Results 141 to 150 of about 2,979 (198)

Differential control of human cardiac β-adrenergic and muscarinic receptors by chronic β-adrenoceptor antagonist treatment

, 1990
Shigeru Motomura, Otto‐Erich Brodde
openalex   +1 more source

M3 Muscarinic Receptor Antagonists Inhibit Small Cell Lung Carcinoma Growth and Mitogen-Activated Protein Kinase Phosphorylation Induced by Acetylcholine Secretion [PDF]

, 2007
Pingfang Song, Harmanjatinder S. Sekhon, Allison Lu, Juan Arredondo, David Sauer, Courtney Gravett, Gregory P. Mark, Sergei A. Grando, Eliot R. Spindel   +8 more
openalex   +1 more source

Nα-nitro L-arginine methylester and other alkyl esters of L-arginine are muscarinic antagonists

, 1992
Dennis J. Cheek, Delrae M. Eckman, Iain L. O. Buxton, Kathleen D. Keef   +3 more
openalex   +1 more source

Sleep-Predominant Lowering of Ambulatory Blood Pressure by Bedtime Inhalation of a Novel Muscarinic M3 Receptor Antagonist: A New “Bronchoantihypertensive” Strategy Targeting the Lung in Hypertension with Chronic Obstructive Pulmonary Disease [PDF]

, 2008
Kazuomi Kario, Hideyuki Uno, Kazuyuki Shimada   +2 more
openalex   +1 more source

Autonomic Nervous System in Bone Remodeling: From Mechanisms to Novel Therapies in Orthopedic Diseases

Orthopaedic Surgery, EarlyView.
Due to the close connection between the autonomic nervous system and skeletal system, large amounts of evidence have shown that neuromodulation plays a crucial role in regulating bone metabolism. Clinically, neuromodulation has exhibited promising therapeutic effects in treating joint disorders by significantly reducing inflammation and clinical scores.
Ruihao Xia, Hongjun Peng, Xishan Zhu, Wangdui Suolang, Steve T. L. Pambayi, Xiao Yang, Yi Zeng, Bin Shen   +7 more
wiley   +1 more source

Cholinergic neurons in the dorsomedial hypothalamus regulate food intake

Molecular Metabolism, 2017
Objective: Central cholinergic neural circuits play a role in the regulation of feeding behavior. The dorsomedial hypothalamus (DMH) is considered the appetite-stimulating center and contains cholinergic neurons.
Jae Hoon Jeong, Dong Kun Lee, Young-Hwan Jo   +2 more
doaj  

Synthesis and Biological Evaluation of Phenylacetyl Derivatives Having Low Central Nervous System Permeability as Potent and Selective M2 Muscarinic Receptor Antagonists.

, 1998
Toshihiro WATANABE, Akio KAKEFUDA, Akihiro Tanaka, Kenji TAKIZAWA, Seiko HIRANO, Hiroshi SHIBATA, Yoko Yamagiwa, Isao YANAGISAWA   +7 more
openalex   +2 more sources

A Novel Selective Muscarinic Acetylcholine Receptor Subtype 1 Antagonist Reduces Seizures without Impairing Hippocampus-Dependent Learning [PDF]

, 2009
Douglas J. Sheffler, Richard D. Williams, Thomas M. Bridges, Zixiu Xiang, Alexander S. Kane, Nellie Byun, Satyawan Jadhav, Mathew M. Mock, Fang Zheng, L. Michelle Lewis, Carrie K. Jones, Colleen M. Niswender, Charles D. Weaver, Craig W. Lindsley, P. Jeffrey Conn   +14 more
openalex   +1 more source

Treatable Trait Guided Asthma Management: A Feasibility Study

Respirology, EarlyView.
ABSTRACT Background and Objectives Treatable trait‐based personalised medicine improves outcomes in severe asthma clinics. We assessed the feasibility of a randomised controlled trial (RCT) of protocolised treatable trait‐guided asthma management in patients not under a severe asthma clinic. Methods Ten week single‐group cohort study.
James Fingleton, Rob McLachlan, Jenny Sparks, Richard Beasley, Alvar Agustí, Peter G. Gibson, Ian D. Pavord, Jo Hardy, Mark Weatherall, Allie Eathorne, Vanessa M. McDonald, the Treatable Traits Study Group, James Fingleton, Vanessa M. McDonald, Jo Hardy, Rob McLachlan, Peter G. Gibson, Ian D. Pavord, Alvar Agusti, Mark Weatherall, Richard Beasley, Augustus Anderson, Luisa Diputado, Allie Eathorne, James Fingleton, James Gilchrist, Jo Hardy, Mark Holliday, Kyley Kerse, John Martindale, Rob McLachlan, Nick Shortt, Jenny Sparks, Vanessa McDonald, Peter Gibson, Jasminka Nikolajevic‐Sarunac, Amber Smith, Paola Urroz   +37 more
wiley   +1 more source

inhibitor 2-[(4-methylphenyl)sulfonylcarbamido]-1-(4-nitrobenzyl)pyridinium bromide (2-AP27) is a muscarinic M2 receptor antagonist [PDF]

, 2009
Vytenis Arvydas Skeberdis, Vida Gendvilienė, Danguolė Zablockaitė, Irma Martišienė, Antanas Stankevičius   +4 more
openalex   +1 more source