Results 121 to 130 of about 13,057 (254)

M3 muscarinic acetylcholine receptors regulate epithelial–mesenchymal transition, perineural invasion, and migration/metastasis in cholangiocarcinoma through the AKT pathway

Cancer Cell International, 2018
Background Cholangiocarcinoma is a highly malignant tumor type that is not sensitive to radiotherapy or chemotherapy due to aggressive perineural invasion and metastasis.
Yujie Feng, Xiao Hu, Guangwei Liu, Lianfang Lu, Wei Zhao, Fangzhen Shen, Kai Ma, Chuandong Sun, Chengzhan Zhu, Bingyuan Zhang   +9 more
doaj   +1 more source

Chronic exposure to the anti-M3 muscarinic acetylcholine receptor autoantibody in pemphigus vulgaris contributes to disease pathophysiology [PDF]

, 2022
Alex I. Chernyavsky, Mykhailo M. Khylynskyi, Krupa G. Patel, Sergei A. Grando   +3 more
openalex   +1 more source

Expression and function of G-protein-coupled receptorsin the male reproductive tract [PDF]

, 2009
This review focuses on the expression and function of muscarinic acetylcholine receptors (mAChRs), α1-adrenoceptors and relaxin receptors in the male reproductive tract.
ABOUD R, ALONSO-LLAMAZARES A, ANAND-IVELL RJ, ANDERSON MB, BAN Y, BATHGATE RA, BATHGATE RA, BERNARD V, BERNARD V, BHATHAL PS, BIRDSALL NJ, BISHOP MJ, BLANCO M, BOGIC L, BORGES MOR, BRADDON SA, BRODDE OE, BURAZIN TC, BURT RP, BURT RP, CAMPOS M, Catarina S. Porto, CAULFIELD MP, CHALOTHORN D, CHAN HC, CHANG DJ, CHATURAPANICH G, CHEAH SH, CHEN S, CHEN S, COGÉ F ET AL, DA SILVA MC, DALY CJ, DANIELS DV, DAVENPORT CW, DEBRUYNE FM, DENG XF, DIVIANI D, DOCHERTY JR, DOCHERTY JR, DOGGRELL SA, DU JY, EGLEN RM, EGLEN RM, EHRÉN I, EISENHOFER G, ERRASTI AE, ESBENSHADE TA, ESSIG M, FENG S, FEVOLD HL, FILONZI M, FORD APDW, FORD APDW, FORRAY C, FUKASAWA R, GAO B, GAO B, GOBEIL F JR, GONZÁLEZ-ESPINOSA C, GRAHAM RM, GRIMM U, GUNNERSEN JM, GUNNERSEN JM, HAAG C, HAGUE C, HAGUE C, HALLS ML, HALLS ML, HALLS ML, HAMAMURA M, HANFT G, HANSELL DJ, HAUSER F, HAWRYLYSHYN KA, HEIN P, HIB J, HIB J, HIEBLE JP, HIEBLE JP, HIRASAWA A, HIRASAWA A, HIRASAWA A, HISAW FL, HOMMA Y, HORIE K, HROMETZ SL, HSU SY, HSU SY, HU K, HULEIHEL M, HULME EC, HWA J, HWA J, HWA J, II M, IRAM S, IVELL R, IVELL R, JACKSON VM, JEYABALAN A, JEYABALAN A, JIANG X, JOCKENHOVEL F, JUDSON DG, JURKIEWICZ NH, KAMAT AA, KARKANIAS GB, KERN A, KIM JK, KINGHORN EM, KOHSAKA T, KONDO S, KRAJNC-FRANKEN MA, KUBO T, KUDO M, LACEY JP, LANGER S, LANZAFAME AA, LAU WA, LAZ TM, LEEB-LUNDBERG LM, LEFKOWITZ RJ, LEFKOWITZ RJ, LEFKOWITZ RJ, LENHART JA, LEPOR H, LEUNG AYH, LIU C, LOCKWOOD DH, LONGHURST PA, LOPEZ-GIMENEZ JF, LUCAS TFG, LUCAS TFG, LUTHIN GR, MACDONALD A, MACKENZIE JF, MACKINNON AC, MALLARD NJ, MANNI L, MANNI L, Maria Christina W. Avellar, Maria Fatima M. Lázari, MARKUS RP, MARÓSTICA E, MARÓSTICA E, MCCUNE DF, MCCUNE SK, MENDES FR, MICHELOTTI GA, MICHELOTTI GA, MIRANDA HF, MIRANDA HF, MIRANDA HF, MOOKERJEE I, MORIYAMA N, MORROW AL, MURAMATSU I, MURRAY KT, NADELHAFT I, NAKAOKA H, NASU K, NASU K, NEWINGER J, NISHIS, NOTHACKER HP, OBARA K, PAPATSORIS AG, PATRÃO MT, PEDRETTI A, PEREZ DM, PETITTI N, PIASCIK MT, PIASCIK MT, PIASCIK MT, PONTARI MA, PORTER JE, PRENZEL N, PRICE DT, PRICE DT, PRICE RR, PUPO AS, PUPO AS, QUEIRÓZ DB, QUEIRÓZ DBC, QUESADA A, RAMARAO CS, RAMSAY D, RATNASOORIYA WD, RATNASOORIYA WD, RAYFORD W, RICKER DD, ROEHRBORN CG, ROKOSH DG, ROKOSH DG, RUDNER XL, RUFFOLO RR JR, RUGGIERI MR, SALAMANCA AE, SALLÉS J, SAMUEL CS, SAMUEL CS, SAMUEL CS, SANBE A, SANBORN BM, SAROSI P, SATO T, SAUSSY DL JR, SAWUTZ DG, SCARPARO AC, SCHWINN DA, SCHWINN DA, SCOFIELD MA, SCOTT DJ, SCOTT DJ, SHANNON HE, SHAPIRO E, SHEN H, SHERWOOD OD, SHIMA S, SHINOURA H, SILVA MA, SIU ER, SKINNER MK, SOKOL RZ, STEINETZ BG, SUDO S, SUGAWARA T, SUZUKI F, TAYEBATI SK, TENG CM, TENSEN CP, TESTA R, THEBAULT S, THEROUX TL, TOEWS ML, UBERTI MA, UBERTI MA, VAN DIJK MM, VAN KOPPEN CJ, VARMA DR, VENTURA S, VICENTIC A, VIVAS NM, VÁZQUEZ-PRADO J, WALDEN PD, WALKER WH, WANG JM, WANG X ET AL, WAUGH DJ, WESS J, WIER WG, XIAO L, XU Z, YAN HH, YANG M, YANG-FENG TL, YANG-FENG TL, YASUOKA A, YAZAWA H, YAZAWA H, YKI-JARVINEN H, YOSHINAGA T, ZHAO L, ZHONG H, ZHONG H, ZIMMERMANN S, ZUSCIK MJ   +267 more
core   +3 more sources

