Results 161 to 170 of about 14,768 (198)

Application of Deuterium in an M₁ Positive Allosteric Modulator Back-Up Program: The Discovery of VU6045422. [PDF]

ACS Chem Neurosci
Engers JL, Li J, Han C, Long MF, Gregro AR, Presley CC, Dickerson JW, Peng W, Cho HP, Rodriguez AL, Xiang Z, Boutaud O, O'Carroll C, Dey PM, Burstein ES, Niswender CM, Rook JM, Conn PJ, Engers DW, Lindsley CW.   +19 more
europepmc   +1 more source

Hybrid Allosteric Modulators of M1 Muscarinic Receptors Enhance Acetylcholine Efficacy and Decrease Locomotor Activity and Turning Behaviors in Zebrafish [PDF]

Corey J. Widman, Sestina Ventresca, Jillian Dietrich, Gwendolynne Elmslie, H. Allison Smith, Gina Kaup, Alison Wesley, Madeline Doenecke, Frederick E. Williams, Isaac T. Schiefer, John E. Ellis, William S. Messer   +11 more
openalex   +1 more source

[¹¹C]MK-6884 PET imaging reveals lower M₄ muscarinic acetylcholine receptor availability following cocaine self-administration in male rats. [PDF]

Pharmacol Rep
Gollapelli KK, Krizan I, Bhoopal B, Damuka N, Moriarty C, Miller M, Sai KKS, Gould RW.   +7 more
europepmc   +1 more source

A Brief Overview of Cholinergic and Phosphodiesterase-5 Inhibitors in Diabetic Bladder Dysfunction. [PDF]

Int J Mol Sci
Kallinikas G, Haronis G, Kallinika E, Kozyrakis D, Rodinos E, Filios A, Filios P, Mityliniou D, Safioleas K, Zarkadas A, Bozios D, Karmogiannis A, Konstantinopoulos V, Konomi AM, Ektesabi AM, Tsoporis JN.   +15 more
europepmc   +1 more source

Discovery of VU0467319: an M₁ Positive Allosteric Modulator Candidate That Advanced into Clinical Trials. [PDF]

ACS Chem Neurosci
Poslunsey MS, Wood MR, Han C, Stauffer SR, Panarese JD, Melancon BJ, Engers JL, Dickerson JW, Peng W, Noetzel MJ, Cho HP, Rodriguez AL, Hopkins CR, Morrison R, Crouch RD, Bridges TM, Blobaum AL, Boutaud O, Daniels JS, Kates MJ, Castelhano A, Rook JM, Niswender CM, Jones CK, Conn PJ, Lindsley CW.   +25 more
europepmc   +1 more source

The Role of α7-Nicotinic Acetylcholine Receptors in the Pathophysiology and Treatment of Parkinson's Disease. [PDF]

Int J Mol Sci
ElNebrisi E, Lozon Y, Oz M.
europepmc   +1 more source

Molecular Adaptations of BDNF/NT-4 Neurotrophic and Muscarinic Pathways in Ageing Neuromuscular Synapses. [PDF]

Int J Mol Sci
Balanyà-Segura M, Polishchuk A, Just-Borràs L, Cilleros-Mañé V, Silvera C, Ardévol A, Tomàs M, Lanuza MA, Hurtado E, Tomàs J.   +9 more
europepmc   +1 more source

Visual hallucinations in Parkinson's disease: spotlight on central cholinergic dysfunction. [PDF]

Brain
Ignatavicius A, Matar E, Lewis SJG.
europepmc   +1 more source

BDNF/TrkB signalling, in cooperation with muscarinic signalling, retrogradely regulates PKA pathway to phosphorylate SNAP-25 and Synapsin-1 at the neuromuscular junction. [PDF]

Cell Commun Signal
Polishchuk A, Cilleros-Mañé V, Balanyà-Segura M, Just-Borràs L, Forniés-Mariné A, Silvera-Simón C, Tomàs M, Jami El Hirchi M, Hurtado E, Tomàs J, Lanuza MA.   +10 more
europepmc   +1 more source