Results 151 to 160 of about 14,768 (198)

Changes in neurotransmitter-related functional connectivity along the Alzheimer's disease continuum. [PDF]

Brain Commun
Manca R, De Marco M, Soininen H, Ruffini L, Venneri A.   +4 more
europepmc   +1 more source

Acetylcholine muscarinic M2 receptor maintains human Schwann-like adipose-derived phenotype in the absence of differentiating medium. [PDF]

Cell Death Discov
Piovesana R, Faroni A, Tata AM, Reid AJ.
europepmc   +1 more source

Control of cortical slow oscillations and epileptiform discharges with photoswitchable type 1 muscarinic ligands. [PDF]

PNAS Nexus
Sanchez-Sanchez JM, Riefolo F, Barbero-Castillo A, Sortino R, Agnetta L, Manasanch A, Matera C, Bosch M, Forcella M, Decker M, Gorostiza P, Sanchez-Vives MV.   +11 more
europepmc   +1 more source

Inhibitory effect of Zhujing Pill on myopia progression: Mechanistic insights based on metabonomics and network pharmacology. [PDF]

PLoS One
Du Y, Pang M, Chen H, Zhou X, Geng R, Zhang Y, Yang L, Li J, Han Y, Liu J, Zhang R, Bi H, Guo D.   +12 more
europepmc   +1 more source

AiGPro: a multi-tasks model for profiling of GPCRs for agonist and antagonist. [PDF]

J Cheminform
Brahma R, Moon S, Shin JM, Cho KH.
europepmc   +1 more source

Allosteric modulation of laeviganoid-based clerodane diterpenes derivatives in muscarinic acetylcholine M1 receptor against tinnitus: a structure-based virtual screening approach

Jacilene Silva, Matheus Nunes da Rocha, Victor Moreira de Oliveira, Caio Henrique Alexandre Roberto, Francisco Nithael Melo Lúcio, Márcia Machado Marinho, Hélcio Silva dos Santos, Emmanuel Silva Marinho   +7 more
openalex   +1 more source

Alzheimer's disease treatment landscape: current therapies and emerging mechanism-targeted approaches. [PDF]

Neural Regen Res
Yang E, Abd-Elrahman KS.
europepmc   +1 more source

Weight Gain With Advancing Age Is Controlled by the Muscarinic Acetylcholine Receptor M4 in Male Mice.

Endocrinology
Takahashi T, Takase Y, Shiraishi A, Matsubara S, Watanabe T, Kirimoto S, Yamagaki T, Osawa M.   +7 more
europepmc   +1 more source

Discovery of Pre-Clinical Candidate <b>VU6008055</b>/<b>AF98943</b>: A Highly Selective, Orally Bioavailable, and Structurally Distinct Tricyclic M₄ Muscarinic Acetylcholine Receptor Positive Allosteric Modulator (PAM) with Robust In Vivo Efficacy. [PDF]

ACS Chem Neurosci
Engers JL, Bollinger SR, Gregro AR, Capstick RA, Spearing PK, Long MF, Tarr JC, Watson KJ, Chang S, Luscombe VB, Rodriguez AL, Cho HP, Qi A, Niswender CM, Bubser M, Gould RW, Robb WH, Byun N, Gore J, Jones CK, Thomsen MS, Bridges TM, Boutaud O, Conn PJ, Engers DW, Lindsley CW, Temple KJ.   +26 more
europepmc   +1 more source

Long-term muscarinic inhibition increases intrinsic excitability through the upregulation of A-type potassium currents in cortical neurons. [PDF]

Front Cell Dev Biol
Riquelme D, Romo-Toledo P, Leyton P, Moreno C, Leiva-Salcedo E.   +4 more
europepmc   +1 more source