Results 141 to 150 of about 51,268 (235)

Nutritional Value and Memory‐Improving Effects of Seven Major Nuts: A Comprehensive Study Using Network Pharmacology and In Vivo Assays

Food Frontiers, Volume 7, Issue 2, March 2026.
This study highlights the memory‐enhancing effects of walnuts, almonds, and Torreya, with walnuts showing the strongest potential to improve cognitive function and delay brain aging. ABSTRACT This study explored the memory‐enhancing potential of seven commercially available nuts through nutritional profiling, metabolomics, network pharmacology, and ...
Jiamin Chen, Ben Niu, Ruiling Liu, Chaoyi Shen, Huizhi Chen, Mohamed A. Farag, Hangjun Chen, Qi Chen, Long Jin, Weijie Wu, Haiyan Gao   +10 more
wiley   +1 more source

Patient response and remission in respiratory disease: Special focus on severe asthma and chronic obstructive pulmonary disease

Journal of International Medical Research
Over the past decades, monoclonal antibodies have been playing a pivotal role in the treatment of chronic inflammatory airway diseases. Currently, ample data are available on the efficacy and safety of biologics in asthma from randomized controlled ...
Stefania Colantuono, Francesco Menzella, Pier-Valerio Mari, Francesco Macagno, Francesco Lombardi, Ilaria Baglivo, Cristiano Caruso   +6 more
doaj   +1 more source

A randomized controlled trial of long-acting muscarinic antagonist and long-acting β2 agonist fixed-dose combinations in patients with chronic obstructive pulmonary disease. [PDF]

BMC Pulm Med, 2021
Muraki M, Kunita Y, Shirahase K, Yamazaki R, Hanada S, Sawaguchi H, Tohda Y.   +6 more
europepmc   +1 more source

Evaluating and Determining the Effects of Psychotropic Drugs on Motor Vehicle Driving Performance: Key Considerations of the Japanese Guideline and Criteria for Clinical Implementation of Evidence

Neuropsychopharmacology Reports, Volume 46, Issue 1, March 2026.
The Japanese guideline and criteria for evaluating and determining the effects of psychotropic drugs on motor vehicle driving performance enable the clinical implementation of evidence by assessing “persistence of clinically meaningful impairment”. ABSTRACT The cross‐national differences in automobile driving precautions stated in psychotropic drug ...
Tetsuo Nakabayashi, Kunihiro Iwamoto, Akiko Yamaguchi, Yuki Konishi, Momoe Saji, Reiji Yoshimura, Kousuke Kanemoto, Hirofumi Aoki, Masahiko Ando, Norio Ozaki   +9 more
wiley   +1 more source

Cardiovascular effects of the intracerebroventricular injection of adrenomedullin: roles of the peripheral vasopressin and central cholinergic systems

Brazilian Journal of Medical and Biological Research, 2012
Our objective was to investigate in conscious Sprague-Dawley (6-8 weeks, 250-300 g) female rats (N = 7 in each group) the effects of intracerebroventricularly (icv) injected adrenomedullin (ADM) on blood pressure and heart rate (HR), and to determine if ...
B. Cam-Etoz, N. Isbil-Buyukcoskun, K. Ozluk   +2 more
doaj   +2 more sources

Comparison of the muscarinic antagonist effects of scopolamine and L-687,306. [PDF]

Behav Pharmacol, 2020
Winger G, Jutkiewicz EM, Woods JH.
europepmc   +1 more source

Schizophrenia is a TH2 dominant autoimmune disease possibly against acetylcholine receptors of CNS [PDF]

, 2012
Schizophrenia is a very common psychiatric disorder. However, its etiology and pathogenesis is still unknown. Current theory saying that neurotransmitter imbalance such as serotonin or dopamine only provides limited effectiveness in schizophrenia ...
Wanchung(Wan-Jiung) Hu
core   +1 more source

Lactoferrin treatment activates acetylcholinesterase, decreasing acetylcholine levels in non‐small cell lung cancer (NSCLC) cell culture supernatants, inhibiting cell survival

FEBS Open Bio, Volume 16, Issue 2, Page 412-431, February 2026.
Representation of the suggested mode of action of lactoferrin (Lf) in nonsmall cell lung cancer (NSCLC) A549 cells. Lf induces activation of caspase‐3 by activating p53 and AChE leading to decreased ACh concentrations. In turn, ACh signaling leads to activation of VEGF and AKT and blocking of caspase‐3.
Stuti Goel, Caroline Wozniak, Aya Sabri, Ben Haddad, Brooke Lopo, Alvaro Cobos, Sarah Sarofim, Jeffrey Guthrie, Deborah Heyl, Hedeel Guy Evans   +9 more
wiley   +1 more source

Subicular Astrocytes Govern Seizure‐Impaired Fear Memory

Advanced Science, Volume 13, Issue 7, 3 February 2026.
Astrocytes in dorsal subiculum act as a critical modulator of seizure‐associated cognitive dysfunction, operating through a Ca2+‐dependent adenosine‐linked astrocyte‐neuron signaling pathway that disrupts neuronal circuit homeostasis. This research highlights the potential of astrocyte‐targeted interventions as a therapeutic strategy, moving beyond the
Yuying Shao, Jing Xi, Yuhao Sun, Yulan Li, Zhisheng Li, Wangjialu Lu, Jialu Chen, Lin Yang, Fan Fei, Heming Cheng, Li Cheng, Cenglin Xu, Zhuo Huang, Vladimir Parpura, Yi Wang, Zhong Chen   +15 more
wiley   +1 more source

A Systematic Review on Functional Bioactive Compound Atractylone: Natural Source, Pharmacological Properties and Mechanisms Insights

Food Science &Nutrition, Volume 14, Issue 2, February 2026.
Atractylone exhibits diverse pharmacological effects, including anticancer and neuroprotection. A systematic review was conducted following PRISMA guidelines to analyze Atractylone. This study explores Atractylone's sources, biosynthesis, and therapeutic potential.
Hamza Elhrech, Oumayma Aguerd, Meriem El Fessikh, Zouhair Essahli, Taoufiq Benali, Waleed Al Abdulmonem, Learn‐Han Lee, Imane Chamkhi, Abdelhakim Bouyahya   +8 more
wiley   +1 more source