Results 141 to 150 of about 52,496 (299)

Pharmacological and neurophysiological aspects of space/motion sickness [PDF]

A motorized motion testing device modeled after a Ferris wheel was constructed to perform motion sickness tests on cats. Details of the testing are presented, and some of the topics covered include the following: xylazine-induced emesis; analysis of the ...
Crampton, George H., Lucot, James B.
core   +1 more source

Krisanaklan Reduces Intestinal Anion and Fluid Secretion Through Inhibition of Na+/K+‐ATPase and K+ Channel Activity

Annals of the New York Academy of Sciences, EarlyView.
Krisanaklan reduces CFTR‐dependent intestinal chloride and fluid secretion by inhibiting the Na+,K+‐ATPase and K+ channels in epithelial cells. Consequently, this natural, plant‐derived product may limit secretory diarrhea caused by a diverse array of microbial pathogens. However, by dissipating the transmembrane Na+ gradient, Krisanaklan also inhibits
Tessa A. Groeneweg, Erdene Baigal, Anny Leung, Gert‐Jan Kremers, Marcel J. C. Bijvelds   +4 more
wiley   +1 more source

Characterization of Patients with Chronic Obstructive Pulmonary Disease Initiating Single-Inhaler Long-Acting Muscarinic Antagonist/Long-Acting β₂-Agonist Dual Therapy in a Primary Care Setting in England. [PDF]

Int J Chron Obstruct Pulmon Dis, 2022
Requena G, Banks V, Czira A, Wood R, Tritton T, Wild R, Compton C, Duarte M, Ismaila AS.   +8 more
europepmc   +1 more source

Micro‐Computed Tomography Based Whole Block Imaging of Asthma‐Associated Airway Remodeling With Mycobacterium avium‐Induced Cavity Formation: 3‐Dimensional Nondestructive Analysis

Pathology International, EarlyView.
Subpleural cavities are characteristic of Mycobacterium avium infections, but the precise route of infection remains unclear. Using merged micro‐computed tomography of multiple formalin‐fixed paraffin‐embedded (FFPE) blocks (merged whole block imaging), we visualized a continuous airway path from the hilum to a subpleural cavity.
Tetsuya Tsukamoto, Yasushi Hoshikawa, Alexei Teplov, Eiko Sakurai, Yasushi Matsuda, Hisato Ishizawa, Emmy Yanagita, Kaori Ushida, Naoya Asai, Kazuyoshi Imaizumi, Yukako Yagi   +10 more
wiley   +1 more source

Effect of Adding Inhaled Corticosteroid to Long-Acting Muscarinic Antagonist/Long-Acting Beta-Agonist Therapy Among Patients With Chronic Obstructive Pulmonary Disease. [PDF]

Cureus, 2021
Yuasa M, Tanaka Y, Tanaka T, Kashiwada T, Taniuchi N, Saito Y, Seike M, Hino M, Gemma A.   +8 more
europepmc   +1 more source

Agonist--Antagonist--Muscarinic Receptor Ternary Complex. [PDF]

Acta Chemica Scandinavica, 1980
Britta Hedlund, Anders Undén, Marlena Grynfarb, Tamas Bartfai, Curt R. Enzell   +4 more
openaire   +2 more sources

Test–retest reliability of Doppler ultrasound‐based leg blood flow assessments during exercise in patients with chronic obstructive pulmonary disease

Experimental Physiology, EarlyView.
Abstract Doppler ultrasound may be used to assess leg blood flow (Q̇leg${{\dot{Q}}_{{\mathrm{leg}}}}$), but the reliability of this method remains unexplored in patients with chronic obstructive pulmonary disease (COPD), where between‐subject variability may be larger than healthy due to peripheral vascular changes.
Milan Mohammad, Jacob P. Hartmann, Amalie B. Andersen, Helene L. Hartmeyer, Ulrik W. Iepsen, Ronan M. G. Berg   +5 more
wiley   +1 more source

Clinical potential of aclidinium bromide in chronic obstructive pulmonary disease

Therapeutics and Clinical Risk Management, 2014
Jun Zhong, Michael Roth Pneumology and Pulmonary Cell Research, Department of Biomedicine and Internal Medicine, University Hospital Basel, Basel, Switzerland Abstract: Chronic obstructive pulmonary disease (COPD) is increasing worldwide and is ...
Zhong J, Roth M
doaj  

Revefenacin, a once-daily, long-acting muscarinic antagonist, for nebulized maintenance therapy in patients with chronic obstructive pulmonary disease. [PDF]

Am J Health Syst Pharm, 2021
Hvisdas C.
europepmc   +1 more source

The role of agomelatine in appetite regulation and body weight in rats

Experimental Physiology, EarlyView.
Abstract The hypothalamic nuclei play a central role in the synthesis of anorexigenic and orexigenic neuropeptides, which are regulated by peripheral hormones, like leptin and ghrelin. Melatonergic receptors (MT1/MT2) are prominently expressed in the arcuate nucleus of the hypothalamus – an essential hub for appetite control – and in peripheral ...
Engin Korkmaz, Yavuz Erden, Çiğdem Tekin, Suat Tekin   +3 more
wiley   +1 more source