura, Jaume Taura, Caio M. Massari, Caio M. Massari, Víctor Fernández-Dueñas, Víctor Fernández-Dueñas, Christophe P. Stove, Francisco Ciruela, Francisco Ciruela   +13 more
doaj   +1 more source

Substituted Benzylspiroindolin-2-one Analogues as Positive Allosteric Modulators of the Muscarinic Acetylcholine Receptor M1.

ACS Medicinal Chemistry Letters, 2013
D. Rotella
semanticscholar   +1 more source

A comprehensive assessment of the cholinergic‐supporting and cognitive‐enhancing effects of Rosa damascena Mill. (Damask rose) essential oil on scopolamine‐induced amnestic rats

Brain and Behavior
Introduction Alzheimer's disease (AD) is a neurodegenerative condition characterized by gradual loss of cognitive abilities (dementia) and is a major public health problem. Here, we aimed at investigating the effects of Rosa damascena essential oil (RDEO)
Kerem Teralı, Dilek Ozbeyli, Duygu Yiğit‐Hanoğlu, Kemal Hüsnü Can Başer, Göksel Şener, Asli Aykac   +5 more
doaj   +1 more source

Dualsteric compounds modulate the signaling pattern of muscarinic M1 acetylcholine receptors

, 2016
G protein-coupled receptors (GPCRs) are cell surface receptors which, upon a conformational change in the receptor protein induced by an extracellular stimulus, can transduce the signal onto intracellular adaptor proteins such as heterotrimeric G proteins [1].
T. Bödefeld, C. Matera, C. Dallanoce, R. Messerer, M. De Amici, U. Holzgrabe, K. Mohr, R. Schrage   +7 more
openaire   +1 more source

Disease-Modifying Effects of M1 Muscarinic Acetylcholine Receptor Activation in an Alzheimer's Disease Mouse Model.

ACS Chemical Neuroscience, 2017
Evan P. Lebois, J. Schroeder, T. Esparza, T. Bridges, C. Lindsley, P. Conn, D. Brody, J. Daniels, I. Allan, Levey   +9 more
semanticscholar   +1 more source

Sequence of the gene encoding the human M1 muscarinic acetylcholine receptor

Nucleic Acids Research, 1987
W J, Allard, I S, Sigal, R A, Dixon
openaire   +3 more sources

Synthesis and Pharmacological Evaluation of Heterocyclic Carboxamides: Positive Allosteric Modulators of the M1 Muscarinic Acetylcholine Receptor with Weak Agonist Activity and Diverse Modulatory Profiles.

Journal of Medicinal Chemistry, 2018
Juliana C. C. Dallagnol, Elham Khajehali, E. T. van der Westhuizen, M. Jörg, C. Valant, A. Gonçalves, B. Capuano, A. Christopoulos, P. Scammells   +8 more
semanticscholar   +1 more source