Results 11 to 20 of about 13,541 (253)
The Role of Muscarinic Acetylcholine Receptor M3 in Cardiovascular Diseases. [PDF]
Int J Mol SciThe muscarinic acetylcholine receptor M3 (M3-mAChR) is involved in various physiological and pathological processes. Owing to specific cardioprotective effects, M3-mAChR is an ideal diagnostic and therapeutic biomarker for cardiovascular diseases (CVDs).
Liu X, Yu Y, Zhang H, Zhang M, Liu Y.
europepmc +5 more sources
Structure and dynamics of the M3 muscarinic acetylcholine receptor [PDF]
Nature, 2012 Acetylcholine, the first neurotransmitter to be identified, exerts many of its physiological actions via activation of a family of G-protein-coupled receptors (GPCRs) known as muscarinic acetylcholine receptors (mAChRs). Although the five mAChR subtypes (M1-M5) share a high degree of sequence homology, they show pronounced differences in G-protein ...
Kruse, Andrew C. +13 more
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Beneficial metabolic effects of M3 muscarinic acetylcholine receptor deficiency [PDF]
Cell Metabolism, 2006 Most animal models of obesity and hyperinsulinemia are associated with increased vagal cholinergic activity. The M3 muscarinic acetylcholine receptor subtype is widely expressed in the brain and peripheral tissues and plays a key role in mediating the physiological effects of vagal activation.
Gautam, Dinesh +7 more
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Allosteric interactions at the M3 muscarinic acetylcholine receptor [PDF]
, 2008 The extracellular loops of muscarinic acetylcholine receptors are predicted to play a role in the binding and regulation of allosteric modulators. Furthermore, the sequence of the five subtypes of muscarinic receptors shows a large degree of diversity in this region.
Laura Iarriccio Silva
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The M3 Muscarinic Acetylcholine Receptor Promotes Epidermal Differentiation [PDF]
Journal of Investigative Dermatology, 2022 The M3 muscarinic acetylcholine receptor is predominantly expressed in the basal epidermal layer where it mediates the effects of the autocrine/paracrine cytotransmitter acetylcholine. Patients with the autoimmune blistering disease pemphigus develop autoantibodies to M3 muscarinic acetylcholine receptor and show alterations in keratinocyte adhesion ...
Junyan Duan +6 more
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Molecular Cloning of m3 Muscarinic Acetylcholine Receptor in Rat Iris.
Journal of Smooth Muscle Research, 1998 Muscarinic receptor subtypes that involved in cholinergic responses in rat iris were identified by reverse transcription-polymerase chain reaction (RT-PCR) analysis. mRNAs encoding m2, m3, and m4 subtypes were abundantly expressed in iris, whereas m1 and m5 subtypes were not detected.
Michino Furuta +3 more
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Adrenergic receptor β2 (ADRB2); muscarinic acetylcholine receptor M3 (CHRM3; HM3) [PDF]
Science-Business eXchange, 2011 openalex +2 more sources
Muscarinic acetylcholine receptor M3 (CHRM3; HM3) [PDF]
Science-Business eXchange, 2009 openalex +3 more sources
Selective expression of muscarinic acetylcholine receptor subtype M3 by mouse type III taste bud cells [PDF]
, 2016 Yusuke Mori +3 more
core +3 more sources