Results 161 to 170 of about 2,979 (198)

Chemogenetic Control of Striatal Astrocytes Improves Parkinsonian Motor Deficits in Mice

Glia, Volume 73, Issue 6, Page 1188-1202, June 2025.
Main Points Dopamine depletion reduces locomotion‐induced calcium activity in dorsal striatal astrocytes. Chemogenetic activation facilitates astrocyte locomotion responses and improves motor behavior in dopamine lesioned animals. ABSTRACT Parkinson's disease (PD) is characterized by the degeneration of dopaminergic nigrostriatal inputs, which causes ...
Wesley R. Evans, Sindhuja S. Baskar, Angelica Vellore, Ana Raquel Castro E. Costa, Cynthia Jacob, Sanya Ravoori, Abimbola Arigbe, Rafiq Huda   +7 more
wiley   +1 more source

Beneficial Effect of Muscarinic-2 Antagonist on Dilated Cardiomyopathy Induced by Autoimmune Mechanism against Muscarinic-2 Receptor

, 2001
Shinobu Matsui, Michael Fu, Mitsuru Hayase, Shogo Katsuda, Nobuo Yamaguchi, Kohei Teraoka, Takayuki Kurihara, Noboru Takekoshi   +7 more
openalex   +1 more source

Inhaled beta-2-agonists/muscarinic antagonists and acute myocardial infarction in COPD patients [PDF]

, 2014
Marietta Rottenkolber, Dominik Rottenkolber, Rainald Fischer, Luisa Ibáñez, Joan Fortuny, Elena Ballarín, Mònica Sabaté, Pili Ferrer, Petra Thürmann, Joerg Hasford, Sven Schmiedl   +10 more
openalex   +1 more source

What is the influence of exacerbations on pulmonary function in pediatric and adolescent patients with severe asthma despite controller therapies?

Clinical and Translational Allergy, Volume 15, Issue 4, April 2025.
Abstract Background Although exacerbations are common in severe asthma, there have been few longitudinal studies evaluating their effect on lung function parameters. This study aimed to evaluate the impact of exacerbations on lung function in children and adolescents with severe asthma in Brazil.
A. Z. P. Brandão, L. M. L. B. F. Lasmar, L. M. A. S. Pertence, M. I. R. Vieira, G. B. Lasmar, V. O. Ganem, E. V. Mancuzo, M. V. N. P. de Queiroz   +7 more
wiley   +1 more source

Synthesis of a Muscarinic Receptor Antagonist via a Diastereoselective Michael Reaction, Selective Deoxyfluorination and Aromatic Metal-Halogen Exchange Reaction.

, 2001
Toshiaki Mase, Ioannis N. Houpis, Atsushi Akao, Ilias Dorziotis, Khateeta M. Emerson, Thoa Hoang, Takehiko Iida, Takahiro Itoh, Keisuke Kamei, Shinji Kato, M. Kawasaki, Fengrui Lang, Jaemoon Lee, Joseph P. Lynch, Peter E. Maligres, Audrey Molina, Takayuki Nemoto, Shigemitsu Okada, Robert A. Reamer, Zhiguo J. Song, David M. Tschaen, Toshihiro Wada, David Zewge, R. P. Volante, Paul J. Reider, Koji Tomimoto   +25 more
openalex   +1 more source

The Muscarinic Antagonist MT3 Distinguishes Between Form Deprivation- and Negative Lens-Induced Myopia in Chicks [PDF]

, 2014
Debora L. Nickla, Yekaterina Yusupova, Kristen Totonelly   +2 more
openalex   +1 more source

Current evidence for COPD management with dual long-acting muscarinic antagonist/long-acting β₂-agonist bronchodilators [PDF]

, 2020
NEIL SKOLNIK, Trang Susan Nguyen, Aarisha Shrestha, Riju Ray, Thomas Corbridge, Stephen Brunton   +5 more
openalex   +1 more source

Key lines of discovery in myopia research

Ophthalmic and Physiological Optics, EarlyView.
Frank Schaeffel, Jeremy A. Guggenheim, Richard A. Stone, Christine F. Wildsoet   +3 more
wiley   +1 more source

Phenotyping patients with chronic obstructive pulmonary disease and heart failure

ESC Heart Failure, Volume 12, Issue 2, Page 900-911, April 2025.
Central illustration. Abbreviations: ACEi, angiotensin‐converting enzyme inhibitor; ARB, angiotensin receptor blocker; ARNi, angiotensin‐receptor‐neprilysin inhibitor; CI, confidence interval; COPD, chronic obstructive pulmonary disease; CRT, cardiac resynchronization therapy; CV, cardiovascular; EF, ejection fraction; eGFR, estimated glomerular ...
Peter Moritz Becher, Felix Lindberg, Lina Benson, Camilla Hage, Ulf Dahlström, Stephan Rosenkranz, Francesco Cosentino, Giuseppe M.C. Rosano, Stefan Blankenberg, Paulus Kirchhof, Frieder Braunschweig, Lars H. Lund, Gianluigi Savarese   +12 more
wiley   +1 more source

Apparent capacity of cardiac muscarinic receptors for different radiolabeled antagonists☆

, 2001
Chi Shing Sum, Norman Pyo, James W. Wells   +2 more
openalex   +1 more source