Results 151 to 160 of about 2,979 (198)

Intraocular Pressure Increase Induced by 0.5% Tropicamide‐0.5% Phenylephrine in Dogs: An Analysis of Causes Using Ultrasound Biomicroscopy

Veterinary Ophthalmology, EarlyView.
ABSTRACT Purpose To determine whether the differences in intraocular pressure (IOP) change after the topical application of 0.5% tropicamide and 0.5% phenylephrine (TP) are due to anatomical variations in the anterior chamber using ultrasound biomicroscopy (UBM).
Donghee Kim, Sang‐Eun Park, Haerin Yoon, Jiyi Hwang, Ji Seung Jung, Soohyun Kim, Kyung‐Mee Park   +6 more
wiley   +1 more source

Activity of aclidinium bromide, a new long‐acting muscarinic antagonist: a phase I study [PDF]

, 2010
Vanessa Schelfhout, P. Ferrer, Josep M. Jansat, Francesc Peris, Esther Garcia Gil, Romain Pauwels, Guy Joos   +6 more
openalex   +1 more source

Test–retest reliability of Doppler ultrasound‐based leg blood flow assessments during exercise in patients with chronic obstructive pulmonary disease

Experimental Physiology, EarlyView.
Abstract Doppler ultrasound may be used to assess leg blood flow (Q̇leg${{\dot{Q}}_{{\mathrm{leg}}}}$), but the reliability of this method remains unexplored in patients with chronic obstructive pulmonary disease (COPD), where between‐subject variability may be larger than healthy due to peripheral vascular changes.
Milan Mohammad, Jacob P. Hartmann, Amalie B. Andersen, Helene L. Hartmeyer, Ulrik W. Iepsen, Ronan M. G. Berg   +5 more
wiley   +1 more source

Dose-Related Efficacy of GSK573719: A Long-Acting Muscarinic Receptor Antagonist (LAMA) With Sustained 24-Hour Activity in COPD [PDF]

, 2011
James F. Donohue, Antonio Anzueto, Jean Brooks, Rashmi Mehta, Chris Kalberg, Glenn Crater   +5 more
openalex   +1 more source

Methacholine hyperresponsiveness in mice with house dust mite‐induced lung inflammation is not associated with excessive airway constriction ex vivo

Experimental Physiology, EarlyView.
Abstract The role of excessive airway constriction in the hyperresponsiveness to nebulized methacholine in mice with experimental asthma is still contentious. Yet, there have been very few studies investigating whether the increased in vivo response to methacholine caused by experimental asthma is associated with a corresponding increase in ex vivo ...
Andrés Rojas‐Ruiz, Magali Boucher, Cyndi Henry, Louis Gélinas, Rosalie Packwood, Percival Graham, Jorge Soliz, Ynuk Bossé   +7 more
wiley   +1 more source

Synthesis of New Cardioselective M2 Muscarinic Receptor Antagonists.

, 2000
Giacomina R. Mandelli, Stefano Maiorana, Patrizia Terni, Giuseppina Lamperti, Maria Luisa Colibretti, Bruno P. Imbimbo   +5 more
openalex   +2 more sources

Subcutaneous Administration of Muscarinic Antagonists and Triple-Immunostaining of the Levator Auris Longus Muscle in Mice [PDF]

, 2011
Megan C. Wright, Amy Kim, Young‐Jin Son   +2 more
openalex   +1 more source

Translating physiology of the arterial chemoreflex into novel therapeutic interventions targeting carotid bodies in cardiometabolic disorders

The Journal of Physiology, EarlyView.
Abstract figure legend The carotid body develops aberrant high activity in chronic heart failure, resistant hypertension, obstructive sleep apnoea (OSA) and diabetes. Hyperactivity of the carotid body leads to both high tonicity and increased sensitivity of the arterial chemoreflex with resultant sympathoexcitation.
Tymoteusz Żera, Bartłomiej Paleczny, Maciej Siński, Sílvia V. Conde, Krzysztof Narkiewicz, Piotr Ponikowski, Julian F.R. Paton, Piotr Niewiński   +7 more
wiley   +1 more source

Structure of the human M2 muscarinic acetylcholine receptor bound to an antagonist [PDF]

, 2012
Kazuko Haga, Andrew C. Kruse, Hidetsugu Asada, Takami Yurugi-Kobayashi, Mitsunori Shiroishi, Cheng Zhang, William I. Weis, Tetsuji Okada, Brian K. Kobilka, Tatsuya Haga, Takuya Kobayashi   +10 more
openalex   +1 more source

Endothelial TRPV4–Cx43 signalling complex regulates vasomotor tone in resistance arteries

The Journal of Physiology, EarlyView.
Abstract figure legend In this study, we investigate, for the first time, the role of endothelial Cx43 hemichannels (hCx43) in the regulation of vasomotor tone. We discovered that TRPV4 channels and Cx43 are in proximity within the endothelium of mouse arterioles.
Pía C. Burboa, Pablo S. Gaete, Ping Shu, Priscila A. Araujo, Annie V. Beuve, Walter N. Durán, Jorge E. Contreras, Mauricio A. Lillo   +7 more
wiley   +1 more source