Results 71 to 80 of about 3,324 (136)

Structure of the m1 Muscarinic Acetylcholine Receptor Gene and Its Promoter [PDF]

, 1997
S. Pepitoni, Noel J. Buckley, Ian Wood
openalex   +1 more source

Activation of M1 cholinergic receptors in mouse somatosensory cortex enhances information processing and detection behaviour

Communications Biology
To optimise sensory representations based on environmental demands, the activity of cortical neurons is regulated by neuromodulators such as Acetylcholine (ACh).
Wricha Mishra, Ehsan Kheradpezhouh, Ehsan Arabzadeh   +2 more
doaj   +1 more source

Muscarinic acetylcholine receptor M1 mutations causing neurodevelopmental disorder and epilepsy [PDF]

, 2021
Anna Marcé‐Grau, Xabier Elorza‐Vidal, Carla Pérez‐Rius, Anna Ruiz, Júlia Sala‐Coromina, Elisabet Gabau, Raúl Estévez, Alfons Macaya   +7 more
openalex   +1 more source

The potential of muscarinic M1 and M4 receptor activators for the treatment of cognitive impairment associated with schizophrenia

Frontiers in Psychiatry
Cognitive impairment is a core symptom of schizophrenia and a major determinant of poor long-term functional outcomes. Despite considerable efforts, we do not yet have any approved pharmacological treatments for cognitive impairment associated with ...
Samantha E. Yohn, Phillip D. Harvey, Stephen K. Brannan, William P. Horan, William P. Horan   +4 more
doaj   +1 more source

Single nucleotide polymorphisms of the human M1 muscarinic acetylcholine receptor gene [PDF]

, 2001
Julie L. Lucas, Wolfgang Sadée, Joseph DeYoung   +2 more
openalex   +1 more source

Hyperactivity, elevated dopaminergic transmission, and response to amphetamine in M1 muscarinic acetylcholine receptor-deficient mice [PDF]

, 2001
David J. Gerber, Tatyana D. Sotnikova, Raul R. Gainetdinov, Shu Ying Huang, Marc G. Caron, Susumu Tonegawa   +5 more
openalex   +1 more source

RGS2 Binds Directly and Selectively to the M1 Muscarinic Acetylcholine Receptor Third Intracellular Loop to Modulate Gq/11α Signaling [PDF]

, 2004
Leah S. Bernstein, Suneela Ramineni, Chris Hague, Wendy Cladman, Peter Chidiac, Allan I. Levey, John R. Hepler   +6 more
openalex   +1 more source

Reversal of motor-skill transfer impairment by trihexyphenidyl and reduction of dorsolateral striatal cholinergic interneurons in Dyt1 ΔGAG knock-in mice

IBRO Neuroscience Reports, 2021
DYT-TOR1A or DYT1 early-onset generalized dystonia is an inherited movement disorder characterized by sustained muscle contractions causing twisting, repetitive movements, or abnormal postures.
Fumiaki Yokoi, Mai Tu Dang, Lin Zhang, Kelly M. Dexter, Iakov Efimenko, Shiv Krishnaswamy, Matthew Villanueva, Carly I. Misztal, Malinda Gerard, Patrick Lynch, Yuqing Li   +10 more
doaj  

Roles of Phosphorylation-dependent and -independent Mechanisms in the Regulation of M1 Muscarinic Acetylcholine Receptors by G Protein-coupled Receptor Kinase 2 in Hippocampal Neurons [PDF]

, 2005
Jonathon M. Willets, Stefan R. Nahorski, R. A. John Challiss   +2 more
openalex   +1 more source

Impaired neurovascular coupling in the APPxPS1 mouse model of Alzheimer’s disease [PDF]

arXiv, 2019
The tight coupling between neuronal activity and the local increase of blood flow termed neurovascular coupling is essential for normal brain function. This mechanism of regulation is compromised in Alzheimer's Disease (AD). In order to determine whether a purely vascular dysfunction or a neuronal alteration of blood vessels diameter control could be ...
arxiv