Results 161 to 170 of about 18,227 (256)

Discovery of Pre-Clinical Candidate <b>VU6008055</b>/<b>AF98943</b>: A Highly Selective, Orally Bioavailable, and Structurally Distinct Tricyclic M₄ Muscarinic Acetylcholine Receptor Positive Allosteric Modulator (PAM) with Robust In Vivo Efficacy. [PDF]

ACS Chem Neurosci
Engers JL, Bollinger SR, Gregro AR, Capstick RA, Spearing PK, Long MF, Tarr JC, Watson KJ, Chang S, Luscombe VB, Rodriguez AL, Cho HP, Qi A, Niswender CM, Bubser M, Gould RW, Robb WH, Byun N, Gore J, Jones CK, Thomsen MS, Bridges TM, Boutaud O, Conn PJ, Engers DW, Lindsley CW, Temple KJ.   +26 more
europepmc   +1 more source

Design, Synthesis, and Evaluation of a New Fluorescent Ligand for the M₂ Muscarinic Acetylcholine Receptor. [PDF]

ACS Med Chem Lett
Szabó R, Szepesi Kovács D, Kiss DJ, Yazdi ZN, Tóth AD, Brea J, Loza MI, Meszéna D, Wittner L, Ulbert I, Volk B, Hunyady L, Keserű GM.   +12 more
europepmc   +1 more source

Investigation of the presence and antinociceptive function of muscarinic acetylcholine receptors in the African naked mole-rat () [PDF]

core   +1 more source

Promoter Region of the Rat m4 Muscarinic Acetylcholine Receptor Gene Contains a Cell Type-specific Silencer Element [PDF]

, 1996
Michihiro Mieda, Tatsuya Haga, David Saffen   +2 more
openalex   +1 more source

Is muscarinic receptor agonist effective and tolerant for schizophrenia? [PDF]

BMC Psychiatry
Guo X, Deng R, Lai J, Hu S.
europepmc   +1 more source

The Role of Membrane Proximal Threonine Residues Conserved among Guanine‐Nucleotide‐Binding‐Protein‐Coupled Receptors in Internalization of the m4 Muscarinic Acetylcholine Receptor [PDF]

, 1995
Chris J. van Koppen, W. Lenz, José Pedro L. Nunes, Chunyi Zhang, Martina Schmidt, Karl H. Jakobs   +5 more
openalex   +1 more source

Co-stimulation of muscarinic M1 and M4 acetylcholine receptors prevents later cocaine reinforcement in male and female mice, but not place-conditioning

Abhishek Shankar Balakrishnan, Lærke Bornø Engelhardt Johansen, Craig W. Lindsley, P. Jeffrey Conn, Morgane Thomsen   +4 more
openalex   +1 more source

A sex-specific effect of M₄ muscarinic cholinergic autoreceptor deletion on locomotor stimulation by cocaine and scopolamine. [PDF]

Front Mol Neurosci
Berezovskaia A, Thomsen M, Fink-Jensen A, Wörtwein G.   +3 more
europepmc   +1 more source

An allosteric enhancer of M4 muscarinic acetylcholine receptor function inhibits behavioral and neurochemical effects of cocaine

, 2012
Ditte Dencker, Pia Weikop, G. Sørensen, David P.D. Woldbye, Gitta Wörtwein, Jürgen Wess, Anders Fink‐Jensen   +6 more
openalex   +2 more sources

Evidence for M2 Muscarinic Receptor Antagonist Delay of Myopia Development Through Activation of Kir3.4 Channel in the Retina of Guinea Pigs. [PDF]

Invest Ophthalmol Vis Sci
Zhou H, Zhou G, Yang Q, Niu J, Wang R, Liu H, Hou S, Bi H, Liao X.   +8 more
europepmc   +1 more source