Results 211 to 220 of about 29,153 (282)

Evaluation of the Alterations in Central Cholinergic Neurotransmission in Aging and Amyloid Precursor Protein Knock-In Mice. [PDF]

J Neurochem
Nagai-Arakawa I, Muramatsu I, Uwada J, Tsuda Y, Tokunaga A, Irie A, Maeda H, Madokoro Y, Sato T, Uchida Y, Saito T, Saido TC, Sada K, Masuoka T, Matsukawa N.   +14 more
europepmc   +1 more source

Schizophrenia: Genetics, neurological mechanisms, and therapeutic approaches. [PDF]

Neural Regen Res
Lim DXE, Yeo SY, Chia ZYA, Fernandis AZ, Lee J, Chua JJE.   +5 more
europepmc   +1 more source

Cryo-EM reveals an extrahelical allosteric binding site at the M₅ mAChR. [PDF]

Nat Commun
Burger WAC, Mobbs JI, Rana B, Wang J, Joshi K, Gentry PR, Yeasmin M, Venugopal H, Bender AM, Lindsley CW, Miao Y, Christopoulos A, Valant C, Thal DM.   +13 more
europepmc   +1 more source

Impaired neuromodulator crosstalk delays arousal-dependent astroglia Ca²⁺ activation in mouse models of Alzheimer's disease. [PDF]

iScience
Heo EY, Salinas-Birt A, Ye L, Sajadi S, Sarker MK, Yang Y, Paukert M.   +6 more
europepmc   +1 more source

Correction: Toward an understanding of the structural basis of allostery in muscarinic acetylcholine receptors. [PDF]

J Gen Physiol
Burger WAC, Sexton PM, Christopoulos A, Thal DM.   +3 more
europepmc   +1 more source

Safety, tolerability, pharmacokinetic and pharmacodynamic effects of the muscarinic M₁ positive allosteric modulator VU0467319 for Alzheimer's disease: a single ascending-dose study in healthy participants. [PDF]

Alzheimers Res Ther
Conley AC, Key AP, Blackford JU, Russell JK, Albert KM, Gong X, Bubser M, Rook JM, Conn PJ, Lindsley CW, Jones CK, Newhouse PA.   +11 more
europepmc   +1 more source

Evidence for M2 Muscarinic Receptor Antagonist Delay of Myopia Development Through Activation of Kir3.4 Channel in the Retina of Guinea Pigs. [PDF]

Invest Ophthalmol Vis Sci
Zhou H, Zhou G, Yang Q, Niu J, Wang R, Liu H, Hou S, Bi H, Liao X.   +8 more
europepmc   +1 more source