Discovery, Synthesis and Characterization of a Highly Muscarinic Acetylcholine Receptor (mAChR)‐Selective M5‐Orthosteric Antagonist, VU0488130 (ML381): A Novel Molecular Probe [PDF]
Patrick R. Gentry+15 more
openalex +1 more source
Abstract Introduction (1) Assess the harmonization of structured electronic health record data (laboratory results and medications) to reference terminologies and characterize the severity of issues. (2) Identify issues of data completeness by comparing complementary data domains, stratifying by time, care setting, and provenance.
Keith Marsolo+14 more
wiley +1 more source
The M1 Muscarinic Receptor Antagonist VU0255035 Delays the Development of Status Epilepticus after Organophosphate Exposure and Prevents Hyperexcitability in the Basolateral Amygdala [PDF]
Steven L. Miller+6 more
openalex +1 more source
Bis-Quinolinium Cyclophane Blockers of SK Potassium Channels Are Antagonists of M3 Muscarinic Acetylcholine Receptors [PDF]
Vladislav Bugay+9 more
openalex +1 more source
European Guideline on Chronic Nausea and Vomiting—A UEG and ESNM Consensus for Clinical Management
ABSTRACT Introduction Chronic nausea and vomiting are symptoms of a wide range of gastrointestinal and non‐gastrointestinal conditions. Diagnosis can be challenging and requires a systematic and well‐structured approach. If the initial investigation for structural, toxic and metabolic disorders is negative, digestive motility and gut‐brain interaction ...
Carolina Malagelada+34 more
wiley +1 more source
Combination therapy with β3‐adrenoceptor agonists and muscarinic acetylcholine receptor antagonists: Efficacy in rats with bladder overactivity [PDF]
Akira Furuta+5 more
openalex +1 more source
A Survey of Physicians' Perceptions About Using Long-Acting Muscarinic Antagonist for Hospitalized COPD Patients [PDF]
Shaha Nabeel+7 more
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Positioning of Long-Acting Muscarinic Antagonists in the Management of Asthma [PDF]
René Aalbers, Hae‐Sim Park
openalex +1 more source
Point‐of‐Care Blood Eosinophils to Predict Preschool Wheeze Attacks
Absolute and % BEC at baseline are higher in children who had > 1 wheeze attack requiring unscheduled healthcare attendance in follow‐up period. Decision tree model shows children with BEC ≥ 4% and TRACK score < 75 are more likely to have a future attack.
Kushalinii Hillson+17 more
wiley +1 more source