Results 151 to 160 of about 15,706 (256)

Substituted Benzylspiroindolin-2-one Analogues as Positive Allosteric Modulators of the Muscarinic Acetylcholine Receptor M1

, 2013
David P. Rotella
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Acetylcholine modulates gamma frequency oscillations in the hippocampus by activation of muscarinic M1 receptors [PDF]

, 2017
Ruth Betterton, Lisa M. Broad, Krasimira Tsaneva‐Atanasova, Jack R. Mellor   +3 more
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Dualsteric compounds modulate the signaling pattern of muscarinic M1 acetylcholine receptors

, 2016
G protein-coupled receptors (GPCRs) are cell surface receptors which, upon a conformational change in the receptor protein induced by an extracellular stimulus, can transduce the signal onto intracellular adaptor proteins such as heterotrimeric G proteins [1].
T. Bödefeld, C. Matera, C. Dallanoce, R. Messerer, M. De Amici, U. Holzgrabe, K. Mohr, R. Schrage   +7 more
openaire   +1 more source

Mutagenesis of Nucleophilic Residues near the Orthosteric Binding Pocket of M1 and M2 Muscarinic receptors: Effect on the Binding of Nitrogen Mustard Analogs of Acetylcholine and McN-A-343 [PDF]

, 2010
Hinako Suga, Gregory W. Sawyer, Frederick J. Ehlert   +2 more
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Novel Allosteric Agonists of M1 Muscarinic Acetylcholine Receptors Induce Brain Region-Specific Responses That Correspond with Behavioral Effects in Animal Models [PDF]

, 2012
Gregory J. Digby, Meredith J. Noetzel, Michael Bubser, Thomas J. Utley, Adam G. Walker, Nellie Byun, Evan P. Lebois, Zixiu Xiang, Douglas J. Sheffler, H. P. Cho, Alberta A. Davis, Natali E. Nemirovsky, Sarah E. Mennenga, Bryan W. Camp, Heather A. Bimonte‐Nelson, Juergen Bode, Kimberly Italiano, Ryan D. Morrison, J. Scott Daniels, Colleen M. Niswender, M. Foster Olive, Craig W. Lindsley, Carrie K. Jones, P. Jeffrey Conn   +23 more
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Enhanced arecoline derivatives as muscarinic acetylcholine receptor M1 ligands for potential application as PET radiotracers

, 2020
Marius Ozenil, Katharina Pacher, Theresa Balber, Chrysoula Vraka, Alexander Roller, Wolfgang Hölzer, Helmut Spreitzer, Markus Mitterhauser, Wolfgang Wadsak, Marcus Hacker, Verena Pichler   +10 more
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Changes in Membrane Cholesterol Differentially Influence Preferential and Non-preferential Signaling of the M1 and M3 Muscarinic Acetylcholine Receptors [PDF]

, 2014
Pavel Michal, Esam E. El‐Fakahany, Vladimı́r Doležal   +2 more
openalex   +1 more source

First-in-Human Assessment of ¹¹C-LSN3172176, an M1 Muscarinic Acetylcholine Receptor PET Radiotracer [PDF]

, 2020
Mika Naganawa, Nabeel Nabulsi, Shannan Henry, David Matuskey, Shu-fei Lin, Lawrence J. Slieker, Adam J. Schwarz, Nancy Kant, Cynthia D. Jesudason, Kevin M. Ruley, Antonio Navarro, Hong Gao, Jim Ropchan, David Labaree, Richard E. Carson, Yiyun Huang   +15 more
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M1 muscarinic acetylcholine receptor regulation of endogenous transient receptor potential-canonical, subtype 6 (TRPC6) channels

, 2005
Ju Young Kim
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Acetylcholine muscarinic m1 receptor regulation of cyclic AMP synthesis controls growth factor stimulation of Raf activity.

, 1994
Marijane Russell, S Winitz, Gary L. Johnson   +2 more
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