Expression of M3 muscarinic acetylcholine receptors in gastric cancer [PDF]
Romanian Journal of Morphology and Embryology, 2022 Gastric cancer represents a real public health problem as far as incidence, aggressiveness and unfavorable prognosis are concerned. The autonomous nervous system might be one of the major factors involved in the onset, progression, and metastasis, both sympathetically and parasympathetically.
Alina Maria Mehedințeanu +9 more
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Muscarinic Acetylcholine Receptor M3 Expression and Survival in Human Colorectal Carcinoma-An Unexpected Correlation to Guide Future Treatment? [PDF]
Int J Mol Sci, 2023 Lobbes LA +7 more
europepmc +3 more sources
Muscarinic acetylcholine receptor M3 (CHRM3; HM3) [PDF]
Science-Business eXchange, 2009 openalex +3 more sources
Acetylcholine-treated murine dendritic cells promote inflammatory lung injury. [PDF]
PLoS ONE, 2019 In recent years a non-neuronal cholinergic system has been described in immune cells, which is often usually activated during the course of inflammatory processes. To date, it is known that Acetylcholine (ACh), a neurotransmitter extensively expressed in
Soledad Gori +8 more
doaj +2 more sources
The M3 Muscarinic Acetylcholine Receptor Promotes Epidermal Differentiation
Journal of Investigative Dermatology, 2022 The M3 muscarinic acetylcholine receptor is predominantly expressed in the basal epidermal layer where it mediates the effects of the autocrine/paracrine cytotransmitter acetylcholine. Patients with the autoimmune blistering disease pemphigus develop autoantibodies to M3 muscarinic acetylcholine receptor and show alterations in keratinocyte adhesion ...
Junyan Duan +6 more
semanticscholar +5 more sources
Teaching an Old Drug New Tricks: Agonism, Antagonism, and Biased Signaling of Pilocarpine through M3 Muscarinic Acetylcholine Receptor [PDF]
Molecular Pharmacology, 2017 Alexey Pronin +2 more
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Effect of M3 muscarinic acetylcholine receptor deficiency on collagen antibody-induced arthritis [PDF]
Arthritis Research & Therapy, 2016 BackgroundThere is increasing evidence that the non-neuronal cholinergic system might be of importance for the pathology of rheumatoid arthritis. The role of M3 muscarinic acetylcholine receptor (M3R) in this regard has, however, not been investigated to
J. Beckmann +4 more
semanticscholar +7 more sources
The M3 Muscarinic Acetylcholine Receptor Can Signal through Multiple G Protein Families
Molecular PharmacologyThe M3 muscarinic acetylcholine receptor (M3R) is a G protein–coupled receptor (GPCR) that regulates important physiologic processes, including vascular tone, bronchoconstriction, and insulin secretion.
Jeffrey S. Smith +5 more
semanticscholar +3 more sources
Ischemia Impairs the Association Between Connexin 43 and M3 Subtype of Acetylcholine Muscarinic Receptor (M3-mAChR) in Ventricular Myocytes [PDF]
Cellular Physiology and Biochemistry, 2006 Peng Yue +11 more
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Mechanisms of Pilocarpine-Induced Nitric Oxide and Prostaglandin Production in Porcine Ciliary Muscle. [PDF]
FASEB BioadvPilocarpine activates M1 and M3 muscarinic receptors in porcine ciliary muscle, engaging calcium‐dependent phospholipase C (PLC), nitric oxide synthase (NOS), and cyclooxygenase (COX) pathways that increase prostaglandin E2 (PGE2) synthesis. Beyond nitric oxide (NO) modulation, PGE2 emerges as a key mediator linking muscarinic signaling to ciliary ...
Benozzi G +3 more
europepmc +2 more sources