Results 111 to 120 of about 2,979 (198)

Data regarding M1 muscarinic receptor-mediated modulation of hepatic catalase activity in response to oxidative stress

Data in Brief, 2016
We recently demonstrated the role of M1 muscarinic receptors (M1R) in modulating oxidative stress in liver and hepatocytes (Urrunaga et al., 2015) [1]. Here we provide data regarding the effect of a novel M1R agonist, VU0357017 (Lebois et al., 2010) [2],
Ravirajsinh N. Jadeja, Nathalie H. Urrunaga, Daniel Ahmad, Sandeep Khurana   +3 more
doaj  

Vitamin D deficiency induces erectile dysfunction: Role of superoxide and Slpi

British Journal of Pharmacology, EarlyView.
Background and Purpose Epidemiological studies suggest a relationship between vitamin D deficiency and erectile dysfunction (ED). We hypothesized that vitamin D deficiency or vitamin D receptor (VDR) knockout causes ED and analysed the underlying molecular mechanisms.
Miguel A. Olivencia, Belén Climent, Bianca Barreira, Daniel Morales‐Cano, Ana Sánchez, Argentina Fernández, Borja García‐Gómez, Javier Romero‐Otero, Claudia Rodríguez, Laura Moreno, Dolores Prieto, María Jesús Larriba, Angel Cogolludo, Javier Angulo, Francisco Perez‐Vizcaino   +14 more
wiley   +1 more source

Dimerisation of the VIP receptor VIPR2 is essential to its binding VIP and Gαi proteins, and to its functions in breast cancer cells

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Several G protein‐coupled receptors (GPCRs) are known to homodimerise. Dimeric GPCRs may have different properties from their monomers, but the molecular basis and functional significance of GPCR dimerisation remain largely unknown.
Satoshi Asano, Kairi Ozasa, Teru Uehara, Rei Yokoyama, Takanobu Nakazawa, Souichi Yanamoto, Yukio Ago   +6 more
wiley   +1 more source

A Random Forest-based Prediction Model for Turning Points in Antagonistic Event-Group Competitions [PDF]

arXiv
At present, most of the prediction studies related to antagonistic event-group competitions focus on the prediction of competition results, and less on the prediction of the competition process, which can not provide real-time feedback of the athletes' state information in the actual competition, and thus can not analyze the changes of the competition ...
arxiv  

Characterization of the muscarinic receptor subtype(s) mediating contraction of the guinea‐pig lung strip and inhibition of acetylcholine release in the guinea‐pig trachea with the selective muscarinic receptor antagonist tripitramine [PDF]

, 1997
Ad F. Roffel, Joost H. Davids, Carolina R.S. Elzinga, Doris Wolf, Johan Zaagsma, H. Kilbinger   +5 more
openalex   +1 more source

Dupilumab Efficacy and Safety in Patients With Persistent Asthma: Asia–Pacific Region

Clinical &Experimental Allergy, EarlyView.
Asthma prevalence is increasing in the Asia–Pacific region, and this population is frequently underrepresented in phase 3 clinical studies. We demonstrate Dupilumab's efficacy and safety among patients with uncontrolled moderate‐to‐severe type 2 asthma.
Qingling Zhang, Nanshan Zhong, Sahajal Dhooria, Xiuhua Fu, Haohui Fang, Jie Lin, Shuyang Zhu, Elizabeth Laws, Yi Wang, Vivian Li, Chih‐Chi Hu, Jennifer Maloney, Raolat M. Abdulai, Lacey B. Robinson   +13 more
wiley   +1 more source

Patient considerations in the treatment of COPD: focus on the new combination inhaler umeclidinium/vilanterol

Patient Preference and Adherence, 2015
Timothy E Albertson,1–3 Richart Harper,1,2 Susan Murin,1,2 Christian Sandrock1 1Department of Internal Medicine, Division of Pulmonary, Critical Care and Sleep Medicine, School of Medicine, University of California, Davis, Sacramento, CA, USA;
Albertson TE, Harper R, Murin S, Sandrock C   +3 more
doaj  

Stretchable Electrohydraulic Artificial Muscle for Full Motion Ranges in Musculoskeletal Antagonistic Joints [PDF]

arXiv
Artificial muscles play a crucial role in musculoskeletal robotics and prosthetics to approximate the force-generating functionality of biological muscle. However, current artificial muscle systems are typically limited to either contraction or extension, not both.
arxiv  

Isomerization of the muscarinic receptor . antagonist complex.

, 1979
Jaak Järv, Britta Hedlund, Tamás Bartfai   +2 more
openalex   +1 more source

Molecular probes for muscarinic receptors: Functionalized congeners of selective muscarinic antagonists [PDF]

, 1995
Kenneth A. Jacobson, Bilha Fischer, A. Michiel van Rhee   +2 more
openalex   +1 more source