Associations of genetic variations in the M3 receptor with salt sensitivity, longitudinal changes in blood pressure and the incidence of hypertension in Chinese adults

The Journal of Clinical Hypertension
Recent studies have reported the role of the M3 muscarinic acetylcholine receptor (M3R), a member of the G‐protein coupled receptor superfamily, encoded by the CHRM3 gene, in cardiac function and the regulation of blood pressure (BP).
Xi Zhang, Shi Yao, Peng Bao, Mingfei Du, Guilin Hu, Chao Chu, Dan Wang, Chen Chen, Qiong Ma, Hao Jia, Yue Sun, Yu Yan, Yueyuan Liao, Zejiaxin Niu, Ziyue Man, Lan Wang, Weihua Gao, Hao Li, Jie Zhang, Wenjing Luo, Xin Wang, Yang Wang, Jianjun Mu   +22 more
doaj   +1 more source

Deepening insights into cholinergic agents for intraocular pressure reduction: systems genetics, molecular modeling, and in vivo perspectives

Frontiers in Molecular Biosciences
Parasympathetic activation in the anterior eye segment regulates various physiological functions. This process, mediated by muscarinic acetylcholine receptors, also impacts intraocular pressure (IOP) through the trabecular meshwork. While FDA-approved M3
Minjae J. Kim, Mohamed M. Ibrahim, Mohamed M. Ibrahim, Monica M. Jablonski, Monica M. Jablonski   +4 more
doaj   +1 more source

Muscarinic Agonist-Mediated Heterologous Desensitization in Isolated Ileum Requires Activation of Both Muscarinic M2 and M3 Receptors [PDF]

, 2004
We investigated the subtypes of the muscarinic receptor mediating short-term heterologous desensitization in the isolated ileum. Treatment of the ileum from C57BL/6 mice with acetylcholine (30 μM) for 20 min caused a subsequent decrease in contractile ...
Ansari, Khurram Z., Ehlert, Frederick J., Griffin, Michael T., Manabe, Toshiya, Matsui, Minoru, Shehnaz, Darakhshanda, Taketo, Makoto M.   +6 more
core   +2 more sources

P2Y2 Purinergic and M3 Muscarinic Acetylcholine Receptors Activate Different Phospholipase C-β Isoforms That Are Uniquely Susceptible to Protein Kinase C-dependent Phosphorylation and Inactivation [PDF]

, 2000
Derek Strassheim, Carol L. Williams
openalex   +1 more source

Contrary effects of the gut metabolites deoxycholate and butyrate on the acetylcholine-evoked calcium response in an enteroendocrine cell model

Endocrine and Metabolic Science
The interaction of nutrients and bacterial-derived products and their enteroendocrine effects are still enigmatic. We used the human enteroendocrine tumour cell line P-STS isolated from the terminal ileum as cellular sentinel.
Beatrix Pfanzagl, Erika Jensen-Jarolim
doaj  

Effects of Nerve Growth Factor shRNA Inhibition on Asthma Phenotypes in a Mouse Model of Asthma

Iranian Journal of Allergy, Asthma and Immunology, 2018
Nerve growth factor (NGF) plays an important role in airway hyper-responsiveness (AHR). In this study, we aimed at investigating the effect of NGF inhibition on AHR and other asthma phenotypes in a mouse model of asthma.
Jinhong Wu, Bing Chen, Wenxian Li, Yanan Xiao   +3 more
doaj  

The Lower Urinary Tract Science Group Abstracts—ICI‐RS 2024

Neurourology and Urodynamics, Volume 44, Issue 3, Page 691-697, March 2025.
Christopher H. Fry, Andrew Gammie, Bahareh Vahabi, Faezeh A. Hassani, Karen D. McCloskey, Mathijs M. de Rijk, Pradeep Tyagi, Hikaru Hashitani, Michael Winder, Patrik Aronsson, Basu Chakrabarty   +10 more
wiley   +1 more source